IONIS PHARMACEUTICALS INC (IONS) Institutional Ownership Changes & 13F Activity

IONIS PHARMACEUTICALS INC (IONS). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Royal Bank Of Canada, T. Rowe Price Investment Management, Inc., Barclays Plc, Wellington Management Group Llp, and Invesco Ltd..

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Manufacturers Life Insurance Company, TheSell-28,860-19.3%120,678$9.57MQ2 2026Sep 09, 2026
Integrated Wealth Concepts LlcBuy+202+7.4%2,926$232.00KQ2 2026Sep 09, 2026
Parkside Financial Bank & TrustSell-4-1.6%254$20.14KQ2 2026Sep 04, 2026
Citadel Advisors LlcSell-706,250-74.9%236,284$18.73MQ2 2026Sep 02, 2026
Allianz Asset Management GmbhBuy+3,528+28.0%16,129$1.28MQ2 2026Sep 02, 2026
Corient Private Wealth LlcBuy+62+0.0%196,661$15.59MQ2 2026Aug 27, 2026
California State Teachers Retirement SystemBuy+4,464+2.5%180,949$14.35MQ2 2026Aug 24, 2026
Assenagon Asset Management S.A.Buy+7,254+21.5%40,927$3.25MQ2 2026Aug 21, 2026
Mercer Global Advisors IncBuy+622+9.9%6,918$548.41KQ2 2026Aug 19, 2026
North Star Asset Management IncSell-50-0.3%16,560$1.31MQ2 2026Aug 18, 2026
Empowered Funds, LlcBuy+120,001+116.3%223,142$17.69MQ2 2026Aug 17, 2026
Jefferies Financial Group Inc.Sell-20,400-34.5%38,665$3.07MQ2 2026Aug 17, 2026
Public Employees Retirement System Of OhioBuy+832+1.8%46,862$3.72MQ2 2026Aug 17, 2026
Transamerica Financial Advisors, LlcSell-12-36.4%21$1.67KQ2 2026Aug 17, 2026
Royal Bank Of CanadaBuy+2,380,664+62.6%6,182,479$490.21MQ2 2026Aug 14, 2026
T. Rowe Price Investment Management, Inc.Sell-2,199,655-35.7%3,959,372$313.94MQ2 2026Aug 14, 2026
Barclays PlcBuy+1,313,262+453.0%1,603,136$127.11MQ2 2026Aug 14, 2026
Wellington Management Group LlpBuy+1,259,599+19.7%7,651,415$606.68MQ2 2026Aug 14, 2026
Invesco Ltd.Buy+1,120,7071,120,707$88.86MQ2 2026Aug 14, 2026
Alyeska Investment Group, L.P.Buy+944,766+199.7%1,417,916$112.43MQ2 2026Aug 14, 2026
Groupama Asset ManagmentBuy+937,083937,083$75.20MQ2 2026Aug 14, 2026
Bellevue Group AgSell-846,407-46.5%972,258$77.09MQ2 2026Aug 14, 2026
Millennium Management LlcSell-762,634-72.5%288,872$22.90MQ2 2026Aug 14, 2026
Polar Capital Holdings PlcBuy+624,510+75.3%1,454,021$115.29MQ2 2026Aug 14, 2026
Summit Partners Public Asset Management, LlcSell-616,770-43.9%787,263$62.42MQ2 2026Aug 14, 2026
Squarepoint Ops LlcSell-585,897-84.3%109,379$8.67MQ2 2026Aug 14, 2026
Nomura Asset Management International Inc.Buy+515,111+65.6%1,300,392$103.11MQ2 2026Aug 14, 2026
Goldman Sachs Group IncBuy+410,098+24.1%2,109,945$167.30MQ2 2026Aug 14, 2026
Two Sigma Investments, LpBuy+394,713+6.7%6,252,342$495.75MQ2 2026Aug 14, 2026
Freestone Grove Partners LpBuy+339,967339,967$26.96MQ2 2026Aug 14, 2026
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Frequently asked questions about IONS activity

  • Which institutional owners are buying IONS?

    Institutional owners buying IONS include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in IONS activity?

    "Buy" means an investor increased their reported position in IONS compared to the prior reporting period. This reflects growing exposure to IONIS PHARMACEUTICALS INC (IONS) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in IONS increasing?

    Institutional interest in IONS can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.