MDGL Institutional Ownership & Shareholders
MADRIGAL PHARMACEUTICALS INC (MDGL) is currently held by 419 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $12.62B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of MDGL tracked by InsiderSet, reporting ownership valued at approximately $1.15B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $922.32M, representing an estimated loss of -19.85% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed MDGL value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Rtw Investments, Lp, Janus Henderson Group Plc, and several other long-term asset managers with concentrated positions in MADRIGAL PHARMACEUTICALS INC (MDGL).
This page ranks the largest institutional MDGL shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
419
Total Reported Value
$12.62B
Largest Holder
Baker Bros. Advisors Lp
Largest Position
$1.15B
Insider Transactions (90d)
26
Latest Filing Quarter
Q2 2026
New Institutional Positions
73
Funds Exiting Positions
1
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors Lp | 5.77% | 2,143,131 | $1,150,754,190 | $922,317,857 | -$228,436,333 | -19.85% | |
| Rtw Investments, Lp | 9.14% | 1,993,687 | $1,070,510,235 | $858,003,137 | -$212,507,098 | -19.85% | |
| Janus Henderson Group Plc | 0.52% | 2,018,647 | $1,051,727,476 | $868,744,923 | -$182,982,553 | -17.40% | |
| Avoro Capital Advisors Llc | 8.84% | 1,833,333 | $984,408,154 | $788,993,190 | -$195,414,964 | -19.85% | |
| Paulson & Co. Inc. | 27.94% | 1,340,020 | $719,523,739 | $576,691,007 | -$142,832,732 | -19.85% | |
| Blackrock, Inc. | 0.01% | 1,200,770 | $644,753,455 | $516,763,377 | -$127,990,078 | -19.85% | |
| Vanguard Capital Management Llc | 0.01% | 835,668 | $448,711,933 | $359,638,080 | -$89,073,853 | -19.85% | |
| Wellington Management Group Llp | 0.08% | 825,714 | $443,367,132 | $355,354,277 | -$88,012,855 | -19.85% | |
| Vanguard Portfolio Management Llc | 0.02% | 781,731 | $419,750,461 | $336,425,753 | -$83,324,708 | -19.85% | |
| State Street Corp | 0.01% | 527,057 | $282,995,975 | $226,824,251 | -$56,171,724 | -19.85% | |
| Citadel Advisors Llc | 0.16% | 507,233 | $272,358,759 | $218,292,794 | -$54,065,965 | -19.85% | |
| Ubs Group Ag | 0.03% | 401,708 | $215,697,110 | $172,879,055 | -$42,818,055 | -19.85% | |
| Geode Capital Management, Llc | 0.01% | 374,880 | $201,342,418 | $161,333,357 | -$40,009,061 | -19.87% | |
| Fmr Llc | 0.01% | 356,201 | $191,262,164 | $153,294,662 | -$37,967,502 | -19.85% | |
| William Blair Investment Management, Llc | 0.52% | 324,123 | $174,037,845 | $139,489,574 | -$34,548,271 | -19.85% | |
| Invesco Ltd. | 0.01% | 301,435 | $161,855,524 | $129,725,567 | -$32,129,957 | -19.85% | |
| Armistice Capital, Llc | 4.28% | 288,000 | $154,641,600 | $123,943,680 | -$30,697,920 | -19.85% | |
| Lord, Abbett & Co. Llc | 0.43% | 281,500 | $151,151,000 | $121,146,340 | -$30,004,660 | -19.85% | |
| Goldman Sachs Group Inc | 0.01% | 246,280 | $132,240,046 | $105,989,061 | -$26,250,985 | -19.85% | |
| Polar Capital Holdings Plc | 0.37% | 244,274 | $131,162,924 | $105,125,759 | -$26,037,165 | -19.85% | |
| Ameriprise Financial Inc | 0.03% | 231,205 | $124,147,079 | $99,501,384 | -$24,645,695 | -19.85% | |
| Norges Bank | 0.01% | 213,886 | $114,846,088 | $92,047,979 | -$22,798,109 | -19.85% | |
| Artisan Partners Limited Partnership | 0.18% | 210,205 | $112,869,575 | $90,463,824 | -$22,405,751 | -19.85% | |
| Pictet Asset Management Holding Sa | 0.10% | 192,896 | $103,486,147 | $83,014,723 | -$20,471,424 | -19.78% | |
| Jane Street Group, Llc | 0.07% | 191,541 | $102,847,940 | $82,431,585 | -$20,416,355 | -19.85% | |
| Price T Rowe Associates Inc | 0.01% | 187,226 | $100,532,000 | $80,574,581 | -$19,957,419 | -19.85% | |
| Alliancebernstein L.P. | 0.03% | 189,458 | $99,175,579 | $81,535,145 | -$17,640,434 | -17.79% | |
| Charles Schwab Investment Management Inc | 0.01% | 184,324 | $98,972,771 | $79,325,677 | -$19,647,094 | -19.85% | |
| Toronto Dominion Bank | 0.16% | 181,432 | $97,419,912 | $78,081,076 | -$19,338,836 | -19.85% | |
| Rock Springs Capital Management Lp | 4.59% | 174,999 | $93,965,713 | $75,312,570 | -$18,653,143 | -19.85% | |
| Hood River Capital Management Llc | 0.66% | 169,084 | $90,789,654 | $72,766,990 | -$18,022,664 | -19.85% | |
| Holocene Advisors, Lp | 0.19% | 152,924 | $82,112,542 | $65,812,373 | -$16,300,169 | -19.85% | |
| Susquehanna International Group, Llp | 0.07% | 148,610 | $79,796,140 | $63,955,800 | -$15,840,340 | -19.85% | |
| Morgan Stanley | 0.00% | 139,009 | $74,641,318 | $59,823,913 | -$14,817,405 | -19.85% | |
| Point72 Asset Management, L.P. | 0.11% | 137,029 | $73,577,722 | $58,971,800 | -$14,605,922 | -19.85% | |
| Bank Of America Corp | 0.00% | 134,036 | $71,970,631 | $57,683,733 | -$14,286,898 | -19.85% | |
| Bank Of New York Mellon Corp | 0.01% | 128,520 | $69,008,635 | $55,309,867 | -$13,698,768 | -19.85% | |
| Woodline Partners Lp | 0.21% | 125,899 | $67,601,468 | $54,181,894 | -$13,419,574 | -19.85% | |
| Vanguard Fiduciary Trust Co | 0.01% | 121,583 | $65,283,992 | $52,324,460 | -$12,959,532 | -19.85% | |
| Clearbridge Investments, Llc | 0.05% | 109,325 | $58,701,796 | $47,049,107 | -$11,652,689 | -19.85% | |
| Erste Asset Management Gmbh | 0.45% | 110,210 | $58,111,529 | $47,429,976 | -$10,681,553 | -18.38% | |
| Marshall Wace, Llp | 0.05% | 101,859 | $54,693,192 | $43,836,039 | -$10,857,153 | -19.85% | |
| Fiera Capital Corp | 0.19% | 99,857 | $53,618,216 | $42,974,459 | -$10,643,757 | -19.85% | |
| American Century Companies Inc | 0.02% | 99,396 | $53,371,576 | $42,776,063 | -$10,595,513 | -19.85% | |
| Northern Trust Corp | 0.01% | 98,510 | $52,894,944 | $42,394,764 | -$10,500,180 | -19.85% | |
| New York State Common Retirement Fund | 0.06% | 94,743 | $50,872,254 | $40,773,597 | -$10,098,657 | -19.85% | |
| Westfield Capital Management Co Lp | 0.16% | 93,931 | $50,436,250 | $40,424,145 | -$10,012,105 | -19.85% | |
| Hrt Financial Lp | 0.08% | 84,634 | $45,444,000 | $36,423,088 | -$9,020,912 | -19.85% | |
| Deutsche Bank Ag\ | 0.01% | 83,916 | $45,058,696 | $36,114,090 | -$8,944,606 | -19.85% | |
| Millennium Management Llc | 0.03% | 81,196 | $43,598,192 | $34,943,511 | -$8,654,681 | -19.85% |
Frequently asked questions about MDGL
Who are the largest institutional holders of MDGL?
The largest institutional holders of MDGL reported in the latest SEC Form 13F filings include Baker Bros. Advisors Lp, Rtw Investments, Lp, Janus Henderson Group Plc, Avoro Capital Advisors Llc, and Paulson & Co. Inc.. InsiderSet ranks institutional holders by their latest reported MDGL position.
What is MDGL institutional ownership?
This page tracks MDGL positions reported by institutional investment managers through SEC Form 13F. MADRIGAL PHARMACEUTICALS INC (MDGL) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own MDGL?
InsiderSet currently tracks 419 institutional managers reporting MDGL holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of MDGL shareholders.
How much MDGL stock do institutions own?
Institutional investment managers disclosed approximately $12.62B in MDGL holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was MDGL institutional ownership last updated?
The latest MDGL institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional MDGL holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its MDGL position after the reporting date.
Are institutions buying or selling MDGL?
Institutional buying and selling can be analyzed by comparing MDGL positions across consecutive 13F reporting periods. InsiderSet's MDGL Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View MDGL ownership changes.
How has MDGL institutional ownership changed over time?
InsiderSet tracks MDGL institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.