ZYME (ZYME) Institutional Ownership Changes & 13F Activity

ZYME (ZYME) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCSell-210,823220,877$5,815,691
Q3 2025Renaissance Technologies LLCSell-101,600431,700$7,373,436
Q2 2025Renaissance Technologies LLCBuy82,700533,300$6,692,915
Q1 2025Renaissance Technologies LLCBuy164,900450,600$5,366,646
Q4 2024Renaissance Technologies LLCBuy101,100285,700$4,182,648
Q3 2024Renaissance Technologies LLCSell-52,181184,600$2,316,730
Q2 2024Renaissance Technologies LLCBuy121,181236,781$2,015,006
Q1 2024Renaissance Technologies LLCBuy100,900115,600$1,216
Q4 2023Renaissance Technologies LLCSell-1,15814,700$153
Q3 2023Renaissance Technologies LLCSell-246,27915,858$101
Q2 2023Renaissance Technologies LLCBuy178,737262,137$2,265
Q1 2023Renaissance Technologies LLCSell-36,60083,400$754
Q4 2022Renaissance Technologies LLCBuy120,000120,000$943

Frequently asked questions about ZYME activity

  • Which institutional owners are buying ZYME?

    Institutional owners buying ZYME include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in ZYME activity?

    "Buy" means an investor increased their reported position in ZYME compared to the prior reporting period. This reflects growing exposure to ZYME rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in ZYME increasing?

    Institutional interest in ZYME can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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