ESPERION THERAPEUTICS INC (ESPR) Top Institutional Shareholders
ESPERION THERAPEUTICS INC (ESPR) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $473.05M in ESPR holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of ESPR tracked by InsiderSet, reporting ownership valued at approximately $48.92M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $56.59M, representing an estimated gain of +15.69% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 59% of the total disclosed ESPR value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Wasatch Advisors Lp, Two Seas Capital Lp, and several other long-term asset managers with concentrated positions in ESPERION THERAPEUTICS INC (ESPR).
This page ranks the largest institutional ESPR shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
202
Total Reported Value
$473.05M
Largest Holder
Blackrock, Inc.
Largest Position
$48.92M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
174
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 17,852,427 | $48,915,650 | $56,592,194 | +$7,676,544 | +15.69% | |
| Wasatch Advisors Lp | 0.29% | 15,768,897 | $43,206,778 | $49,987,403 | +$6,780,625 | +15.69% | |
| Two Seas Capital Lp | 1.44% | 11,394,833 | $31,221,842 | $36,121,621 | +$4,899,779 | +15.69% | |
| Orbimed Advisors Llc | 0.63% | 10,570,300 | $28,962,622 | $33,507,851 | +$4,545,229 | +15.69% | |
| Vanguard Capital Management Llc | 0.00% | 10,433,760 | $28,588,502 | $33,075,019 | +$4,486,517 | +15.69% | |
| Two Sigma Investments, Lp | 0.02% | 9,458,779 | $25,917,054 | $29,984,329 | +$4,067,275 | +15.69% | |
| Marshall Wace, Llp | 0.02% | 7,075,083 | $19,385,727 | $22,428,013 | +$3,042,286 | +15.69% | |
| State Street Corp | 0.00% | 7,055,794 | $19,332,876 | $22,366,867 | +$3,033,991 | +15.69% | |
| D. E. Shaw & Co., Inc. | 0.01% | 6,540,785 | $17,921,751 | $20,734,288 | +$2,812,537 | +15.69% | |
| Geode Capital Management, Llc | 0.00% | 5,955,739 | $16,322,581 | $18,879,693 | +$2,557,112 | +15.67% | |
| Aigh Capital Management Llc | 2.47% | 4,400,000 | $12,056,000 | $13,948,000 | +$1,892,000 | +15.69% | |
| Ubs Group Ag | 0.00% | 4,291,711 | $11,759,289 | $13,604,724 | +$1,845,435 | +15.69% | |
| Armistice Capital, Llc | 0.36% | 3,930,125 | $10,768,543 | $12,458,496 | +$1,689,953 | +15.69% | |
| Penderfund Capital Management Ltd. | 1.67% | 3,891,926 | $10,663,877 | $12,337,405 | +$1,673,528 | +15.69% | |
| Nuveen, Llc | 0.00% | 3,613,709 | $9,901,563 | $11,455,458 | +$1,553,895 | +15.69% | |
| Vanguard Portfolio Management Llc | 0.00% | 3,532,563 | $9,679,223 | $11,198,225 | +$1,519,002 | +15.69% | |
| Privium Fund Management B.V. | 1.88% | 3,299,441 | $9,040,468 | $10,459,228 | +$1,418,760 | +15.69% | |
| Morgan Stanley | 0.00% | 2,735,644 | $7,495,664 | $8,671,991 | +$1,176,327 | +15.69% | |
| Royce & Associates Lp | 0.07% | 2,626,995 | $7,197,966 | $8,327,574 | +$1,129,608 | +15.69% | |
| Goldman Sachs Group Inc | 0.00% | 2,410,454 | $6,604,644 | $7,641,139 | +$1,036,495 | +15.69% | |
| Jones Financial Companies Lllp | 0.00% | 2,135,741 | $5,851,930 | $6,770,299 | +$918,369 | +15.69% | |
| Northern Trust Corp | 0.00% | 2,104,008 | $5,764,982 | $6,669,705 | +$904,723 | +15.69% | |
| Voleon Capital Management Lp | 0.11% | 1,916,698 | $5,251,753 | $6,075,933 | +$824,180 | +15.69% | |
| Eversept Partners, Lp | 0.31% | 1,735,963 | $4,756,539 | $5,503,003 | +$746,464 | +15.69% | |
| Velan Capital Investment Management Lp | 2.95% | 1,720,000 | $4,712,800 | $5,452,400 | +$739,600 | +15.69% | |
| Point72 Asset Management, L.P. | 0.01% | 1,689,372 | $4,628,879 | $5,355,309 | +$726,430 | +15.69% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 1,620,100 | $4,439,074 | $5,135,717 | +$696,643 | +15.69% |
| Vanguard Fiduciary Trust Co | 0.00% | 1,564,234 | $4,286,001 | $4,958,622 | +$672,621 | +15.69% | |
| Barclays Plc | 0.00% | 1,301,911 | $3,567,237 | $4,127,058 | +$559,821 | +15.69% | |
| Deutsche Bank Ag\ | 0.00% | 1,093,291 | $2,995,617 | $3,465,732 | +$470,115 | +15.69% | |
| Rhenman & Partners Asset Management Ab | 0.33% | 985,000 | $2,698,900 | $3,122,450 | +$423,550 | +15.69% | |
| Susquehanna International Group, Llp | 0.00% | 850,505 | $2,330,384 | $2,696,101 | +$365,717 | +15.69% | |
| Invesco Ltd. | 0.00% | 742,640 | $2,034,834 | $2,354,169 | +$319,335 | +15.69% | |
| Squarepoint Ops Llc | 0.00% | 700,153 | $1,918,419 | $2,219,485 | +$301,066 | +15.69% | |
| Wellington Management Group Llp | 0.00% | 695,848 | $1,906,623 | $2,205,838 | +$299,215 | +15.69% | |
| Jump Financial, Llc | 0.03% | 689,874 | $1,890,254 | $2,186,901 | +$296,647 | +15.69% | |
| Charles Schwab Investment Management Inc | 0.00% | 670,285 | $1,836,581 | $2,124,803 | +$288,222 | +15.69% | |
| Mackenzie Financial Corp | 0.00% | 659,120 | $1,805,989 | $2,089,410 | +$283,421 | +15.69% | |
| Millennium Management Llc | 0.00% | 604,345 | $1,655,905 | $1,915,774 | +$259,869 | +15.69% | |
| Lazard Asset Management Llc | 0.00% | 580,705 | $1,591,132 | $1,840,835 | +$249,703 | +15.69% | |
| Bank Of New York Mellon Corp | 0.00% | 555,177 | $1,521,184 | $1,759,911 | +$238,727 | +15.69% | |
| Public Employees Retirement System Of Ohio | 0.00% | 521,081 | $1,427,762 | $1,651,827 | +$224,065 | +15.69% | |
| Citadel Advisors Llc | 0.00% | 467,610 | $1,281,251 | $1,482,324 | +$201,073 | +15.69% | |
| Principal Financial Group Inc | 0.00% | 422,776 | $1,158,407 | $1,340,200 | +$181,793 | +15.69% | |
| Summit Wealth Group, Llc | 0.25% | 405,369 | $1,110,711 | $1,285,020 | +$174,309 | +15.69% | |
| Burkehill Global Management, Lp | 0.05% | 400,000 | $1,096,000 | $1,268,000 | +$172,000 | +15.69% | |
| Fmr Llc | 0.00% | 374,481 | $1,026,079 | $1,187,105 | +$161,026 | +15.69% | |
| Alliancebernstein L.P. | 0.00% | 261,760 | $968,512 | $829,779 | -$138,733 | -14.32% | |
| Man Group Plc | 0.00% | 339,775 | $930,984 | $1,077,087 | +$146,103 | +15.69% | |
| Aqr Capital Management Llc | 0.00% | 314,866 | $862,733 | $998,125 | +$135,392 | +15.69% |
Frequently asked questions about ESPR
Who owns the most ESPR stock?
The largest holders of ESPR are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ESPERION THERAPEUTICS INC (ESPR).
Is ESPR widely held by superinvestors?
Many widely followed stocks like ESPR appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ESPR is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.