AGIO Institutional Ownership & Shareholders
AGIOS PHARMACEUTICALS INC (AGIO) is currently held by 237 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $2.28B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of AGIO tracked by InsiderSet, reporting ownership valued at approximately $239.58M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $197.23M, representing an estimated loss of -17.68% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 50% of the total disclosed AGIO value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., State Street Corp, Lynx1 Capital Management Lp, and several other long-term asset managers with concentrated positions in AGIOS PHARMACEUTICALS INC (AGIO).
This page ranks the largest institutional AGIO shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
237
Total Reported Value
$2.28B
Largest Holder
Blackrock, Inc.
Largest Position
$239.58M
Insider Transactions (90d)
4
Latest Filing Quarter
Q2 2026
New Institutional Positions
50
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 6,455,997 | $239,582,050 | $197,230,708 | -$42,351,342 | -17.68% | |
| State Street Corp | 0.00% | 3,533,633 | $131,144,972 | $107,952,488 | -$23,192,484 | -17.68% | |
| Lynx1 Capital Management Lp | 14.62% | 3,408,937 | $126,505,652 | $104,143,025 | -$22,362,627 | -17.68% | |
| D. E. Shaw & Co., Inc. | 0.07% | 3,107,005 | $115,300,956 | $94,919,003 | -$20,381,953 | -17.68% | |
| Vanguard Portfolio Management Llc | 0.00% | 2,898,197 | $107,552,091 | $88,539,918 | -$19,012,173 | -17.68% | |
| Vanguard Capital Management Llc | 0.00% | 2,681,845 | $99,523,268 | $81,930,365 | -$17,592,903 | -17.68% | |
| Armistice Capital, Llc | 2.46% | 2,400,000 | $89,064,000 | $73,320,000 | -$15,744,000 | -17.68% | |
| Erste Asset Management Gmbh | 0.64% | 2,154,900 | $81,972,396 | $65,832,195 | -$16,140,201 | -19.69% | |
| Nomura Asset Management International Inc. | 0.12% | 2,110,809 | $78,332,000 | $64,485,215 | -$13,846,785 | -17.68% | |
| Assenagon Asset Management S.A. | 0.06% | 1,886,412 | $62,723,199 | $57,629,887 | -$5,093,312 | -8.12% | |
| Geode Capital Management, Llc | 0.00% | 1,574,268 | $58,433,490 | $48,093,887 | -$10,339,603 | -17.69% | |
| Susquehanna International Group, Llp | 0.05% | 1,375,558 | $51,046,957 | $42,023,297 | -$9,023,660 | -17.68% | |
| Adar1 Capital Management, Llc | 2.25% | 1,288,053 | $47,799,647 | $39,350,019 | -$8,449,628 | -17.68% | |
| Bnp Paribas Asset Management Holding S.A. | 0.05% | 1,280,044 | $47,502,433 | $39,105,344 | -$8,397,089 | -17.68% | |
| Dimensional Fund Advisors Lp | 0.01% | 1,248,738 | $46,345,467 | $38,148,946 | -$8,196,521 | -17.69% | |
| Gw&K Investment Management, Llc | 0.35% | 1,206,615 | $44,777,000 | $36,862,088 | -$7,914,912 | -17.68% | |
| Goldman Sachs Group Inc | 0.00% | 1,150,932 | $42,711,087 | $35,160,973 | -$7,550,114 | -17.68% | |
| Ubs Group Ag | 0.01% | 985,831 | $36,584,189 | $30,117,137 | -$6,467,052 | -17.68% | |
| Morgan Stanley | 0.00% | 963,256 | $35,746,487 | $29,427,471 | -$6,319,016 | -17.68% | |
| Nuveen, Llc | 0.01% | 873,560 | $32,417,811 | $26,687,258 | -$5,730,553 | -17.68% | |
| Arrowstreet Capital, Limited Partnership | 0.01% | 810,530 | $30,078,768 | $24,761,692 | -$5,317,077 | -17.68% | |
| Foresite Capital Management Vi Llc | 4.53% | 785,000 | $29,131,350 | $23,981,750 | -$5,149,600 | -17.68% | |
| Citadel Advisors Llc | 0.02% | 732,687 | $27,190,015 | $22,383,588 | -$4,806,427 | -17.68% | |
| Aqr Capital Management Llc | 0.01% | 684,340 | $25,395,858 | $20,906,587 | -$4,489,271 | -17.68% | |
| Parkman Healthcare Partners Llc | 2.55% | 669,046 | $24,828,297 | $20,439,355 | -$4,388,942 | -17.68% | |
| Scs Capital Management Llc | 0.21% | 612,850 | $22,742,864 | $18,722,568 | -$4,020,297 | -17.68% | |
| Qube Research & Technologies Ltd | 0.02% | 597,638 | $22,178,346 | $18,257,841 | -$3,920,505 | -17.68% | |
| Northern Trust Corp | 0.00% | 554,709 | $20,585,250 | $16,946,360 | -$3,638,890 | -17.68% | |
| Defilade Capital Management, L.P. | 2.72% | 546,848 | $20,293,529 | $16,706,206 | -$3,587,323 | -17.68% | |
| Charles Schwab Investment Management Inc | 0.00% | 538,128 | $19,969,930 | $16,439,810 | -$3,530,120 | -17.68% | |
| Two Sigma Investments, Lp | 0.01% | 536,380 | $19,905,062 | $16,386,409 | -$3,518,653 | -17.68% | |
| Rock Springs Capital Management Lp | 0.96% | 532,563 | $19,763,413 | $16,269,800 | -$3,493,613 | -17.68% | |
| Schonfeld Strategic Advisors Llc | 0.10% | 520,083 | $19,300,279 | $15,888,536 | -$3,411,743 | -17.68% | |
| Bank Of America Corp | 0.00% | 507,869 | $18,847,034 | $15,515,398 | -$3,331,636 | -17.68% | |
| Point72 Asset Management, L.P. | 0.03% | 506,344 | $18,790,426 | $15,468,809 | -$3,321,617 | -17.68% | |
| Jane Street Group, Llc | 0.01% | 492,598 | $18,280,312 | $15,048,869 | -$3,231,443 | -17.68% | |
| Legal & General Group Plc | 0.00% | 434,719 | $16,132,422 | $13,280,665 | -$2,851,757 | -17.68% | |
| Vanguard Fiduciary Trust Co | 0.00% | 395,868 | $14,690,661 | $12,093,767 | -$2,596,894 | -17.68% | |
| Panagora Asset Management Inc | 0.04% | 373,931 | $13,876,579 | $11,423,592 | -$2,452,987 | -17.68% | |
| Kennedy Capital Management Llc | 0.25% | 373,230 | $13,850,565 | $11,402,177 | -$2,448,389 | -17.68% | |
| Jpmorgan Chase & Co | 0.00% | 359,756 | $13,783,528 | $10,990,546 | -$2,792,982 | -20.26% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | 359,550 | $13,342,901 | $10,984,253 | -$2,358,649 | -17.68% | |
| Squarepoint Ops Llc | 0.02% | 321,138 | $11,917,431 | $9,810,766 | -$2,106,665 | -17.68% | |
| Bnp Paribas Financial Markets | 0.01% | 269,383 | $9,996,803 | $8,229,651 | -$1,767,152 | -17.68% | |
| Algert Global Llc | 0.11% | 248,007 | $9,203,540 | $7,576,614 | -$1,626,926 | -17.68% | |
| Price T Rowe Associates Inc | 0.00% | 218,966 | $8,127,000 | $6,689,411 | -$1,437,589 | -17.69% | |
| Palo Alto Investors Lp | 1.10% | 213,601 | $7,926,733 | $6,525,511 | -$1,401,222 | -17.68% | |
| Tetragon Partners Gp Ltd | 1.24% | 205,579 | $7,629,037 | $6,280,438 | -$1,348,599 | -17.68% | |
| Bank Of New York Mellon Corp | 0.00% | 198,685 | $7,373,215 | $6,069,827 | -$1,303,388 | -17.68% | |
| Jump Financial, Llc | 0.06% | 182,773 | $6,782,706 | $5,583,715 | -$1,198,991 | -17.68% |
Frequently asked questions about AGIO
Who are the largest institutional holders of AGIO?
The largest institutional holders of AGIO reported in the latest SEC Form 13F filings include Blackrock, Inc., State Street Corp, Lynx1 Capital Management Lp, D. E. Shaw & Co., Inc., and Vanguard Portfolio Management Llc. InsiderSet ranks institutional holders by their latest reported AGIO position.
What is AGIO institutional ownership?
This page tracks AGIO positions reported by institutional investment managers through SEC Form 13F. AGIOS PHARMACEUTICALS INC (AGIO) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own AGIO?
InsiderSet currently tracks 237 institutional managers reporting AGIO holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of AGIO shareholders.
How much AGIO stock do institutions own?
Institutional investment managers disclosed approximately $2.28B in AGIO holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was AGIO institutional ownership last updated?
The latest AGIO institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional AGIO holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its AGIO position after the reporting date.
Are institutions buying or selling AGIO?
Institutional buying and selling can be analyzed by comparing AGIO positions across consecutive 13F reporting periods. InsiderSet's AGIO Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View AGIO ownership changes.
How has AGIO institutional ownership changed over time?
InsiderSet tracks AGIO institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.