ISHARES BIOTECHNOLOGY ETF (IBB) Institutional Ownership Changes & 13F Activity

ISHARES BIOTECHNOLOGY ETF (IBB) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q1 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC, Sequoia Financial Advisors, Matrix Private Capital Group, Appaloosa Management, and Eagle Capital Management.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q1 2026Renaissance Technologies LLCSell-20,2006,200$1,046,870
Q1 2026Sequoia Financial AdvisorsSell-3673,092$522,082
Q4 2025Renaissance Technologies LLCSell-1,08226,400$4,455,528
Q4 2025Sequoia Financial AdvisorsBuy1193,459$583,828
Q3 2025Renaissance Technologies LLCBuy14,38227,482$3,967,576
Q2 2025Sequoia Financial AdvisorsSell-3443,340$422,518
Q1 2025Sequoia Financial AdvisorsBuy4793,684$471,155
Q4 2024Renaissance Technologies LLCBuy60013,100$1,731,951
Q4 2024Sequoia Financial AdvisorsBuy5973,205$423,795
Q3 2024Sequoia Financial AdvisorsBuy1992,608$379,716
Q1 2024Sequoia Financial AdvisorsBuy3492,409$330,596
Q4 2023Sequoia Financial AdvisorsSell-8772,060$279,886
Q3 2023Sequoia Financial AdvisorsSell-1132,937$359,146
Q2 2023Sequoia Financial AdvisorsSell-8703,050$387,233
Q1 2023Renaissance Technologies LLCBuy1,90012,500$1,615
Q1 2023Sequoia Financial AdvisorsBuy9663,920$506,349
Q1 2023Matrix Private Capital GroupBuy400400$51,664
Q4 2022Sequoia Financial AdvisorsSell-922,954$387,844
Q3 2022Renaissance Technologies LLCSell-24,40010,600$1,240
Q3 2022Sequoia Financial AdvisorsSell-2,5603,046$356
Q2 2022Renaissance Technologies LLCBuy33,40035,000$4,117
Q2 2022Sequoia Financial AdvisorsSell-325,606$659
Q1 2022Renaissance Technologies LLCSell-9,1951,600$208
Q1 2022Sequoia Financial AdvisorsSell-5,9585,638$735
Q4 2021Sequoia Financial AdvisorsBuy10,31311,596$1,770
Q3 2021Sequoia Financial AdvisorsSell-9,1381,283$207
Q2 2021Sequoia Financial AdvisorsBuy95410,421$1,705
Q1 2021Sequoia Financial AdvisorsBuy1,7839,467$1,425
Q4 2020Renaissance Technologies LLCBuy6,09510,795$1,635
Q4 2020Sequoia Financial AdvisorsBuy2,9787,684$1,164

Frequently asked questions about IBB activity

  • Which institutional owners are buying IBB?

    Institutional owners buying IBB include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in IBB activity?

    "Buy" means an investor increased their reported position in IBB compared to the prior reporting period. This reflects growing exposure to ISHARES BIOTECHNOLOGY ETF (IBB) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in IBB increasing?

    Institutional interest in IBB can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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