CUE BIOPHARMA INC (CUE) Stock Institutional Trading Activity


CUE BIOPHARMA INC (CUE) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC and First Eagle U.S. Value. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCBuy11,290238,354$72,793
Q3 2025Renaissance Technologies LLCBuy93,600227,064$163,191
Q2 2025Renaissance Technologies LLCBuy96,518133,464$91,063
Q1 2025Renaissance Technologies LLCSell-237,08736,946$33,658
Q1 2024Renaissance Technologies LLCBuy186,833274,033$518
Q4 2023Renaissance Technologies LLCBuy27,40087,200$230
Q3 2023Renaissance Technologies LLCSell-95,20059,800$138
Q2 2023Renaissance Technologies LLCBuy103,900155,000$566
Q1 2023Renaissance Technologies LLCSell-90,60051,100$182
Q4 2022Renaissance Technologies LLCSell-284,447141,700$404
Q3 2022Renaissance Technologies LLCSell-153,553426,147$950
Q2 2022Renaissance Technologies LLCBuy60,400579,700$1,443
Q1 2022Renaissance Technologies LLCBuy414,700519,300$2,534
Q4 2021Renaissance Technologies LLCBuy36,300104,600$1,183
Q4 2020Renaissance Technologies LLCSell-55,19668,300$854
Q3 2020Renaissance Technologies LLCBuy22,496123,496$1,859
Q2 2020Renaissance Technologies LLCBuy20,607101,000$2,476
Q1 2020Renaissance Technologies LLCBuy37,00080,393$1,141
Q4 2019Renaissance Technologies LLCBuy43,39343,393$689
Q2 2018First Eagle U.S. ValueSell-305,000195,000$2,313
Q1 2018First Eagle U.S. ValueBuy500,000500,000$7,025

Frequently asked questions about CUE activity

  • Which institutional owners are buying CUE?

    Institutional owners buying CUE include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in CUE activity?

    "Buy" means an investor increased their reported position in CUE compared to the prior reporting period. This reflects growing exposure to CUE BIOPHARMA INC (CUE) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in CUE increasing?

    Institutional interest in CUE can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.