ALNY Institutional Ownership & Shareholders
ALNYLAM PHARMACEUTICALS INC (ALNY) is currently held by 759 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $41.69B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Fmr Llc is currently the largest disclosed institutional shareholder of ALNY tracked by InsiderSet, reporting ownership valued at approximately $4.52B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $2.48B, representing an estimated loss of -45.19% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 58% of the total disclosed ALNY value among the investors covered in this analysis. Major shareholders include Fmr Llc, Capital World Investors, Blackrock, Inc., and several other long-term asset managers with concentrated positions in ALNYLAM PHARMACEUTICALS INC (ALNY).
This page ranks the largest institutional ALNY shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
759
Total Reported Value
$41.69B
Largest Holder
Fmr Llc
Largest Position
$4.52B
Insider Transactions (90d)
2
Latest Filing Quarter
Q2 2026
New Institutional Positions
41
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.20% | 15,023,962 | $4,522,663,249 | $2,478,953,730 | -$2,043,709,519 | -45.19% | |
| Capital World Investors | 0.40% | 11,144,846 | $3,354,715,611 | $1,838,899,590 | -$1,515,816,021 | -45.18% | |
| Blackrock, Inc. | 0.05% | 10,907,675 | $3,283,537,489 | $1,799,766,375 | -$1,483,771,114 | -45.19% | |
| Capital Research Global Investors | 0.41% | 9,750,699 | $2,935,115,324 | $1,608,865,335 | -$1,326,249,989 | -45.19% | |
| Banque Cantonale Vaudoise | 0.30% | 7,303 | $2,198,000,000 | $1,204,995 | -$2,196,795,005 | -99.95% | |
| Vanguard Portfolio Management Llc | 0.09% | 6,538,390 | $1,968,251,542 | $1,078,834,350 | -$889,417,192 | -45.19% | |
| Vanguard Capital Management Llc | 0.04% | 6,029,478 | $1,815,053,762 | $994,863,870 | -$820,189,892 | -45.19% | |
| T. Rowe Price Investment Management, Inc. | 1.11% | 5,642,173 | $1,698,464,000 | $930,958,545 | -$767,505,455 | -45.19% | |
| Invesco Ltd. | 0.09% | 3,754,318 | $1,130,162,348 | $619,462,470 | -$510,699,878 | -45.19% | |
| State Street Corp | 0.03% | 3,555,689 | $1,070,369,060 | $586,688,685 | -$483,680,375 | -45.19% | |
| Geode Capital Management, Llc | 0.04% | 2,635,840 | $791,345,610 | $434,913,600 | -$356,432,010 | -45.04% | |
| Jpmorgan Chase & Co | 0.05% | 2,675,517 | $785,318,336 | $441,460,305 | -$343,858,031 | -43.79% | |
| Baillie Gifford & Co | 0.67% | 2,439,889 | $734,479,786 | $402,581,685 | -$331,898,101 | -45.19% | |
| Norges Bank | 0.07% | 2,271,813 | $683,883,867 | $374,849,145 | -$309,034,722 | -45.19% | |
| Wellington Management Group Llp | 0.11% | 2,110,407 | $635,295,819 | $348,217,155 | -$287,078,664 | -45.19% | |
| Orbis Allan Gray Ltd | 2.06% | 1,987,407 | $598,269,130 | $327,922,155 | -$270,346,975 | -45.19% | |
| Dodge & Cox Stock Fund | V. D. Dodge, E. M. Cox | 0.31% | 1,955,393 | $588,631,955 | $322,639,845 | -$265,992,110 | -45.19% |
| Two Sigma Investments, Lp | 0.42% | 1,875,937 | $564,713,315 | $309,529,605 | -$255,183,710 | -45.19% | |
| American Century Companies Inc | 0.25% | 1,853,956 | $558,098,292 | $305,902,740 | -$252,195,552 | -45.19% | |
| Clearbridge Investments, Llc | 0.31% | 1,259,483 | $379,142,285 | $207,814,695 | -$171,327,590 | -45.19% | |
| Price T Rowe Associates Inc | 0.03% | 1,149,201 | $345,945,000 | $189,618,165 | -$156,326,835 | -45.19% | |
| D. E. Shaw & Co., Inc. | 0.21% | 1,104,109 | $332,369,932 | $182,177,985 | -$150,191,947 | -45.19% | |
| Morgan Stanley | 0.02% | 1,032,150 | $310,709,115 | $170,304,750 | -$140,404,365 | -45.19% | |
| Bank Of America Corp | 0.02% | 994,476 | $299,367,191 | $164,088,540 | -$135,278,651 | -45.19% | |
| Legal & General Group Plc | 0.06% | 924,561 | $278,320,594 | $152,552,565 | -$125,768,029 | -45.19% | |
| Manufacturers Life Insurance Company, The | 0.21% | 893,795 | $269,059,154 | $147,476,175 | -$121,582,979 | -45.19% | |
| Northern Trust Corp | 0.03% | 886,900 | $266,983,506 | $146,338,500 | -$120,645,006 | -45.19% | |
| Royal Bank Of Canada | 0.04% | 875,859 | $263,661,000 | $144,516,735 | -$119,144,265 | -45.19% | |
| Vanguard Fiduciary Trust Co | 0.06% | 862,782 | $259,723,265 | $142,359,030 | -$117,364,235 | -45.19% | |
| Deep Track Capital, Lp | 3.66% | 825,000 | $248,349,750 | $136,125,000 | -$112,224,750 | -45.19% | |
| Deutsche Bank Ag\ | 0.07% | 815,400 | $245,459,862 | $134,541,000 | -$110,918,862 | -45.19% | |
| Qube Research & Technologies Ltd | 0.27% | 798,715 | $240,437,176 | $131,787,975 | -$108,649,201 | -45.19% | |
| Charles Schwab Investment Management Inc | 0.03% | 755,377 | $227,391,139 | $124,637,205 | -$102,753,934 | -45.19% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.05% | 677,519 | $224,170,712 | $111,790,635 | -$112,380,077 | -50.13% | |
| Los Angeles Capital Management Llc | 0.81% | 729,635 | $219,642,021 | $120,389,775 | -$99,252,246 | -45.19% | |
| Aqr Capital Management Llc | 0.08% | 728,039 | $218,994,064 | $120,126,435 | -$98,867,629 | -45.15% | |
| Federated Hermes, Inc. | 0.31% | 719,905 | $216,713,003 | $118,784,325 | -$97,928,678 | -45.19% | |
| Ubs Group Ag | 0.03% | 627,004 | $188,747,013 | $103,455,660 | -$85,291,353 | -45.19% | |
| Loomis Sayles & Co L P | 0.22% | 580,187 | $174,653,692 | $95,730,855 | -$78,922,837 | -45.19% | |
| Goldman Sachs Group Inc | 0.02% | 574,757 | $173,019,032 | $94,834,905 | -$78,184,127 | -45.19% | |
| Bank Of New York Mellon Corp | 0.02% | 492,071 | $148,128,276 | $81,191,715 | -$66,936,561 | -45.19% | |
| Polar Capital Holdings Plc | 0.41% | 482,751 | $145,322,534 | $79,653,915 | -$65,668,619 | -45.19% | |
| Paradigm Biocapital Advisors Lp | 2.71% | 480,000 | $144,494,400 | $79,200,000 | -$65,294,400 | -45.19% | |
| First Trust Advisors Lp | 0.07% | 421,534 | $126,894,361 | $69,553,110 | -$57,341,251 | -45.19% | |
| Raymond James Financial Inc | 0.03% | 392,799 | $118,244,275 | $64,811,835 | -$53,432,440 | -45.19% | |
| Dimensional Fund Advisors Lp | 0.02% | 392,022 | $117,970,419 | $64,683,630 | -$53,286,789 | -45.17% | |
| Swiss National Bank | 0.06% | 374,080 | $112,609,302 | $61,723,200 | -$50,886,102 | -45.19% | |
| Massachusetts Financial Services Co | 0.03% | 350,560 | $105,524,729 | $57,842,400 | -$47,682,329 | -45.19% | |
| Canada Pension Plan Investment Board | 0.06% | 334,246 | $100,618,073 | $55,150,590 | -$45,467,483 | -45.19% | |
| Millennium Management Llc | 0.06% | 316,001 | $95,125,781 | $52,140,165 | -$42,985,616 | -45.19% |
Frequently asked questions about ALNY
Who are the largest institutional holders of ALNY?
The largest institutional holders of ALNY reported in the latest SEC Form 13F filings include Fmr Llc, Capital World Investors, Blackrock, Inc., Capital Research Global Investors, and Banque Cantonale Vaudoise. InsiderSet ranks institutional holders by their latest reported ALNY position.
What is ALNY institutional ownership?
This page tracks ALNY positions reported by institutional investment managers through SEC Form 13F. ALNYLAM PHARMACEUTICALS INC (ALNY) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own ALNY?
InsiderSet currently tracks 759 institutional managers reporting ALNY holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of ALNY shareholders.
How much ALNY stock do institutions own?
Institutional investment managers disclosed approximately $41.69B in ALNY holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was ALNY institutional ownership last updated?
The latest ALNY institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional ALNY holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its ALNY position after the reporting date.
Are institutions buying or selling ALNY?
Institutional buying and selling can be analyzed by comparing ALNY positions across consecutive 13F reporting periods. InsiderSet's ALNY Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View ALNY ownership changes.
How has ALNY institutional ownership changed over time?
InsiderSet tracks ALNY institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.