PBYI Institutional Ownership & Shareholders
PUMA BIOTECHNOLOGY INC (PBYI) is currently held by 157 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $315.20M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Acorn Capital Advisors, Llc is currently the largest disclosed institutional shareholder of PBYI tracked by InsiderSet, reporting ownership valued at approximately $33.50M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $42.06M, representing an estimated gain of +25.52% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed PBYI value among the investors covered in this analysis. Major shareholders include Acorn Capital Advisors, Llc, Blackrock, Inc., American Century Companies Inc, and several other long-term asset managers with concentrated positions in PUMA BIOTECHNOLOGY INC (PBYI).
This page ranks the largest institutional PBYI shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
157
Total Reported Value
$315.20M
Largest Holder
Acorn Capital Advisors, Llc
Largest Position
$33.50M
Insider Transactions (90d)
3
Latest Filing Quarter
Q2 2026
New Institutional Positions
71
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Acorn Capital Advisors, Llc | 9.14% | 4,131,299 | $33,504,835 | $42,056,624 | +$8,551,789 | +25.52% | |
| Blackrock, Inc. | 0.00% | 3,804,736 | $30,856,410 | $38,732,212 | +$7,875,802 | +25.52% | |
| American Century Companies Inc | 0.01% | 2,319,996 | $18,815,168 | $23,617,559 | +$4,802,391 | +25.52% | |
| Acadian Asset Management Llc | 0.02% | 2,053,523 | $16,649,000 | $20,904,864 | +$4,255,864 | +25.56% | |
| Renaissance Technologies LLC | Jim Simons | 0.02% | 1,836,213 | $14,891,687 | $18,692,648 | +$3,800,961 | +25.52% |
| Vanguard Capital Management Llc | 0.00% | 1,835,643 | $14,887,065 | $18,686,846 | +$3,799,781 | +25.52% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,825,599 | $14,805,608 | $18,584,598 | +$3,778,990 | +25.52% | |
| Lsv Asset Management | 0.02% | 1,617,981 | $13,122,000 | $16,471,047 | +$3,349,047 | +25.52% | |
| Dimensional Fund Advisors Lp | 0.00% | 1,518,014 | $12,311,629 | $15,453,383 | +$3,141,754 | +25.52% | |
| Geode Capital Management, Llc | 0.00% | 1,339,405 | $10,864,667 | $13,635,143 | +$2,770,476 | +25.50% | |
| O'Shaughnessy Asset Management, Llc | 0.04% | 1,123,783 | $9,113,880 | $11,440,111 | +$2,326,231 | +25.52% | |
| State Street Corp | 0.00% | 952,165 | $7,722,058 | $9,693,040 | +$1,970,982 | +25.52% | |
| Kennedy Capital Management Llc | 0.13% | 873,253 | $7,082,082 | $8,889,716 | +$1,807,634 | +25.52% | |
| Bridgeway Capital Management, Llc | 0.11% | 791,616 | $6,420,006 | $8,058,651 | +$1,638,645 | +25.52% | |
| Ritholtz Wealth Management | 0.09% | 749,798 | $6,080,862 | $7,632,944 | +$1,552,082 | +25.52% | |
| Aqr Capital Management Llc | 0.00% | 725,192 | $5,881,307 | $7,382,455 | +$1,501,148 | +25.52% | |
| Goldman Sachs Group Inc | 0.00% | 669,156 | $5,426,855 | $6,812,008 | +$1,385,153 | +25.52% | |
| Northern Trust Corp | 0.00% | 652,386 | $5,290,851 | $6,641,289 | +$1,350,438 | +25.52% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | 642,946 | $5,214,292 | $6,545,190 | +$1,330,898 | +25.52% | |
| Ubs Group Ag | 0.00% | 636,761 | $5,164,131 | $6,482,227 | +$1,318,096 | +25.52% | |
| Millennium Management Llc | 0.00% | 602,240 | $4,884,166 | $6,130,803 | +$1,246,637 | +25.52% | |
| Arrowstreet Capital, Limited Partnership | 0.00% | 532,450 | $4,318,170 | $5,420,341 | +$1,102,171 | +25.52% | |
| Sei Investments Co | 0.00% | 418,669 | $3,395,406 | $4,262,050 | +$866,644 | +25.52% | |
| Globeflex Capital L P | 0.40% | 382,807 | $3,104,565 | $3,896,975 | +$792,410 | +25.52% | |
| Bank Of New York Mellon Corp | 0.00% | 360,734 | $2,925,553 | $3,672,272 | +$746,719 | +25.52% | |
| D. E. Shaw & Co., Inc. | 0.00% | 316,343 | $2,565,542 | $3,220,372 | +$654,830 | +25.52% | |
| State Board Of Administration Of Florida Retirement System | 0.00% | 309,106 | $2,506,850 | $3,146,699 | +$639,849 | +25.52% | |
| Invesco Ltd. | 0.00% | 301,002 | $2,441,127 | $3,064,200 | +$623,073 | +25.52% | |
| Russell Investments Group, Ltd. | 0.00% | 272,234 | $2,207,818 | $2,771,342 | +$563,524 | +25.52% | |
| Vanguard Fiduciary Trust Co | 0.00% | 269,070 | $2,182,158 | $2,739,133 | +$556,975 | +25.52% | |
| Morgan Stanley | 0.00% | 265,670 | $2,154,584 | $2,704,521 | +$549,937 | +25.52% | |
| Federated Hermes, Inc. | 0.00% | 250,766 | $2,033,712 | $2,552,798 | +$519,086 | +25.52% | |
| Empowered Funds, Llc | 0.01% | 220,316 | $1,786,763 | $2,242,817 | +$456,054 | +25.52% | |
| Panagora Asset Management Inc | 0.01% | 217,545 | $1,764,290 | $2,214,608 | +$450,318 | +25.52% | |
| Prudential Financial Inc | 0.00% | 213,599 | $1,732,288 | $2,174,438 | +$442,150 | +25.52% | |
| Jpmorgan Chase & Co | 0.00% | 211,339 | $1,730,866 | $2,151,431 | +$420,565 | +24.30% | |
| Fmr Llc | 0.00% | 211,444 | $1,714,811 | $2,152,500 | +$437,689 | +25.52% | |
| State Of Wisconsin Investment Board | 0.00% | 188,232 | $1,526,562 | $1,916,202 | +$389,640 | +25.52% | |
| Haven Private, Llc | 0.57% | 146,700 | $1,456,731 | $1,493,406 | +$36,675 | +2.52% | |
| Prospera Financial Services Inc | 0.02% | 158,762 | $1,287,530 | $1,616,197 | +$328,667 | +25.53% | |
| Openarc Corporate Advisory, Llc | 0.01% | 119,624 | $1,187,866 | $1,217,772 | +$29,906 | +2.52% | |
| Two Sigma Investments, Lp | 0.00% | 140,587 | $1,140,161 | $1,431,176 | +$291,015 | +25.52% | |
| Summerhaven Investment Management, Llc | 0.63% | 114,315 | $1,135,148 | $1,163,727 | +$28,579 | +2.52% | |
| First Trust Advisors Lp | 0.00% | 130,206 | $1,055,970 | $1,325,497 | +$269,527 | +25.52% | |
| Round Rock Advisors Llc | 0.13% | 128,912 | $1,045,476 | $1,312,324 | +$266,848 | +25.52% | |
| Charles Schwab Investment Management Inc | 0.00% | 128,243 | $1,040,051 | $1,305,514 | +$265,463 | +25.52% | |
| Wellington Management Group Llp | 0.00% | 126,091 | $1,022,598 | $1,283,606 | +$261,008 | +25.52% | |
| Strs Ohio | 0.00% | 101,400 | $1,006,902 | $1,032,252 | +$25,350 | +2.52% | |
| Creative Planning | 0.00% | 75,931 | $753,995 | $772,978 | +$18,983 | +2.52% | |
| Evergreen Capital Management Llc | 0.01% | 73,672 | $731,564 | $749,981 | +$18,417 | +2.52% |
Frequently asked questions about PBYI
Who are the largest institutional holders of PBYI?
The largest institutional holders of PBYI reported in the latest SEC Form 13F filings include Acorn Capital Advisors, Llc, Blackrock, Inc., American Century Companies Inc, Acadian Asset Management Llc, and Renaissance Technologies LLC. InsiderSet ranks institutional holders by their latest reported PBYI position.
What is PBYI institutional ownership?
This page tracks PBYI positions reported by institutional investment managers through SEC Form 13F. PUMA BIOTECHNOLOGY INC (PBYI) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own PBYI?
InsiderSet currently tracks 157 institutional managers reporting PBYI holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of PBYI shareholders.
How much PBYI stock do institutions own?
Institutional investment managers disclosed approximately $315.20M in PBYI holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was PBYI institutional ownership last updated?
The latest PBYI institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional PBYI holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its PBYI position after the reporting date.
Are institutions buying or selling PBYI?
Institutional buying and selling can be analyzed by comparing PBYI positions across consecutive 13F reporting periods. InsiderSet's PBYI Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View PBYI ownership changes.
How has PBYI institutional ownership changed over time?
InsiderSet tracks PBYI institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.