Howard Hughes Medical Institute Increases Holdings in KLA Corp and Booking Holdings
The Howard Hughes Medical Institute (HHMI) disclosed significant purchases of KLA Corporation (KLAC) and Booking Holdings Inc. (BKNG) during Q2 2026, marking substantial new positions.

According to the latest filing from Howard Hughes Medical Institute, there were notable changes in its portfolio during Q2 2026. The investor, known for its selective approach and focus on long-term value, appears to have focused purely on acquiring new positions.
The most significant change was the establishment of a new position in KLA Corporation (KLAC), which is categorized under Technology. The filing shows that HHMI acquired 18,250 shares during this quarter alone, representing an unprecedented increase of 900% from the previous period's holdings.
Similarly, in the Consumer Cyclical sector, HHMI disclosed a major purchase of Booking Holdings Inc. (BKNG). The investor bought 11,100 shares this quarter, resulting in a staggering increase of over 2400% compared to the prior period.
These two new positions accounted for approximately half of HHMI's disclosed activity during Q2. Both holdings are relatively small but significant additions to their portfolio, increasing KLAC's allocation from zero (or negligible) to about 1.24%, and BKNG's from near-zero to around 0.44%.
KLAC is a leading Technology company specializing in providing systems for the semiconductor industry. Booking Holdings operates major online travel platforms, representing exposure within the thriving Consumer Cyclical sector. These additions suggest confidence in these specific companies' prospects or strategic fit with HHMI's investment criteria.
In contrast to these new purchases, there were no disclosed sales during this quarter according to HHMI's filing. All other holdings listed appear unchanged from the previous period, indicating that existing positions were maintained and not divested by the investor in Q2 2026.