XENCOR INC (XNCR) Institutional Buying Activity

Institutional investors tracked by InsiderSet increased exposure to XENCOR INC (XNCR) during the quarter ended March 31, 2026 through a combination of new purchases and expanded existing positions disclosed in SEC Form 13F filings.

The largest institutional buyer of XNCR during the latest reporting period was Renaissance Technologies LLC, which increased its reported XNCR position by approximately $1.58M based on quarter-end filing values. Several additional hedge funds and long-term asset managers also reported meaningful increases in XNCR exposure during the quarter.

Institutional buying activity can provide insight into investor conviction, sector allocation trends, and smart money positioning toward XENCOR INC (XNCR). InsiderSet tracks quarterly accumulation trends, new institutional positions, ownership increases, and estimated performance of newly disclosed holdings using SEC filing data and recent market prices.

The investors highlighted on this page collectively added approximately $2.94M in reported XNCR exposure during the latest filing period, reflecting continued institutional interest in XENCOR INC's growth initiatives and strategic positioning.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q3 2025Renaissance Technologies LLCBuy134,789190,389$2,233,263
Q1 2025Renaissance Technologies LLCBuy87,077152,400$1,621,536
Q2 2024Renaissance Technologies LLCBuy21,72365,323$1,236,564
Q4 2023Renaissance Technologies LLCBuy136,000180,300$3,828
Q2 2023Renaissance Technologies LLCBuy16,273128,273$3,203
Q1 2023Renaissance Technologies LLCBuy8,700112,000$3,124
Q1 2022Renaissance Technologies LLCBuy176,700234,900$6,267
Q2 2021Renaissance Technologies LLCBuy66,800139,100$4,798
Q1 2021Renaissance Technologies LLCBuy64,25672,300$3,113
Q2 2019Renaissance Technologies LLCBuy17,00030,500$1,248
Q4 2017Renaissance Technologies LLCBuy56,400156,000$3,420
Q3 2017Renaissance Technologies LLCBuy59,92899,600$2,283
Q3 2015Renaissance Technologies LLCBuy150,353150,353$1,839

Frequently asked questions about XNCR activity

  • Which institutional owners are buying XNCR?

    Institutional owners buying XNCR include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in XNCR activity?

    "Buy" means an investor increased their reported position in XNCR compared to the prior reporting period. This reflects growing exposure to XENCOR INC (XNCR) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in XNCR increasing?

    Institutional interest in XNCR can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.