ORCHESTRA BIOMED HOLDINGS IN (OBIO) Institutional Ownership Changes & 13F Activity

ORCHESTRA BIOMED HOLDINGS IN (OBIO) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q1 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q1 2026Renaissance Technologies LLCSell-80,40070,900$301,325
Q4 2025Renaissance Technologies LLCSell-229,208151,300$627,895
Q3 2025Renaissance Technologies LLCBuy211,108380,508$943,660
Q2 2025Renaissance Technologies LLCBuy156,800169,400$453,992
Q2 2023Renaissance Technologies LLCBuy12,60012,600$88

Frequently asked questions about OBIO activity

  • Which institutional owners are buying OBIO?

    Institutional owners buying OBIO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in OBIO activity?

    "Buy" means an investor increased their reported position in OBIO compared to the prior reporting period. This reflects growing exposure to ORCHESTRA BIOMED HOLDINGS IN (OBIO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in OBIO increasing?

    Institutional interest in OBIO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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