PROTALIX BIOTHERAPEUTICS INC (PLX) Top Institutional Shareholders
PROTALIX BIOTHERAPEUTICS INC (PLX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $35.73M in PLX holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of PLX tracked by InsiderSet, reporting ownership valued at approximately $7.85M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $7.31M, representing an estimated loss of -6.91% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 78% of the total disclosed PLX value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Mak Capital One Llc, Renaissance Technologies LLC, and several other long-term asset managers with concentrated positions in PROTALIX BIOTHERAPEUTICS INC (PLX).
This page ranks the largest institutional PLX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
97
Total Reported Value
$35.73M
Largest Holder
Blackrock, Inc.
Largest Position
$7.85M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
107
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 3,616,962 | $7,848,807 | $7,306,263 | -$542,544 | -6.91% | |
| Mak Capital One Llc | 1.27% | 3,544,139 | $7,690,782 | $7,159,161 | -$531,621 | -6.91% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 1,224,800 | $2,657,816 | $2,474,096 | -$183,720 | -6.91% |
| State Street Corp | 0.00% | 972,815 | $2,111,009 | $1,965,086 | -$145,923 | -6.91% | |
| Northern Trust Corp | 0.00% | 885,448 | $1,921,422 | $1,788,605 | -$132,817 | -6.91% | |
| Geode Capital Management, Llc | 0.00% | 865,298 | $1,877,696 | $1,747,902 | -$129,794 | -6.91% | |
| Stratos Wealth Partners, Ltd. | 0.01% | 500,000 | $1,085,000 | $1,010,000 | -$75,000 | -6.91% | |
| Vanguard Portfolio Management Llc | 0.00% | 432,485 | $938,492 | $873,620 | -$64,872 | -6.91% | |
| Prospera Financial Services Inc | 0.01% | 418,570 | $908,272 | $845,511 | -$62,761 | -6.91% | |
| Opaleye Management Inc. | 0.10% | 340,000 | $737,800 | $686,800 | -$51,000 | -6.91% | |
| Morgan Stanley | 0.00% | 301,793 | $654,890 | $609,622 | -$45,268 | -6.91% | |
| Dimensional Fund Advisors Lp | 0.00% | 296,843 | $643,789 | $599,623 | -$44,166 | -6.86% | |
| Ubs Group Ag | 0.00% | 265,535 | $576,211 | $536,381 | -$39,830 | -6.91% | |
| Goldman Sachs Group Inc | 0.00% | 251,345 | $545,418 | $507,717 | -$37,701 | -6.91% | |
| Bank Of New York Mellon Corp | 0.00% | 219,307 | $475,896 | $443,000 | -$32,896 | -6.91% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | 207,275 | $449,787 | $418,696 | -$31,092 | -6.91% | |
| Round Rock Advisors Llc | 0.06% | 192,080 | $416,814 | $388,002 | -$28,812 | -6.91% | |
| Bridgeway Capital Management, Llc | 0.01% | 189,100 | $410,347 | $381,982 | -$28,365 | -6.91% | |
| Evergreen Capital Management Llc | 0.01% | 171,338 | $371,804 | $346,103 | -$25,701 | -6.91% | |
| Charles Schwab Investment Management Inc | 0.00% | 159,311 | $345,705 | $321,808 | -$23,897 | -6.91% | |
| Diametric Capital, Lp | 0.07% | 124,195 | $269,503 | $250,874 | -$18,629 | -6.91% | |
| Nuveen, Llc | 0.00% | 90,188 | $195,708 | $182,180 | -$13,528 | -6.91% | |
| Lazard Asset Management Llc | 0.00% | 86,617 | $187,959 | $174,966 | -$12,993 | -6.91% | |
| Bank Of America Corp | 0.00% | 79,079 | $171,601 | $159,740 | -$11,861 | -6.91% | |
| Deutsche Bank Ag\ | 0.00% | 74,985 | $162,717 | $151,470 | -$11,247 | -6.91% | |
| Orin Green Financial, Llc | 0.06% | 64,433 | $139,820 | $130,155 | -$9,665 | -6.91% | |
| Vanguard Fiduciary Trust Co | 0.00% | 63,351 | $137,472 | $127,969 | -$9,503 | -6.91% | |
| Susquehanna International Group, Llp | 0.00% | 49,085 | $106,514 | $99,152 | -$7,362 | -6.91% | |
| Invesco Ltd. | 0.00% | 47,402 | $102,863 | $95,752 | -$7,111 | -6.91% | |
| Rhumbline Advisers | 0.00% | 45,817 | $99,420 | $92,550 | -$6,870 | -6.91% | |
| Metlife Investment Management, Llc | 0.00% | 43,697 | $94,822 | $88,268 | -$6,554 | -6.91% | |
| Phoenix Financial Ltd. | 0.00% | 40,000 | $86,740 | $80,800 | -$5,940 | -6.85% | |
| Mirae Asset Global Etfs Holdings Ltd. | 0.00% | 34,062 | $73,915 | $68,805 | -$5,110 | -6.91% | |
| New York State Common Retirement Fund | 0.00% | 31,100 | $67,487 | $62,822 | -$4,665 | -6.91% | |
| Aqr Capital Management Llc | 0.00% | 30,493 | $66,169 | $61,596 | -$4,573 | -6.91% | |
| Aptus Capital Advisors, Llc | 0.00% | 27,231 | $59,091 | $55,007 | -$4,084 | -6.91% | |
| Wells Fargo & Company/Mn | 0.00% | 26,522 | $57,553 | $53,574 | -$3,979 | -6.91% | |
| Earned Wealth Advisors, Llc | 0.00% | 26,051 | $56,531 | $52,623 | -$3,908 | -6.91% | |
| Smartleaf Asset Management Llc | 0.00% | 25,975 | $54,288 | $52,470 | -$1,819 | -3.35% | |
| Simplex Trading, Llc | 0.00% | 22,671 | $49,196 | $45,795 | -$3,401 | -6.91% | |
| Intech Investment Management Llc | 0.00% | 19,958 | $43,309 | $40,315 | -$2,994 | -6.91% | |
| Manufacturers Life Insurance Company, The | 0.00% | 19,528 | $42,376 | $39,447 | -$2,929 | -6.91% | |
| Commonwealth Equity Services, Llc | 0.00% | 19,461 | $42,230 | $39,311 | -$2,919 | -6.91% | |
| Prelude Capital Management, Llc | 0.00% | 18,900 | $41,013 | $38,178 | -$2,835 | -6.91% | |
| Police & Firemen'S Retirement System Of New Jersey | 0.00% | 18,554 | $40,262 | $37,479 | -$2,783 | -6.91% | |
| Two Sigma Investments, Lp | 0.00% | 18,129 | $39,340 | $36,621 | -$2,719 | -6.91% | |
| Bnp Paribas Financial Markets | 0.00% | 17,343 | $37,634 | $35,033 | -$2,601 | -6.91% | |
| Jane Street Group, Llc | 0.00% | 17,342 | $37,632 | $35,031 | -$2,601 | -6.91% | |
| Lido Advisors, Llc | 0.00% | 15,554 | $33,752 | $31,419 | -$2,333 | -6.91% | |
| Barclays Plc | 0.00% | 14,822 | $32,164 | $29,940 | -$2,224 | -6.91% |
Frequently asked questions about PLX
Who owns the most PLX stock?
The largest holders of PLX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for PROTALIX BIOTHERAPEUTICS INC (PLX).
Is PLX widely held by superinvestors?
Many widely followed stocks like PLX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly PLX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.