IONIS PHARMACEUTICALS INC (IONS) Institutional Ownership
IONS is currently held by 3 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $215.50M based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026.
The largest disclosed holder is Tweedy, Browne Co All Funds (US), which reported ownership valued at approximately $170.88M in its March 31, 2026 13F filing. Based on current market prices and the latest disclosed share count, Tweedy, Browne Co All Funds (US)'s IONS position is now estimated to be worth approximately $169.10M, representing an estimated loss of -1.04% since the filing period.
Major shareholders tracked on this page include Tweedy, Browne Co All Funds (US), Renaissance Technologies LLC, ARK Invest, and other prominent asset managers. Collectively, these investors account for approximately 100% of the total disclosed value among the investors covered in this analysis.
This page tracks institutional holding trends, hedge fund exposure, portfolio concentration, historical 13F filings, and estimated holding performance to help investors analyze smart money sentiment toward IONIS PHARMACEUTICALS INC (IONS).
Institutional Ownership Trend
| Portfolio quarter | Institutional holders | Total reported value | Total shares |
|---|---|---|---|
| Q1 2026 | 3 | $215,500,075 | 2,869,890 |
| Q4 2025 | 3 | $246,151,184 | 3,111,505 |
| Q3 2025 | 3 | $262,932,462 | 4,019,145 |
| Q2 2025 | 3 | $160,528,349 | 4,062,980 |
| Q1 2025 | 3 | $124,830,141 | 4,137,559 |
| Q4 2024 | 3 | $156,608,105 | 4,479,637 |
| Q3 2024 | 3 | $201,480,130 | 5,029,459 |
| Q2 2024 | 3 | $241,408,160 | 5,065,215 |
| Q1 2024 | 3 | $210,451,583 | 5,034,242 |
| Q4 2023 | 3 | $271,154,551 | 5,472,146 |
| Q3 2023 | 3 | $266,572,086 | 6,146,340 |
| Q2 2023 | 3 | $99,561,045 | 6,333,989 |
Related IONS Institutional Insights:
- IONS Institutional Ownership & Insiders Activity
- IONS Institutional Ownership & 13F Activity
- IONS Top Institutional Shareholders
- IONS Institutional Buying Activity
- IONS Institutional Selling Activity
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- IONS Insider Trading & SEC Form 4 Activity
- Top Institutional Investor Stock Rankings