APPLIED THERAPEUTICS INC (APLT) Stock Institutional Trading Activity


APPLIED THERAPEUTICS INC (APLT) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

Explore more:

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCBuy2,530,3562,706,156$270,616
Q1 2024Renaissance Technologies LLCSell-477,287175,800$1,195
Q4 2023Renaissance Technologies LLCBuy237,609653,087$2,188
Q3 2023Renaissance Technologies LLCBuy8,100415,478$1,035
Q2 2023Renaissance Technologies LLCBuy187,578407,378$521
Q1 2023Renaissance Technologies LLCSell-98,178219,800$178
Q4 2022Renaissance Technologies LLCSell-16,311317,978$242
Q3 2022Renaissance Technologies LLCBuy70,111334,289$311
Q2 2022Renaissance Technologies LLCSell-18,022264,178$250
Q1 2022Renaissance Technologies LLCBuy264,600282,200$595
Q4 2021Renaissance Technologies LLCSell-1,88617,600$158
Q1 2020Renaissance Technologies LLCBuy19,48619,486$637

Frequently asked questions about APLT activity

  • Which institutional owners are buying APLT?

    Institutional owners buying APLT include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in APLT activity?

    "Buy" means an investor increased their reported position in APLT compared to the prior reporting period. This reflects growing exposure to APPLIED THERAPEUTICS INC (APLT) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in APLT increasing?

    Institutional interest in APLT can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.