MILESTONE SCIENTIFIC INC (MLSS) Stock Institutional Trading Activity


MILESTONE SCIENTIFIC INC (MLSS) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC and Sequoia Financial Advisors. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCBuy2,60082,897$22,631
Q3 2025Renaissance Technologies LLCBuy7,10080,297$36,479
Q2 2025Sequoia Financial AdvisorsSell-1,57843,422$27,639
Q2 2025Renaissance Technologies LLCSell-4,55973,197$46,590
Q1 2025Renaissance Technologies LLCSell-48,51977,756$72,515
Q4 2024Renaissance Technologies LLCBuy53,198126,275$121,224
Q3 2024Renaissance Technologies LLCBuy29,18073,077$66,537
Q2 2024Renaissance Technologies LLCSell-46,60043,897$29,995
Q1 2024Renaissance Technologies LLCSell-23,90090,497$56
Q1 2024Sequoia Financial AdvisorsSell-11,51645,000$28,035
Q4 2023Renaissance Technologies LLCBuy86,500114,397$79
Q3 2023Renaissance Technologies LLCBuy6,70027,897$26
Q2 2023Renaissance Technologies LLCSell-1,88121,197$18
Q1 2022Renaissance Technologies LLCSell-132,62423,078$35
Q1 2022Sequoia Financial AdvisorsBuy56,51656,516$86
Q4 2021Renaissance Technologies LLCSell-470,392155,702$321
Q3 2021Renaissance Technologies LLCSell-315,434626,094$1,171
Q2 2021Renaissance Technologies LLCBuy871,628941,528$2,307
Q1 2021Renaissance Technologies LLCSell-147,50069,900$250
Q1 2020Renaissance Technologies LLCBuy125,129217,400$272
Q4 2019Renaissance Technologies LLCBuy73,77192,271$128
Q3 2016Renaissance Technologies LLCBuy18,50018,500$40

Frequently asked questions about MLSS activity

  • Which institutional owners are buying MLSS?

    Institutional owners buying MLSS include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in MLSS activity?

    "Buy" means an investor increased their reported position in MLSS compared to the prior reporting period. This reflects growing exposure to MILESTONE SCIENTIFIC INC (MLSS) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in MLSS increasing?

    Institutional interest in MLSS can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.