AGIOS PHARMACEUTICALS INC (AGIO) Institutional Shareholders
AGIOS PHARMACEUTICALS INC (AGIO) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $2.22B in AGIO holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of AGIO tracked by InsiderSet, reporting ownership valued at approximately $239.58M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $212.73M, representing an estimated loss of -11.21% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 51% of the total disclosed AGIO value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., State Street Corp, Lynx1 Capital Management Lp, and several other long-term asset managers with concentrated positions in AGIOS PHARMACEUTICALS INC (AGIO).
This page ranks the largest institutional AGIO shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
230
Total Reported Value
$2.22B
Largest Holder
Blackrock, Inc.
Largest Position
$239.58M
Insider Transactions (90d)
4
Latest Filing Quarter
Q2 2026
New Institutional Positions
49
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 6,455,997 | $239,582,050 | $212,725,101 | -$26,856,949 | -11.21% | |
| State Street Corp | 0.00% | 3,533,633 | $131,144,972 | $116,433,207 | -$14,711,765 | -11.22% | |
| Lynx1 Capital Management Lp | 14.62% | 3,408,937 | $126,505,652 | $112,324,474 | -$14,181,178 | -11.21% | |
| D. E. Shaw & Co., Inc. | 0.07% | 3,107,005 | $115,300,956 | $102,375,815 | -$12,925,141 | -11.21% | |
| Vanguard Portfolio Management Llc | 0.00% | 2,898,197 | $107,552,091 | $95,495,591 | -$12,056,500 | -11.21% | |
| Vanguard Capital Management Llc | 0.00% | 2,681,845 | $99,523,268 | $88,366,793 | -$11,156,475 | -11.21% | |
| Armistice Capital, Llc | 2.46% | 2,400,000 | $89,064,000 | $79,080,000 | -$9,984,000 | -11.21% | |
| Erste Asset Management Gmbh | 0.64% | 2,154,900 | $81,972,396 | $71,003,955 | -$10,968,441 | -13.38% | |
| Nomura Asset Management International Inc. | 0.12% | 2,110,809 | $78,332,000 | $69,551,157 | -$8,780,843 | -11.21% | |
| Geode Capital Management, Llc | 0.00% | 1,574,268 | $58,433,490 | $51,872,131 | -$6,561,359 | -11.23% | |
| Susquehanna International Group, Llp | 0.05% | 1,375,558 | $51,046,957 | $45,324,636 | -$5,722,321 | -11.21% | |
| Adar1 Capital Management, Llc | 2.25% | 1,288,053 | $47,799,647 | $42,441,346 | -$5,358,301 | -11.21% | |
| Bnp Paribas Asset Management Holding S.A. | 0.05% | 1,280,044 | $47,502,433 | $42,177,450 | -$5,324,983 | -11.21% | |
| Dimensional Fund Advisors Lp | 0.01% | 1,248,738 | $46,345,467 | $41,145,917 | -$5,199,550 | -11.22% | |
| Gw&K Investment Management, Llc | 0.35% | 1,206,615 | $44,777,000 | $39,757,964 | -$5,019,036 | -11.21% | |
| Goldman Sachs Group Inc | 0.00% | 1,150,932 | $42,711,087 | $37,923,209 | -$4,787,878 | -11.21% | |
| Ubs Group Ag | 0.01% | 985,831 | $36,584,189 | $32,483,131 | -$4,101,058 | -11.21% | |
| Morgan Stanley | 0.00% | 963,256 | $35,746,487 | $31,739,285 | -$4,007,202 | -11.21% | |
| Nuveen, Llc | 0.01% | 873,560 | $32,417,811 | $28,783,802 | -$3,634,009 | -11.21% | |
| Arrowstreet Capital, Limited Partnership | 0.01% | 810,530 | $30,078,768 | $26,706,964 | -$3,371,804 | -11.21% | |
| Foresite Capital Management Vi Llc | 4.53% | 785,000 | $29,131,350 | $25,865,750 | -$3,265,600 | -11.21% | |
| Citadel Advisors Llc | 0.02% | 732,687 | $27,190,015 | $24,142,037 | -$3,047,978 | -11.21% | |
| Aqr Capital Management Llc | 0.01% | 684,340 | $25,395,858 | $22,549,003 | -$2,846,855 | -11.21% | |
| Parkman Healthcare Partners Llc | 2.55% | 669,046 | $24,828,297 | $22,045,066 | -$2,783,231 | -11.21% | |
| Scs Capital Management Llc | 0.21% | 612,850 | $22,742,864 | $20,193,408 | -$2,549,457 | -11.21% | |
| Qube Research & Technologies Ltd | 0.02% | 597,638 | $22,178,346 | $19,692,172 | -$2,486,174 | -11.21% | |
| Northern Trust Corp | 0.00% | 554,709 | $20,585,250 | $18,277,662 | -$2,307,588 | -11.21% | |
| Defilade Capital Management, L.P. | 2.72% | 546,848 | $20,293,529 | $18,018,642 | -$2,274,887 | -11.21% | |
| Charles Schwab Investment Management Inc | 0.00% | 538,128 | $19,969,930 | $17,731,318 | -$2,238,612 | -11.21% | |
| Two Sigma Investments, Lp | 0.01% | 536,380 | $19,905,062 | $17,673,721 | -$2,231,341 | -11.21% | |
| Rock Springs Capital Management Lp | 0.96% | 532,563 | $19,763,413 | $17,547,951 | -$2,215,462 | -11.21% | |
| Schonfeld Strategic Advisors Llc | 0.10% | 520,083 | $19,300,279 | $17,136,735 | -$2,163,544 | -11.21% | |
| Bank Of America Corp | 0.00% | 507,869 | $18,847,034 | $16,734,284 | -$2,112,750 | -11.21% | |
| Point72 Asset Management, L.P. | 0.03% | 506,344 | $18,790,426 | $16,684,035 | -$2,106,391 | -11.21% | |
| Jane Street Group, Llc | 0.01% | 492,598 | $18,280,312 | $16,231,104 | -$2,049,208 | -11.21% | |
| Legal & General Group Plc | 0.00% | 434,719 | $16,132,422 | $14,323,991 | -$1,808,431 | -11.21% | |
| Vanguard Fiduciary Trust Co | 0.00% | 395,868 | $14,690,661 | $13,043,851 | -$1,646,810 | -11.21% | |
| Panagora Asset Management Inc | 0.04% | 373,931 | $13,876,579 | $12,321,026 | -$1,555,553 | -11.21% | |
| Kennedy Capital Management Llc | 0.25% | 373,230 | $13,850,565 | $12,297,929 | -$1,552,636 | -11.21% | |
| Jpmorgan Chase & Co | 0.00% | 359,756 | $13,783,528 | $11,853,960 | -$1,929,568 | -14.00% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | 359,550 | $13,342,901 | $11,847,173 | -$1,495,728 | -11.21% | |
| Squarepoint Ops Llc | 0.02% | 321,138 | $11,917,431 | $10,581,497 | -$1,335,934 | -11.21% | |
| Bnp Paribas Financial Markets | 0.01% | 269,383 | $9,996,803 | $8,876,170 | -$1,120,633 | -11.21% | |
| Algert Global Llc | 0.11% | 248,007 | $9,203,540 | $8,171,831 | -$1,031,709 | -11.21% | |
| Price T Rowe Associates Inc | 0.00% | 218,966 | $8,127,000 | $7,214,930 | -$912,070 | -11.22% | |
| Palo Alto Investors Lp | 1.10% | 213,601 | $7,926,733 | $7,038,153 | -$888,580 | -11.21% | |
| Tetragon Partners Gp Ltd | 1.24% | 205,579 | $7,629,037 | $6,773,828 | -$855,209 | -11.21% | |
| Bank Of New York Mellon Corp | 0.00% | 198,685 | $7,373,215 | $6,546,671 | -$826,544 | -11.21% | |
| Jump Financial, Llc | 0.06% | 182,773 | $6,782,706 | $6,022,370 | -$760,336 | -11.21% | |
| Invesco Ltd. | 0.00% | 168,153 | $6,240,157 | $5,540,641 | -$699,516 | -11.21% |
Frequently asked questions about AGIO
Who owns the most AGIO stock?
The largest holders of AGIO are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for AGIOS PHARMACEUTICALS INC (AGIO).
Is AGIO widely held by superinvestors?
Many widely followed stocks like AGIO appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly AGIO is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.