LEXICON PHARMACEUTICALS INC (LXRX) Institutional Ownership
LXRX is currently held by 1 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $2.50M based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026.
The largest disclosed holder is Renaissance Technologies LLC, which reported ownership valued at approximately $2.50M in its March 31, 2026 13F filing. Based on current market prices and the latest disclosed share count, Renaissance Technologies LLC's LXRX position is now estimated to be worth approximately $3.27M, representing an estimated gain of +30.77% since the filing period.
Major shareholders tracked on this page include Renaissance Technologies LLC, and other prominent asset managers. Collectively, these investors account for approximately 100% of the total disclosed value among the investors covered in this analysis.
This page tracks 13F-reported ownership trends, hedge fund exposure, portfolio concentration, historical 13F filings, and estimated holding performance to help investors analyze smart money sentiment toward LEXICON PHARMACEUTICALS INC (LXRX).
Institutional Ownership Trend
| Portfolio quarter | Institutional holders | Total reported value | Total shares |
|---|---|---|---|
| Q1 2026 | 1 | $2,496,780 | 1,600,500 |
| Q4 2025 | 1 | $302,742 | 263,254 |
| Q3 2025 | 1 | $394,740 | 292,400 |
| Q4 2024 | 1 | $37,768 | 51,141 |
| Q4 2023 | 1 | $631 | 412,175 |
| Q3 2023 | 1 | $297 | 272,255 |
| Q1 2023 | 1 | $641 | 263,875 |
| Q4 2022 | 1 | $751 | 393,285 |
| Q3 2022 | 1 | $1,155 | 481,375 |
| Q1 2022 | 1 | $186 | 88,776 |
| Q2 2021 | 1 | $274 | 59,775 |
| Q1 2021 | 1 | $1,834 | 312,479 |
Related LXRX Institutional Insights:
- LXRX Institutional Ownership & Insiders Activity
- LXRX Institutional Ownership & 13F Activity
- LXRX Top Institutional Shareholders
- LXRX Institutional Buying Activity
- LXRX Institutional Selling Activity
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- LXRX Insider Trading & SEC Form 4 Activity
- Top Institutional Investor Stock Rankings