PRIME MEDICINE INC (PRME) Institutional Ownership

PRME is currently held by 3 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $24.36M based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026.

The largest disclosed holder is ARK Invest, which reported ownership valued at approximately $21.74M in its March 31, 2026 13F filing. Based on current market prices and the latest disclosed share count, ARK Invest's PRME position is now estimated to be worth approximately $19.74M, representing an estimated loss of -9.20% since the filing period.

Major shareholders tracked on this page include ARK Invest, Renaissance Technologies LLC, Sequoia Financial Advisors, and other prominent asset managers. Collectively, these investors account for approximately 100% of the total disclosed value among the investors covered in this analysis.

This page tracks 13F-reported ownership trends, hedge fund exposure, portfolio concentration, historical 13F filings, and estimated holding performance to help investors analyze smart money sentiment toward PRIME MEDICINE INC (PRME).

Institutional Ownership Trend

Portfolio quarterInstitutional holdersTotal reported valueTotal shares
Q1 20263$24,358,3966,999,539
Q4 20252$22,616,3666,517,685
Q3 20252$36,633,3676,612,521
Q2 20252$6,288,7902,546,069
Q1 20252$7,050,1163,542,772
Q4 20241$15,038,6815,150,233
Q3 20242$21,984,3825,680,719
Q2 20241$31,491,6136,126,773
Q1 20242$41,956,0126,355,754
Q4 20232$27,805,5453,191,562
Q3 20231$25,017,9772,622,429
Q2 20231$35,880,7712,449,199

Related PRME Institutional Insights:

PRME Institutional Ownership and 13F Activity Q1 2026 | InsiderSet