APELLIS PHARMACEUTICALS INC (APLS) Top Institutional Shareholders
APELLIS PHARMACEUTICALS INC (APLS) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $5.43B in APLS holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of APLS tracked by InsiderSet, reporting ownership valued at approximately $544.59M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $555.42M, representing an estimated gain of +1.99% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 54% of the total disclosed APLS value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Avoro Capital Advisors Llc, Morgan Stanley, and several other long-term asset managers with concentrated positions in APELLIS PHARMACEUTICALS INC (APLS).
This page ranks the largest institutional APLS shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
315
Total Reported Value
$5.43B
Largest Holder
Blackrock, Inc.
Largest Position
$544.59M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
137
Funds Exiting Positions
1
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.01% | 13,536,964 | $544,592,062 | $555,421,633 | +$10,829,571 | +1.99% | |
| Avoro Capital Advisors Llc | 4.84% | 12,222,222 | $491,699,991 | $501,477,769 | +$9,777,778 | +1.99% | |
| Morgan Stanley | 0.02% | 10,042,399 | $404,005,720 | $412,039,631 | +$8,033,911 | +1.99% | |
| State Street Corp | 0.01% | 6,844,990 | $275,373,948 | $280,849,940 | +$5,475,992 | +1.99% | |
| Ubs Group Ag | 0.04% | 6,206,681 | $249,694,778 | $254,660,121 | +$4,965,343 | +1.99% | |
| Vanguard Portfolio Management Llc | 0.01% | 5,404,559 | $217,425,409 | $221,749,056 | +$4,323,647 | +1.99% | |
| Pentwater Capital Management Lp | 1.50% | 5,250,000 | $211,207,500 | $215,407,500 | +$4,200,000 | +1.99% | |
| Vanguard Capital Management Llc | 0.00% | 4,768,944 | $191,854,617 | $195,669,772 | +$3,815,155 | +1.99% | |
| Deep Track Capital, Lp | 3.76% | 4,532,374 | $182,337,406 | $185,963,305 | +$3,625,899 | +1.99% | |
| Point72 Asset Management, L.P. | 0.29% | 4,183,918 | $168,319,021 | $171,666,156 | +$3,347,135 | +1.99% | |
| Rtw Investments, Lp | 1.48% | 3,685,045 | $148,249,360 | $151,197,396 | +$2,948,036 | +1.99% | |
| Hbk Investments L P | 1.80% | 3,550,000 | $142,816,500 | $145,656,500 | +$2,840,000 | +1.99% | |
| Suvretta Capital Management, Llc | 3.84% | 3,518,471 | $141,548,088 | $144,362,865 | +$2,814,777 | +1.99% | |
| Millennium Management Llc | 0.07% | 2,256,802 | $90,791,144 | $92,596,586 | +$1,805,442 | +1.99% | |
| Geode Capital Management, Llc | 0.01% | 2,075,075 | $83,502,254 | $85,140,327 | +$1,638,073 | +1.96% | |
| Goldman Sachs Group Inc | 0.01% | 1,980,144 | $79,661,193 | $81,245,308 | +$1,584,115 | +1.99% | |
| Balyasny Asset Management L.P. | 0.15% | 1,917,501 | $77,141,065 | $78,675,066 | +$1,534,001 | +1.99% | |
| Dimensional Fund Advisors Lp | 0.01% | 1,338,995 | $53,745,011 | $54,938,965 | +$1,193,954 | +2.22% | |
| Tig Advisors, Llc | 2.41% | 1,252,986 | $50,407,627 | $51,410,016 | +$1,002,389 | +1.99% | |
| Toronto Dominion Bank | 0.10% | 1,236,436 | $49,741,815 | $50,730,969 | +$989,154 | +1.99% | |
| Healthcare Of Ontario Pension Plan Trust Fund | 0.08% | 1,202,100 | $48,360,483 | $49,322,163 | +$961,680 | +1.99% | |
| Bank Of America Corp | 0.00% | 1,190,864 | $47,908,459 | $48,861,150 | +$952,691 | +1.99% | |
| Hudson Bay Capital Management Lp | 0.30% | 1,190,416 | $47,890,436 | $48,842,768 | +$952,332 | +1.99% | |
| Fil Ltd | 0.04% | 1,140,000 | $45,862,200 | $46,774,200 | +$912,000 | +1.99% | |
| Kryger Capital Llc | 3.13% | 1,100,000 | $44,253,000 | $45,133,000 | +$880,000 | +1.99% | |
| Soros Fund Management Llc | 0.58% | 1,056,000 | $42,482,880 | $43,327,680 | +$844,800 | +1.99% | |
| Capitolis Liquid Global Markets Llc | 0.26% | 1,013,500 | $40,773,105 | $41,583,905 | +$810,800 | +1.99% | |
| Woodline Partners Lp | 0.15% | 976,175 | $39,271,520 | $40,052,460 | +$780,940 | +1.99% | |
| Renaissance Technologies LLC | Jim Simons | 0.06% | 935,958 | $37,653,590 | $38,402,357 | +$748,767 | +1.99% |
| Marshall Wace, Llp | 0.04% | 929,019 | $37,374,434 | $38,117,650 | +$743,216 | +1.99% | |
| Man Group Plc | 0.08% | 915,689 | $36,838,168 | $37,570,720 | +$732,552 | +1.99% | |
| First Trust Advisors Lp | 0.03% | 903,637 | $36,353,247 | $37,076,226 | +$722,979 | +1.99% | |
| Magnetar Financial Llc | 0.36% | 869,229 | $34,969,082 | $35,664,466 | +$695,384 | +1.99% | |
| Alpine Associates Management Inc. | 2.05% | 864,000 | $34,758,721 | $35,449,920 | +$691,199 | +1.99% | |
| Kynam Capital Management, Lp | 2.11% | 825,000 | $33,189,750 | $33,849,750 | +$660,000 | +1.99% | |
| Oddo Bhf Asset Management Sas | 1.31% | 825,000 | $33,189,750 | $33,849,750 | +$660,000 | +1.99% | |
| Northern Trust Corp | 0.00% | 738,440 | $29,707,442 | $30,298,193 | +$590,751 | +1.99% | |
| Weiss Asset Management Lp | 0.52% | 700,000 | $28,161,000 | $28,721,000 | +$560,000 | +1.99% | |
| Charles Schwab Investment Management Inc | 0.00% | 675,864 | $27,190,009 | $27,730,700 | +$540,691 | +1.99% | |
| Citigroup Inc | 0.02% | 657,223 | $26,440,081 | $26,965,860 | +$525,779 | +1.99% | |
| Vanguard Fiduciary Trust Co | 0.01% | 654,922 | $26,347,512 | $26,871,450 | +$523,938 | +1.99% | |
| Tudor Investment Corp Et Al | 0.14% | 650,000 | $26,149,500 | $26,669,500 | +$520,000 | +1.99% | |
| Bnp Paribas Financial Markets | 0.02% | 584,192 | $23,502,044 | $23,969,398 | +$467,354 | +1.99% | |
| Ossiam | 0.39% | 555,953 | $22,365,989 | $22,810,752 | +$444,763 | +1.99% | |
| Bank Of New York Mellon Corp | 0.00% | 524,789 | $21,112,247 | $21,532,093 | +$419,846 | +1.99% | |
| Two Sigma Investments, Lp | 0.02% | 521,965 | $20,998,652 | $21,416,224 | +$417,572 | +1.99% | |
| Principal Financial Group Inc | 0.01% | 499,053 | $20,076,903 | $20,476,145 | +$399,242 | +1.99% | |
| Absolute Gestao De Investimentos Ltda. | 2.07% | 450,000 | $18,103,500 | $18,463,500 | +$360,000 | +1.99% | |
| Squarepoint Ops Llc | 0.04% | 449,796 | $18,095,293 | $18,455,130 | +$359,837 | +1.99% | |
| Invesco Ltd. | 0.00% | 437,868 | $17,615,430 | $17,965,724 | +$350,294 | +1.99% |
Frequently asked questions about APLS
Who owns the most APLS stock?
The largest holders of APLS are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for APELLIS PHARMACEUTICALS INC (APLS).
Is APLS widely held by superinvestors?
Many widely followed stocks like APLS appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly APLS is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.