PROTALIX BIOTHERAPEUTICS INC (PLX) Stock Institutional Trading Activity


PROTALIX BIOTHERAPEUTICS INC (PLX) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCSell-52,1001,263,300$2,273,940
Q3 2025Renaissance Technologies LLCSell-299,6031,315,400$2,920,188
Q2 2025Renaissance Technologies LLCBuy426,0501,615,003$2,390,204
Q1 2025Renaissance Technologies LLCBuy70,9531,188,953$3,043,720
Q4 2024Renaissance Technologies LLCBuy162,1001,118,000$2,101,840
Q3 2024Renaissance Technologies LLCBuy151,300955,900$975,018
Q2 2024Renaissance Technologies LLCSell-20,100804,600$941,382
Q1 2024Renaissance Technologies LLCBuy159,100824,700$1,039
Q4 2023Renaissance Technologies LLCBuy44,500665,600$1,185
Q3 2023Renaissance Technologies LLCSell-38,200621,100$1,031
Q2 2023Renaissance Technologies LLCSell-550,450659,300$1,319
Q1 2023Renaissance Technologies LLCBuy985,1471,209,750$2,540
Q4 2022Renaissance Technologies LLCBuy107,403224,603$308
Q3 2022Renaissance Technologies LLCBuy2,400117,200$122
Q2 2022Renaissance Technologies LLCBuy102,900114,800$125
Q1 2022Renaissance Technologies LLCSell-18,17511,900$13
Q2 2021Renaissance Technologies LLCSell-477,55930,075$57
Q1 2021Renaissance Technologies LLCBuy19,000507,634$2,264
Q4 2020Renaissance Technologies LLCSell-1,700488,634$1,774
Q3 2020Renaissance Technologies LLCSell-40,100490,334$1,898
Q2 2020Renaissance Technologies LLCBuy53,000530,434$2,010
Q1 2020Renaissance Technologies LLCBuy17,800477,434$1,122
Q4 2019Renaissance Technologies LLCBuy459,634459,634$1,508

Frequently asked questions about PLX activity

  • Which institutional owners are buying PLX?

    Institutional owners buying PLX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in PLX activity?

    "Buy" means an investor increased their reported position in PLX compared to the prior reporting period. This reflects growing exposure to PROTALIX BIOTHERAPEUTICS INC (PLX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in PLX increasing?

    Institutional interest in PLX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.