MDGL Institutional Ownership Changes & 13F Activity


MADRIGAL PHARMACEUTICALS INC (MDGL) institutional ownership data tracks hedge funds, asset managers, pension funds, and institutional investors holding Amazon shares based on recent SEC 13F filings (Q4 2025). Recent filings show notable position changes from firms including Renaissance Technologies LLC. This page analyzes institutional buying and selling activity, increased and reduced positions, new holdings, and sold-out positions to help investors understand institutional sentiment, portfolio allocation trends, and hedge fund conviction in MADRIGAL PHARMACEUTICALS INC stock.


Key Insights:

  • Q4 2025 SEC 13F filings show notable institutional position changes in MDGL.
  • Renaissance Technologies LLC were among firms reporting significant share count changes.
  • Institutional ownership trends can help investors monitor hedge fund sentiment and long-term conviction in MDGL stock.

Related MDGL Insights:

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCSell-36,82083,862$48,836,197
Q3 2025Renaissance Technologies LLCBuy109,846120,682$55,352,006
Q2 2025Renaissance Technologies LLCSell-74,25010,836$3,279,407
Q1 2025Renaissance Technologies LLCSell-75,69685,086$28,183,036
Q4 2024Renaissance Technologies LLCBuy116,285160,782$49,612,502
Q3 2024Renaissance Technologies LLCSell-23,58544,497$9,443,153
Q3 2023Renaissance Technologies LLCSell-10,60068,082$9,943
Q2 2023Renaissance Technologies LLCSell-96,70078,682$18,176
Q1 2023Renaissance Technologies LLCBuy170,800175,382$42,488
Q4 2022Renaissance Technologies LLCSell-2184,582$1,330
Q1 2022Renaissance Technologies LLCBuy2,4004,800$471
Q4 2021Renaissance Technologies LLCSell-14,7112,400$203
Q3 2021Renaissance Technologies LLCSell-35,87117,111$1,365
Q2 2021Renaissance Technologies LLCBuy18,70052,982$5,161
Q1 2021Renaissance Technologies LLCBuy24934,282$4,010
Q4 2020Renaissance Technologies LLCBuy12,25134,033$3,783
Q3 2020Renaissance Technologies LLCSell-50,60021,782$2,586
Q2 2020Renaissance Technologies LLCBuy45,90072,382$8,197
Q1 2020Renaissance Technologies LLCSell-61,10526,482$1,768
Q4 2017Renaissance Technologies LLCSell-39,70087,587$8,040
Q3 2017Renaissance Technologies LLCBuy51,900127,287$5,725
Q2 2017Renaissance Technologies LLCBuy17,51275,387$1,226
Q1 2017Renaissance Technologies LLCBuy40057,875$891
Q4 2016Renaissance Technologies LLCBuy4,48857,475$856
Q3 2016Renaissance Technologies LLCBuy52,98752,987$672

Frequently asked questions about MDGL activity

  • Which institutional owners are buying MDGL?

    Institutional owners buying MDGL include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in MDGL activity?

    "Buy" means an investor increased their reported position in MDGL compared to the prior reporting period. This reflects growing exposure to MADRIGAL PHARMACEUTICALS INC (MDGL) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in MDGL increasing?

    Institutional interest in MDGL can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.