DNLI Institutional Ownership & Shareholders
DENALI THERAPEUTICS INC (DNLI) is currently held by 286 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $4.40B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Banque Cantonale Vaudoise is currently the largest disclosed institutional shareholder of DNLI tracked by InsiderSet, reporting ownership valued at approximately $461.00M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $339,518.44, representing an estimated loss of -99.93% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 55% of the total disclosed DNLI value among the investors covered in this analysis. Major shareholders include Banque Cantonale Vaudoise, T. Rowe Price Investment Management, Inc., Blackrock, Inc., and several other long-term asset managers with concentrated positions in DENALI THERAPEUTICS INC (DNLI).
This page ranks the largest institutional DNLI shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
286
Total Reported Value
$4.40B
Largest Holder
Banque Cantonale Vaudoise
Largest Position
$461.00M
Insider Transactions (90d)
6
Latest Filing Quarter
Q2 2026
New Institutional Positions
57
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Banque Cantonale Vaudoise | 0.06% | 17,926 | $461,000,000 | $339,518 | -$460,660,482 | -99.93% | |
| T. Rowe Price Investment Management, Inc. | 0.27% | 16,178,963 | $416,123,000 | $306,429,559 | -$109,693,441 | -26.36% | |
| Blackrock, Inc. | 0.01% | 14,026,094 | $360,751,137 | $265,654,220 | -$95,096,917 | -26.36% | |
| Baillie Gifford & Co | 0.28% | 11,960,230 | $307,617,116 | $226,526,756 | -$81,090,360 | -26.36% | |
| State Street Corp | 0.01% | 7,049,304 | $181,308,099 | $133,513,818 | -$47,794,281 | -26.36% | |
| Vanguard Portfolio Management Llc | 0.01% | 6,477,057 | $166,589,906 | $122,675,460 | -$43,914,446 | -26.36% | |
| Vanguard Capital Management Llc | 0.00% | 6,275,729 | $161,411,750 | $118,862,307 | -$42,549,443 | -26.36% | |
| Temasek Holdings (Private) Ltd | 0.40% | 7,012,974 | $144,958,173 | $132,825,728 | -$12,132,445 | -8.37% | |
| Fmr Llc | 0.01% | 4,535,836 | $116,661,699 | $85,908,734 | -$30,752,965 | -26.36% | |
| Goldman Sachs Group Inc | 0.01% | 4,155,895 | $106,889,625 | $78,712,651 | -$28,176,974 | -26.36% | |
| Geode Capital Management, Llc | 0.01% | 3,973,342 | $102,212,911 | $75,255,097 | -$26,957,814 | -26.37% | |
| Holocene Advisors, Lp | 0.23% | 3,905,225 | $100,442,387 | $73,964,962 | -$26,477,426 | -26.36% | |
| Baker Bros. Advisors Lp | 0.48% | 3,734,336 | $96,047,122 | $70,728,324 | -$25,318,798 | -26.36% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.02% | 4,432,314 | $85,100,430 | $83,948,027 | -$1,152,403 | -1.35% | |
| Price T Rowe Associates Inc | 0.01% | 3,136,149 | $80,663,000 | $59,398,662 | -$21,264,338 | -26.36% | |
| Ubs Group Ag | 0.01% | 3,120,592 | $80,261,627 | $59,104,012 | -$21,157,615 | -26.36% | |
| Dimensional Fund Advisors Lp | 0.01% | 2,860,604 | $73,575,277 | $54,179,840 | -$19,395,437 | -26.36% | |
| Norges Bank | 0.01% | 2,824,746 | $72,652,467 | $53,500,689 | -$19,151,778 | -26.36% | |
| Pictet Asset Management Holding Sa | 0.07% | 2,791,206 | $71,894,854 | $52,865,442 | -$19,029,412 | -26.47% | |
| Capital Research Global Investors | 0.01% | 2,565,817 | $65,992,813 | $48,596,574 | -$17,396,239 | -26.36% | |
| Fisher Asset Management, Llc | 0.02% | 2,414,162 | $62,092,245 | $45,724,228 | -$16,368,017 | -26.36% | |
| Alliancebernstein L.P. | 0.02% | 2,984,807 | $57,308,294 | $56,532,245 | -$776,049 | -1.35% | |
| Nomura Asset Management International Inc. | 0.09% | 2,208,263 | $56,797,000 | $41,824,501 | -$14,972,499 | -26.36% | |
| Casdin Capital, Llc | 2.63% | 2,045,000 | $52,597,400 | $38,732,300 | -$13,865,100 | -26.36% | |
| Crestline Management, L.P. | 91.90% | 1,910,732 | $49,144,027 | $36,189,264 | -$12,954,763 | -26.36% | |
| Principal Financial Group Inc | 0.02% | 1,420,083 | $36,524,535 | $26,896,372 | -$9,628,163 | -26.36% | |
| Foresite Capital Management Vi Llc | 5.59% | 1,396,771 | $35,924,950 | $26,454,843 | -$9,470,107 | -26.36% | |
| Siren, L.L.C. | 0.73% | 1,396,513 | $35,918,314 | $26,449,956 | -$9,468,358 | -26.36% | |
| Northern Trust Corp | 0.00% | 1,389,765 | $35,744,756 | $26,322,149 | -$9,422,607 | -26.36% | |
| Bnp Paribas Asset Management Holding S.A. | 0.03% | 1,355,514 | $34,863,820 | $25,673,435 | -$9,190,385 | -26.36% | |
| Aberdeen Group Plc | 0.05% | 1,345,481 | $34,605,771 | $25,483,410 | -$9,122,361 | -26.36% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,244,955 | $32,020,243 | $23,579,448 | -$8,440,795 | -26.36% | |
| Bank Of America Corp | 0.00% | 1,230,957 | $31,660,215 | $23,314,326 | -$8,345,889 | -26.36% | |
| Artisan Partners Limited Partnership | 0.05% | 1,224,497 | $31,494,063 | $23,191,973 | -$8,302,090 | -26.36% | |
| Candriam S.C.A. | 0.14% | 1,189,886 | $30,574,423 | $22,536,441 | -$8,037,982 | -26.29% | |
| Millennium Management Llc | 0.02% | 1,125,748 | $28,954,239 | $21,321,667 | -$7,632,572 | -26.36% | |
| Adar1 Capital Management, Llc | 1.24% | 1,029,080 | $26,467,938 | $19,490,775 | -$6,977,163 | -26.36% | |
| Vanguard Fiduciary Trust Co | 0.01% | 991,904 | $25,511,771 | $18,786,662 | -$6,725,109 | -26.36% | |
| Morgan Stanley | 0.00% | 961,050 | $24,718,235 | $18,202,287 | -$6,515,948 | -26.36% | |
| Bank Of New York Mellon Corp | 0.00% | 800,283 | $20,583,293 | $15,157,360 | -$5,425,933 | -26.36% | |
| Dafna Capital Management Llc | 3.62% | 739,014 | $19,007,440 | $13,996,925 | -$5,010,515 | -26.36% | |
| American Century Companies Inc | 0.01% | 712,526 | $18,326,346 | $13,495,242 | -$4,831,104 | -26.36% | |
| Cercano Management Llc | 2.14% | 625,000 | $16,075,000 | $11,837,500 | -$4,237,500 | -26.36% | |
| Nuveen, Llc | 0.00% | 608,967 | $15,662,631 | $11,533,835 | -$4,128,796 | -26.36% | |
| Marshall Wace, Llp | 0.01% | 549,830 | $14,141,627 | $10,413,780 | -$3,727,847 | -26.36% | |
| Segall Bryant & Hamill, Llc | 0.16% | 519,483 | $13,361,103 | $9,839,008 | -$3,522,095 | -26.36% | |
| Citigroup Inc | 0.01% | 487,278 | $12,532,790 | $9,229,045 | -$3,303,745 | -26.36% | |
| Defilade Capital Management, L.P. | 1.35% | 391,866 | $10,078,794 | $7,421,942 | -$2,656,852 | -26.36% | |
| Aqr Capital Management Llc | 0.00% | 388,469 | $9,991,416 | $7,357,603 | -$2,633,813 | -26.36% | |
| Ensign Peak Advisors, Inc | 0.02% | 515,721 | $9,901,843 | $9,767,756 | -$134,087 | -1.35% |
Frequently asked questions about DNLI
Who are the largest institutional holders of DNLI?
The largest institutional holders of DNLI reported in the latest SEC Form 13F filings include Banque Cantonale Vaudoise, T. Rowe Price Investment Management, Inc., Blackrock, Inc., Baillie Gifford & Co, and State Street Corp. InsiderSet ranks institutional holders by their latest reported DNLI position.
What is DNLI institutional ownership?
This page tracks DNLI positions reported by institutional investment managers through SEC Form 13F. DENALI THERAPEUTICS INC (DNLI) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own DNLI?
InsiderSet currently tracks 286 institutional managers reporting DNLI holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of DNLI shareholders.
How much DNLI stock do institutions own?
Institutional investment managers disclosed approximately $4.40B in DNLI holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was DNLI institutional ownership last updated?
The latest DNLI institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional DNLI holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its DNLI position after the reporting date.
Are institutions buying or selling DNLI?
Institutional buying and selling can be analyzed by comparing DNLI positions across consecutive 13F reporting periods. InsiderSet's DNLI Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View DNLI ownership changes.
How has DNLI institutional ownership changed over time?
InsiderSet tracks DNLI institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.