BCYC Institutional Ownership & Shareholders
BICYCLE THERAPEUTICS PLC-ADR (BCYC) is currently held by 98 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $156.75M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of BCYC tracked by InsiderSet, reporting ownership valued at approximately $46.15M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $39.84M, representing an estimated loss of -13.68% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 77% of the total disclosed BCYC value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Fcpm Iii Services B.V., Armistice Capital, Llc, and several other long-term asset managers with concentrated positions in BICYCLE THERAPEUTICS PLC-ADR (BCYC).
This page ranks the largest institutional BCYC shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
98
Total Reported Value
$156.75M
Largest Holder
Baker Bros. Advisors Lp
Largest Position
$46.15M
Insider Transactions (90d)
12
Latest Filing Quarter
Q2 2026
New Institutional Positions
138
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors Lp | 0.23% | 10,885,357 | $46,153,914 | $39,840,407 | -$6,313,507 | -13.68% | |
| Fcpm Iii Services B.V. | 1.96% | 3,468,430 | $14,706,143 | $12,694,454 | -$2,011,689 | -13.68% | |
| Armistice Capital, Llc | 0.40% | 3,398,000 | $14,407,520 | $12,436,680 | -$1,970,840 | -13.68% | |
| Long Focus Capital Management, Llc | 0.57% | 3,310,687 | $14,037,313 | $12,117,114 | -$1,920,199 | -13.68% | |
| Acadian Asset Management Llc | 0.01% | 1,968,025 | $8,319,000 | $7,202,972 | -$1,116,029 | -13.42% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 1,533,400 | $6,501,616 | $5,612,244 | -$889,372 | -13.68% |
| Gsk Plc | 1.08% | 1,529,561 | $6,485,339 | $5,598,193 | -$887,146 | -13.68% | |
| Price T Rowe Associates Inc | 0.00% | 902,150 | $3,826,000 | $3,301,869 | -$524,131 | -13.70% | |
| Marshall Wace, Llp | 0.00% | 797,940 | $3,383,266 | $2,920,460 | -$462,806 | -13.68% | |
| Qube Research & Technologies Ltd | 0.00% | 775,567 | $3,288,404 | $2,838,575 | -$449,829 | -13.68% | |
| Morgan Stanley | 0.00% | 667,269 | $2,829,221 | $2,442,205 | -$387,016 | -13.68% | |
| Schroder Investment Management Group | 0.00% | 615,833 | $2,555,707 | $2,253,949 | -$301,758 | -11.81% | |
| Citadel Advisors Llc | 0.00% | 554,225 | $2,349,914 | $2,028,464 | -$321,451 | -13.68% | |
| Millennium Management Llc | 0.00% | 553,967 | $2,348,820 | $2,027,519 | -$321,301 | -13.68% | |
| Diadema Partners Lp | 0.69% | 462,724 | $1,961,950 | $1,693,570 | -$268,380 | -13.68% | |
| Peapod Lane Capital Llc | 1.38% | 501,708 | $1,846,285 | $1,836,251 | -$10,034 | -0.54% | |
| Two Sigma Investments, Lp | 0.00% | 434,577 | $1,842,606 | $1,590,552 | -$252,054 | -13.68% | |
| Jane Street Group, Llc | 0.00% | 392,163 | $1,662,771 | $1,435,317 | -$227,454 | -13.68% | |
| Birchview Capital, Lp | 0.62% | 313,616 | $1,329,732 | $1,147,835 | -$181,897 | -13.68% | |
| Blackrock, Inc. | 0.00% | 280,386 | $1,188,837 | $1,026,213 | -$162,624 | -13.68% | |
| Moore Capital Management, Lp | 0.03% | 275,000 | $1,166,000 | $1,006,500 | -$159,500 | -13.68% | |
| Rangeley Capital, Llc | 1.00% | 253,500 | $1,074,840 | $927,810 | -$147,030 | -13.68% | |
| Palo Alto Investors Lp | 0.12% | 201,890 | $856,014 | $738,917 | -$117,097 | -13.68% | |
| Sculptor Capital Lp | 0.01% | 197,904 | $839,113 | $724,329 | -$114,784 | -13.68% | |
| Eversept Partners, Lp | 0.04% | 190,715 | $808,632 | $698,017 | -$110,615 | -13.68% | |
| Flax Pond Capital, Llc | 0.53% | 180,086 | $763,565 | $659,115 | -$104,450 | -13.68% | |
| Jump Financial, Llc | 0.01% | 167,100 | $708,504 | $611,586 | -$96,918 | -13.68% | |
| Point72 Asset Management, L.P. | 0.00% | 149,936 | $635,729 | $548,766 | -$86,963 | -13.68% | |
| Pinnacle Associates Ltd | 0.01% | 160,551 | $590,828 | $587,617 | -$3,211 | -0.54% | |
| Manufacturers Life Insurance Company, The | 0.00% | 127,863 | $542,139 | $467,979 | -$74,160 | -13.68% | |
| Goldman Sachs Group Inc | 0.00% | 121,281 | $514,231 | $443,888 | -$70,343 | -13.68% | |
| Persistent Asset Partners Ltd | 0.16% | 117,254 | $497,157 | $429,150 | -$68,007 | -13.68% | |
| Xtx Topco Ltd | 0.01% | 109,801 | $465,556 | $401,872 | -$63,684 | -13.68% | |
| Quadrature Capital Ltd | 0.00% | 104,092 | $441,350 | $380,977 | -$60,373 | -13.68% | |
| Td Asset Management Inc | 0.00% | 91,992 | $390,046 | $336,691 | -$53,355 | -13.68% | |
| Virtus Investment Advisers, Llc | 0.08% | 80,789 | $342,545 | $295,688 | -$46,857 | -13.68% | |
| Nano Cap New Millennium Growth Fund L P | 0.26% | 80,000 | $339,200 | $292,800 | -$46,400 | -13.68% | |
| Entrypoint Capital, Llc | 0.08% | 77,743 | $329,630 | $284,539 | -$45,091 | -13.68% | |
| Hrt Financial Lp | 0.00% | 66,237 | $280,000 | $242,427 | -$37,573 | -13.42% | |
| Dafna Capital Management Llc | 0.05% | 64,492 | $273,446 | $236,041 | -$37,405 | -13.68% | |
| State Of Tennessee, Department Of Treasury | 0.00% | 61,153 | $259,289 | $223,820 | -$35,469 | -13.68% | |
| Sei Investments Co | 0.00% | 52,784 | $223,804 | $193,189 | -$30,615 | -13.68% | |
| Alps Advisors Inc | 0.00% | 51,122 | $216,757 | $187,107 | -$29,650 | -13.68% | |
| Verdad Advisers, Lp | 0.21% | 51,100 | $216,664 | $187,026 | -$29,638 | -13.68% | |
| Adar1 Capital Management, Llc | 0.01% | 50,638 | $214,705 | $185,335 | -$29,370 | -13.68% | |
| Simplex Trading, Llc | 0.00% | 35,232 | $149,383 | $128,949 | -$20,434 | -13.68% | |
| Susquehanna International Group, Llp | 0.00% | 31,957 | $135,498 | $116,963 | -$18,535 | -13.68% | |
| Trexquant Investment Lp | 0.00% | 31,044 | $131,627 | $113,621 | -$18,006 | -13.68% | |
| Gsa Capital Partners Llp | 0.01% | 30,785 | $131,000 | $112,673 | -$18,327 | -13.99% | |
| State Street Corp | 0.00% | 30,829 | $130,715 | $112,834 | -$17,881 | -13.68% |
Frequently asked questions about BCYC
Who are the largest institutional holders of BCYC?
The largest institutional holders of BCYC reported in the latest SEC Form 13F filings include Baker Bros. Advisors Lp, Fcpm Iii Services B.V., Armistice Capital, Llc, Long Focus Capital Management, Llc, and Acadian Asset Management Llc. InsiderSet ranks institutional holders by their latest reported BCYC position.
What is BCYC institutional ownership?
This page tracks BCYC positions reported by institutional investment managers through SEC Form 13F. BICYCLE THERAPEUTICS PLC-ADR (BCYC) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own BCYC?
InsiderSet currently tracks 98 institutional managers reporting BCYC holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of BCYC shareholders.
How much BCYC stock do institutions own?
Institutional investment managers disclosed approximately $156.75M in BCYC holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was BCYC institutional ownership last updated?
The latest BCYC institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional BCYC holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its BCYC position after the reporting date.
Are institutions buying or selling BCYC?
Institutional buying and selling can be analyzed by comparing BCYC positions across consecutive 13F reporting periods. InsiderSet's BCYC Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View BCYC ownership changes.
How has BCYC institutional ownership changed over time?
InsiderSet tracks BCYC institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.