AGIOS PHARMACEUTICALS INC (AGIO) Institutional Shareholders
AGIOS PHARMACEUTICALS INC (AGIO) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $1.99B in AGIO holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of AGIO tracked by InsiderSet, reporting ownership valued at approximately $194.69M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $172.76M, representing an estimated loss of -11.26% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 54% of the total disclosed AGIO value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Farallon Capital Management Llc, State Street Corp, and several other long-term asset managers with concentrated positions in AGIOS PHARMACEUTICALS INC (AGIO).
This page ranks the largest institutional AGIO shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
228
Total Reported Value
$1.99B
Largest Holder
Blackrock, Inc.
Largest Position
$194.69M
Insider Transactions (90d)
13
Latest Filing Quarter
Q2 2026
New Institutional Positions
109
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 5,754,957 | $194,690,195 | $172,763,809 | -$21,926,386 | -11.26% | |
| Farallon Capital Management Llc | 1.25% | 5,684,000 | $192,289,720 | $170,633,680 | -$21,656,040 | -11.26% | |
| State Street Corp | 0.00% | 3,364,879 | $113,719,376 | $101,013,668 | -$12,705,708 | -11.17% | |
| Armistice Capital, Llc | 3.03% | 2,716,000 | $91,882,280 | $81,534,320 | -$10,347,960 | -11.26% | |
| D. E. Shaw & Co., Inc. | 0.07% | 2,681,169 | $90,703,947 | $80,488,693 | -$10,215,254 | -11.26% | |
| Vanguard Capital Management Llc | 0.00% | 2,632,316 | $89,051,250 | $79,022,126 | -$10,029,124 | -11.26% | |
| Lynx1 Capital Management Lp | 13.96% | 2,611,568 | $88,349,345 | $78,399,271 | -$9,950,074 | -11.26% | |
| Vanguard Portfolio Management Llc | 0.00% | 2,611,035 | $88,331,314 | $78,383,271 | -$9,948,043 | -11.26% | |
| Erste Asset Management Gmbh | 0.64% | 2,154,900 | $81,972,396 | $64,690,098 | -$17,282,298 | -21.08% | |
| Bnp Paribas Asset Management Holding S.A. | 0.06% | 1,580,840 | $53,479,817 | $47,456,817 | -$6,023,000 | -11.26% | |
| Nomura Asset Management International Inc. | 0.09% | 1,494,435 | $50,557,000 | $44,862,939 | -$5,694,061 | -11.26% | |
| Geode Capital Management, Llc | 0.00% | 1,467,910 | $49,670,160 | $44,066,658 | -$5,603,502 | -11.28% | |
| Susquehanna International Group, Llp | 0.06% | 1,344,953 | $45,499,760 | $40,375,489 | -$5,124,271 | -11.26% | |
| Mpm Bioimpact Llc | 3.41% | 1,306,261 | $44,190,810 | $39,213,955 | -$4,976,855 | -11.26% | |
| Frazier Life Sciences Management, L.P. | 1.09% | 1,256,080 | $42,493,186 | $37,707,522 | -$4,785,664 | -11.26% | |
| Dimensional Fund Advisors Lp | 0.01% | 1,151,614 | $38,940,060 | $34,571,452 | -$4,368,608 | -11.22% | |
| Morgan Stanley | 0.00% | 967,525 | $32,731,410 | $29,045,101 | -$3,686,310 | -11.26% | |
| Goldman Sachs Group Inc | 0.00% | 805,776 | $27,259,402 | $24,189,396 | -$3,070,006 | -11.26% | |
| Rock Springs Capital Management Lp | 1.59% | 799,163 | $27,035,684 | $23,990,873 | -$3,044,811 | -11.26% | |
| Nuveen, Llc | 0.01% | 722,348 | $24,437,033 | $21,684,887 | -$2,752,146 | -11.26% | |
| Jane Street Group, Llc | 0.02% | 685,240 | $23,181,669 | $20,570,905 | -$2,610,764 | -11.26% | |
| Wellington Management Group Llp | 0.00% | 641,486 | $21,701,472 | $19,257,410 | -$2,444,062 | -11.26% | |
| Citadel Advisors Llc | 0.01% | 619,613 | $20,961,508 | $18,600,782 | -$2,360,726 | -11.26% | |
| Scs Capital Management Llc | 0.22% | 612,850 | $20,732,716 | $18,397,757 | -$2,334,959 | -11.26% | |
| Foresite Capital Management Vi Llc | 3.86% | 525,000 | $17,760,750 | $15,760,500 | -$2,000,250 | -11.26% | |
| Northern Trust Corp | 0.00% | 509,272 | $17,228,672 | $15,288,345 | -$1,940,327 | -11.26% | |
| Bank Of America Corp | 0.00% | 507,900 | $17,182,243 | $15,247,158 | -$1,935,085 | -11.26% | |
| Artisan Partners Limited Partnership | 0.03% | 481,516 | $16,289,686 | $14,455,110 | -$1,834,576 | -11.26% | |
| Charles Schwab Investment Management Inc | 0.00% | 477,032 | $16,137,993 | $14,320,501 | -$1,817,492 | -11.26% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | 450,093 | $15,226,646 | $13,511,792 | -$1,714,854 | -11.26% | |
| Vestal Point Capital, Lp | 0.43% | 450,000 | $15,223,500 | $13,509,000 | -$1,714,500 | -11.26% | |
| Marshall Wace, Llp | 0.02% | 448,118 | $15,159,832 | $13,452,502 | -$1,707,330 | -11.26% | |
| Legal & General Group Plc | 0.00% | 423,915 | $14,341,046 | $12,725,928 | -$1,615,118 | -11.26% | |
| Arrowmark Colorado Holdings Llc | 0.36% | 403,590 | $13,653,450 | $12,115,772 | -$1,537,678 | -11.26% | |
| Parkman Healthcare Partners Llc | 1.42% | 403,525 | $13,651,251 | $12,113,821 | -$1,537,431 | -11.26% | |
| Vanguard Fiduciary Trust Co | 0.00% | 382,021 | $12,923,770 | $11,468,270 | -$1,455,500 | -11.26% | |
| Bnp Paribas Financial Markets | 0.01% | 327,457 | $11,077,870 | $9,830,259 | -$1,247,611 | -11.26% | |
| Kennedy Capital Management Llc | 0.20% | 275,456 | $9,318,676 | $8,269,189 | -$1,049,487 | -11.26% | |
| Two Sigma Investments, Lp | 0.01% | 251,636 | $8,512,846 | $7,554,113 | -$958,733 | -11.26% | |
| Arrowstreet Capital, Limited Partnership | 0.00% | 250,461 | $8,473,096 | $7,518,839 | -$954,257 | -11.26% | |
| Panagora Asset Management Inc | 0.03% | 238,468 | $8,067,372 | $7,158,809 | -$908,563 | -11.26% | |
| Palo Alto Investors Lp | 1.11% | 213,601 | $7,226,122 | $6,412,302 | -$813,820 | -11.26% | |
| Seven Fleet Capital Management Lp | 2.25% | 209,547 | $7,088,975 | $6,290,601 | -$798,374 | -11.26% | |
| Squarepoint Ops Llc | 0.02% | 208,888 | $7,066,681 | $6,270,818 | -$795,863 | -11.26% | |
| Schonfeld Strategic Advisors Llc | 0.06% | 200,061 | $6,768,062 | $6,005,831 | -$762,231 | -11.26% | |
| Eversept Partners, Lp | 0.45% | 200,000 | $6,766,000 | $6,004,000 | -$762,000 | -11.26% | |
| Qube Research & Technologies Ltd | 0.01% | 187,667 | $6,348,775 | $5,633,763 | -$715,012 | -11.26% | |
| Bank Of New York Mellon Corp | 0.00% | 186,791 | $6,319,154 | $5,607,466 | -$711,688 | -11.26% | |
| Group One Trading Llc | 0.19% | 173,279 | $5,862,029 | $5,201,836 | -$660,193 | -11.26% | |
| Tetragon Partners Gp Ltd | 1.10% | 164,839 | $5,576,503 | $4,948,467 | -$628,036 | -11.26% |
Frequently asked questions about AGIO
Who owns the most AGIO stock?
The largest holders of AGIO are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for AGIOS PHARMACEUTICALS INC (AGIO).
Is AGIO widely held by superinvestors?
Many widely followed stocks like AGIO appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly AGIO is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.