BICYCLE THERAPEUTICS PLC-ADR (BCYC) Institutional Shareholders

BICYCLE THERAPEUTICS PLC-ADR (BCYC) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $161.34M in BCYC holdings during the latest filing period.

Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of BCYC tracked by InsiderSet, reporting ownership valued at approximately $50.51M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $42.02M, representing an estimated loss of -16.81% since the filing period.

The top 10 institutional shareholders tracked on this page collectively account for approximately 79% of the total disclosed BCYC value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Fcpm Iii Services B.V., Armistice Capital, Llc, and several other long-term asset managers with concentrated positions in BICYCLE THERAPEUTICS PLC-ADR (BCYC).

This page ranks the largest institutional BCYC shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.

Institutional Holders

98

Total Reported Value

$161.34M

Largest Holder

Baker Bros. Advisors Lp

Largest Position

$50.51M

Insider Transactions (90d)

11

Latest Filing Quarter

Q2 2026

New Institutional Positions

126

Funds Exiting Positions

0

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NameInvestor/ManagerPortfolio %QuantityReported BalanceCurrent Estimated ValueGain/loss Since FilingEstimated Portfolio Performance
Baker Bros. Advisors Lp0.29%10,885,357$50,508,056$42,017,478-$8,490,578-16.81%
Fcpm Iii Services B.V.2.23%3,468,430$16,093,515$13,388,140-$2,705,375-16.81%
Armistice Capital, Llc0.52%3,398,000$15,766,720$13,116,280-$2,650,440-16.81%
Long Focus Capital Management, Llc0.67%3,310,687$15,361,588$12,779,252-$2,582,336-16.81%
Siren, L.L.C.0.20%1,560,882$7,242,492$6,025,005-$1,217,487-16.81%
Gsk Plc1.18%1,529,561$7,097,163$5,904,105-$1,193,058-16.81%
Principal Financial Group Inc0.00%1,174,625$5,450,260$4,534,053-$916,208-16.81%
Renaissance Technologies LLCJim Simons0.01%979,300$4,543,952$3,780,098-$763,854-16.81%
Morgan Stanley0.00%618,327$2,869,038$2,386,742-$482,296-16.81%
Schroder Investment Management Group0.00%615,833$2,672,715$2,377,115-$295,600-11.06%
Peapod Lane Capital Llc1.54%537,978$2,281,027$2,076,595-$204,432-8.96%
Diadema Partners Lp0.91%476,424$2,210,607$1,838,997-$371,610-16.81%
Birchview Capital, Lp1.22%463,599$2,151,099$1,789,492-$361,607-16.81%
Silvercrest Asset Management Group Llc0.01%428,684$1,989,094$1,654,720-$334,374-16.81%
Marshall Wace, Llp0.00%377,335$1,750,834$1,456,513-$294,321-16.81%
Citadel Advisors Llc0.00%377,085$1,749,674$1,455,548-$294,126-16.81%
Qube Research & Technologies Ltd0.00%308,617$1,431,983$1,191,262-$240,721-16.81%
Millennium Management Llc0.00%283,986$1,317,695$1,096,186-$221,509-16.81%
Blackrock, Inc.0.00%278,992$1,294,523$1,076,909-$217,614-16.81%
Moore Capital Management, Lp0.05%275,000$1,276,000$1,061,500-$214,500-16.81%
Rangeley Capital, Llc1.16%232,260$1,077,686$896,524-$181,162-16.81%
Jane Street Group, Llc0.00%218,115$1,012,053$841,924-$170,129-16.81%
Palo Alto Investors Lp0.14%201,890$936,770$779,295-$157,475-16.81%
Eversept Partners, Lp0.06%190,715$884,918$736,160-$148,758-16.81%
Platinum Investment Management Ltd0.22%184,603$856,558$712,568-$143,990-16.81%
Flax Pond Capital, Llc0.66%176,136$817,271$679,885-$137,386-16.81%
Pinnacle Associates Ltd0.01%189,990$805,558$733,361-$72,197-8.96%
Two Sigma Investments, Lp0.00%164,800$764,672$636,128-$128,544-16.81%
Point72 Asset Management, L.P.0.00%130,422$605,158$503,429-$101,729-16.81%
Manufacturers Life Insurance Company, The0.00%127,863$593,284$493,551-$99,733-16.81%
Persistent Asset Partners Ltd0.22%120,437$558,828$464,887-$93,941-16.81%
Marex Group Plc0.01%115,000$533,600$443,900-$89,700-16.81%
Goldman Sachs Group Inc0.00%110,147$511,082$425,167-$85,915-16.81%
Xtx Topco Ltd0.01%106,392$493,659$410,673-$82,986-16.81%
Td Asset Management Inc0.00%91,992$426,843$355,089-$71,754-16.81%
Adar1 Capital Management, Llc0.02%71,298$330,823$275,210-$55,613-16.81%
Marquette Asset Management, Llc0.04%72,854$308,901$281,216-$27,685-8.96%
Dafna Capital Management Llc0.07%64,492$299,243$248,939-$50,304-16.81%
Entrypoint Capital, Llc0.09%63,906$296,524$246,677-$49,847-16.81%
Man Group Plc0.00%63,305$293,735$244,357-$49,378-16.81%
Axq Capital, Lp0.04%63,134$292,942$243,697-$49,245-16.81%
State Of Tennessee, Department Of Treasury0.00%61,153$283,750$236,051-$47,699-16.81%
Sei Investments Co0.00%52,784$244,918$203,746-$41,172-16.81%
Jump Financial, Llc0.00%52,544$243,804$202,820-$40,984-16.81%
Alps Advisors Inc0.00%51,122$216,757$197,331-$19,426-8.96%
Susquehanna International Group, Llp0.00%37,888$175,800$146,248-$29,552-16.81%
Virtus Investment Advisers, Llc0.05%36,601$169,829$141,280-$28,549-16.81%
Engineers Gate Manager Lp0.00%35,400$164,256$136,644-$27,612-16.81%
Ubs Group Ag0.00%32,159$149,218$124,134-$25,084-16.81%
State Street Corp0.00%30,512$141,576$117,776-$23,800-16.81%

Frequently asked questions about BCYC

  • Who owns the most BCYC stock?

    The largest holders of BCYC are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for BICYCLE THERAPEUTICS PLC-ADR (BCYC).

  • Is BCYC widely held by superinvestors?

    Many widely followed stocks like BCYC appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly BCYC is represented among the institutional managers we track.

  • What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?

    Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.