PUMA BIOTECHNOLOGY INC (PBYI) Top Institutional Shareholders
PUMA BIOTECHNOLOGY INC (PBYI) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $219.64M in PBYI holdings during the latest filing period.
Acorn Capital Advisors, Llc is currently the largest disclosed institutional shareholder of PBYI tracked by InsiderSet, reporting ownership valued at approximately $26.40M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $29.87M, representing an estimated gain of +13.15% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 59% of the total disclosed PBYI value among the investors covered in this analysis. Major shareholders include Acorn Capital Advisors, Llc, Blackrock, Inc., Renaissance Technologies LLC, and several other long-term asset managers with concentrated positions in PUMA BIOTECHNOLOGY INC (PBYI).
This page ranks the largest institutional PBYI shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
155
Total Reported Value
$219.64M
Largest Holder
Acorn Capital Advisors, Llc
Largest Position
$26.40M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
174
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Acorn Capital Advisors, Llc | 7.50% | 4,131,299 | $26,399,001 | $29,869,292 | +$3,470,291 | +13.15% | |
| Blackrock, Inc. | 0.00% | 3,598,952 | $22,997,304 | $26,020,423 | +$3,023,119 | +13.15% | |
| Renaissance Technologies LLC | Jim Simons | 0.02% | 1,942,413 | $12,412,019 | $14,043,646 | +$1,631,627 | +13.15% |
| American Century Companies Inc | 0.01% | 1,916,346 | $12,245,451 | $13,855,182 | +$1,609,731 | +13.15% | |
| Vanguard Capital Management Llc | 0.00% | 1,817,681 | $11,614,982 | $13,141,834 | +$1,526,852 | +13.15% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,734,649 | $11,084,407 | $12,541,512 | +$1,457,105 | +13.15% | |
| Millennium Management Llc | 0.01% | 1,477,519 | $9,441,346 | $10,682,462 | +$1,241,116 | +13.15% | |
| Dimensional Fund Advisors Lp | 0.00% | 1,436,106 | $9,174,976 | $10,383,046 | +$1,208,070 | +13.17% | |
| O'Shaughnessy Asset Management, Llc | 0.04% | 1,138,169 | $7,272,900 | $8,228,962 | +$956,062 | +13.15% | |
| Geode Capital Management, Llc | 0.00% | 1,017,342 | $6,502,357 | $7,355,383 | +$853,026 | +13.12% | |
| State Street Corp | 0.00% | 917,590 | $5,863,400 | $6,634,176 | +$770,776 | +13.15% | |
| Kennedy Capital Management Llc | 0.12% | 889,601 | $5,684,550 | $6,431,815 | +$747,265 | +13.15% | |
| Aqr Capital Management Llc | 0.00% | 800,194 | $5,113,239 | $5,785,403 | +$672,164 | +13.15% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | 782,798 | $5,002,079 | $5,659,630 | +$657,551 | +13.15% | |
| Bridgeway Capital Management, Llc | 0.10% | 775,341 | $4,954,429 | $5,605,715 | +$651,286 | +13.15% | |
| Ritholtz Wealth Management | 0.09% | 774,308 | $4,947,828 | $5,598,247 | +$650,419 | +13.15% | |
| Goldman Sachs Group Inc | 0.00% | 669,719 | $4,279,504 | $4,842,068 | +$562,564 | +13.15% | |
| Northern Trust Corp | 0.00% | 641,753 | $4,100,802 | $4,639,874 | +$539,072 | +13.15% | |
| Arrowstreet Capital, Limited Partnership | 0.00% | 538,155 | $3,438,810 | $3,890,861 | +$452,051 | +13.15% | |
| Ubs Group Ag | 0.00% | 534,227 | $3,413,710 | $3,862,461 | +$448,751 | +13.15% | |
| Sei Investments Co | 0.00% | 508,182 | $3,247,282 | $3,674,156 | +$426,874 | +13.15% | |
| Morgan Stanley | 0.00% | 359,742 | $2,298,751 | $2,600,935 | +$302,184 | +13.15% | |
| D. E. Shaw & Co., Inc. | 0.00% | 351,235 | $2,244,392 | $2,539,429 | +$295,037 | +13.15% | |
| Globeflex Capital L P | 0.34% | 349,651 | $2,234,270 | $2,527,977 | +$293,707 | +13.15% | |
| Bank Of New York Mellon Corp | 0.00% | 347,881 | $2,222,959 | $2,515,180 | +$292,221 | +13.15% | |
| State Board Of Administration Of Florida Retirement System | 0.00% | 272,890 | $1,743,767 | $1,972,995 | +$229,228 | +13.15% | |
| Prudential Financial Inc | 0.00% | 253,039 | $1,616,919 | $1,829,472 | +$212,553 | +13.15% | |
| Vanguard Fiduciary Trust Co | 0.00% | 251,683 | $1,608,254 | $1,819,668 | +$211,414 | +13.15% | |
| Russell Investments Group, Ltd. | 0.00% | 251,653 | $1,608,063 | $1,819,451 | +$211,388 | +13.15% | |
| Federated Hermes, Inc. | 0.00% | 237,715 | $1,518,999 | $1,718,679 | +$199,680 | +13.15% | |
| Franklin Resources Inc | 0.00% | 215,391 | $1,376,349 | $1,557,277 | +$180,928 | +13.15% | |
| State Of Wisconsin Investment Board | 0.00% | 208,618 | $1,333,069 | $1,508,308 | +$175,239 | +13.15% | |
| Empowered Funds, Llc | 0.01% | 204,041 | $1,303,822 | $1,475,216 | +$171,394 | +13.15% | |
| Panagora Asset Management Inc | 0.00% | 194,887 | $1,245,328 | $1,409,033 | +$163,705 | +13.15% | |
| Fmr Llc | 0.00% | 191,833 | $1,225,813 | $1,386,953 | +$161,140 | +13.15% | |
| Prospera Financial Services Inc | 0.02% | 173,051 | $1,105,760 | $1,251,159 | +$145,399 | +13.15% | |
| Haven Private, Llc | 0.43% | 155,260 | $992,111 | $1,122,530 | +$130,419 | +13.15% | |
| Round Rock Advisors Llc | 0.13% | 128,912 | $823,748 | $932,034 | +$108,286 | +13.15% | |
| First Trust Advisors Lp | 0.00% | 123,513 | $789,248 | $892,999 | +$103,751 | +13.15% | |
| Charles Schwab Investment Management Inc | 0.00% | 115,915 | $740,697 | $838,065 | +$97,368 | +13.15% | |
| Evergreen Capital Management Llc | 0.01% | 96,000 | $613,440 | $694,080 | +$80,640 | +13.15% | |
| Invesco Ltd. | 0.00% | 95,044 | $607,331 | $687,168 | +$79,837 | +13.15% | |
| Strs Ohio | 0.00% | 91,500 | $584,685 | $661,545 | +$76,860 | +13.15% | |
| Openarc Corporate Advisory, Llc | 0.01% | 89,491 | $571,847 | $647,020 | +$75,173 | +13.15% | |
| Nuveen, Llc | 0.00% | 79,101 | $505,456 | $571,900 | +$66,444 | +13.15% | |
| State Of Wyoming | 0.06% | 75,808 | $484,413 | $548,092 | +$63,679 | +13.15% | |
| Winton Group Ltd | 0.01% | 66,333 | $423,868 | $479,588 | +$55,720 | +13.15% | |
| Nomura Asset Management International Inc. | 0.00% | 61,255 | $391,000 | $442,874 | +$51,874 | +13.27% | |
| Entrypoint Capital, Llc | 0.10% | 53,464 | $341,635 | $386,545 | +$44,910 | +13.15% | |
| Rhumbline Advisers | 0.00% | 53,036 | $338,891 | $383,450 | +$44,559 | +13.15% |
Frequently asked questions about PBYI
Who owns the most PBYI stock?
The largest holders of PBYI are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for PUMA BIOTECHNOLOGY INC (PBYI).
Is PBYI widely held by superinvestors?
Many widely followed stocks like PBYI appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly PBYI is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.