PYXS Institutional Ownership & Shareholders
PYXIS ONCOLOGY INC (PYXS) is currently held by 81 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $98.22M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Gordonmd Global Investments Lp is currently the largest disclosed institutional shareholder of PYXS tracked by InsiderSet, reporting ownership valued at approximately $30.17M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $18.15M, representing an estimated loss of -39.87% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 84% of the total disclosed PYXS value among the investors covered in this analysis. Major shareholders include Gordonmd Global Investments Lp, Pfizer Inc, Laurion Capital Management Lp, and several other long-term asset managers with concentrated positions in PYXIS ONCOLOGY INC (PYXS).
This page ranks the largest institutional PYXS shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
81
Total Reported Value
$98.22M
Largest Holder
Gordonmd Global Investments Lp
Largest Position
$30.17M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
105
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Gordonmd Global Investments Lp | 14.60% | 10,024,909 | $30,174,976 | $18,145,085 | -$12,029,891 | -39.87% | |
| Pfizer Inc | 11.43% | 7,032,770 | $19,480,773 | $12,729,314 | -$6,751,459 | -34.66% | |
| Laurion Capital Management Lp | 0.88% | 4,989,888 | $11,626,439 | $9,031,697 | -$2,594,742 | -22.32% | |
| Vanguard Capital Management Llc | 0.00% | 2,075,997 | $6,248,751 | $3,757,555 | -$2,491,196 | -39.87% | |
| Atle Fund Management Ab | 0.78% | 966,459 | $2,909,041 | $1,749,291 | -$1,159,750 | -39.87% | |
| Blackrock, Inc. | 0.00% | 867,934 | $2,612,481 | $1,570,961 | -$1,041,520 | -39.87% | |
| Palo Alto Investors Lp | 0.36% | 864,277 | $2,601,474 | $1,564,341 | -$1,037,133 | -39.87% | |
| Marshall Wace, Llp | 0.00% | 830,544 | $2,499,936 | $1,503,285 | -$996,651 | -39.87% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 772,232 | $2,324,418 | $1,397,740 | -$926,678 | -39.87% |
| Geode Capital Management, Llc | 0.00% | 591,849 | $1,782,698 | $1,071,247 | -$711,451 | -39.91% | |
| Woodline Partners Lp | 0.00% | 523,999 | $1,577,237 | $948,438 | -$628,799 | -39.87% | |
| 683 Capital Management, Llc | 0.13% | 459,367 | $1,382,695 | $831,454 | -$551,241 | -39.87% | |
| Jacobs Levy Equity Management, Inc | 0.00% | 428,606 | $1,290,104 | $775,777 | -$514,327 | -39.87% | |
| Longaeva Partners L.P. | 0.03% | 353,582 | $1,064,282 | $639,983 | -$424,299 | -39.87% | |
| Decheng Capital Llc | 0.13% | 326,810 | $983,698 | $591,526 | -$392,172 | -39.87% | |
| Vanguard Fiduciary Trust Co | 0.00% | 302,986 | $911,988 | $548,405 | -$363,583 | -39.87% | |
| Jane Street Group, Llc | 0.00% | 290,090 | $873,171 | $525,063 | -$348,108 | -39.87% | |
| State Street Corp | 0.00% | 248,837 | $748,999 | $450,395 | -$298,604 | -39.87% | |
| Millennium Management Llc | 0.00% | 233,004 | $701,342 | $421,737 | -$279,605 | -39.87% | |
| Ubs Group Ag | 0.00% | 155,217 | $467,203 | $280,943 | -$186,260 | -39.87% | |
| Bank Of New York Mellon Corp | 0.00% | 133,996 | $403,328 | $242,533 | -$160,795 | -39.87% | |
| Acadian Asset Management Llc | 0.00% | 126,793 | $380,000 | $229,495 | -$150,505 | -39.61% | |
| Northern Trust Corp | 0.00% | 123,959 | $373,117 | $224,366 | -$148,751 | -39.87% | |
| Newedge Wealth, Llc | 0.00% | 116,006 | $349,178 | $209,971 | -$139,207 | -39.87% | |
| Xtx Topco Ltd | 0.00% | 110,939 | $333,926 | $200,800 | -$133,126 | -39.87% | |
| Two Sigma Investments, Lp | 0.00% | 83,961 | $252,723 | $151,969 | -$100,754 | -39.87% | |
| Bridgeway Capital Management, Llc | 0.00% | 81,260 | $244,593 | $147,081 | -$97,512 | -39.87% | |
| Bank Of America Corp | 0.00% | 80,464 | $242,197 | $145,640 | -$96,557 | -39.87% | |
| Stifel Financial Corp | 0.00% | 70,437 | $212,015 | $127,491 | -$84,524 | -39.87% | |
| Mackenzie Financial Corp | 0.00% | 90,747 | $211,441 | $164,252 | -$47,189 | -22.32% | |
| Cable Car Capital, Lp | 0.00% | 61,606 | $185,434 | $111,507 | -$73,927 | -39.87% | |
| Myda Advisors Llc | 0.04% | 50,000 | $150,500 | $90,500 | -$60,000 | -39.87% | |
| Qube Research & Technologies Ltd | 0.00% | 49,932 | $150,295 | $90,377 | -$59,918 | -39.87% | |
| University Of Chicago | 0.03% | 48,731 | $146,680 | $88,203 | -$58,477 | -39.87% | |
| Citadel Advisors Llc | 0.00% | 47,317 | $142,424 | $85,644 | -$56,780 | -39.87% | |
| Quadrature Capital Ltd | 0.00% | 47,067 | $141,672 | $85,191 | -$56,481 | -39.87% | |
| Goldman Sachs Group Inc | 0.00% | 45,900 | $138,159 | $83,079 | -$55,080 | -39.87% | |
| Verdad Advisers, Lp | 0.13% | 44,899 | $135,146 | $81,267 | -$53,879 | -39.87% | |
| Lpl Financial Llc | 0.00% | 43,554 | $131,098 | $78,833 | -$52,265 | -39.87% | |
| J. Derek Lewis & Associates Inc. | 0.02% | 42,000 | $126,420 | $76,020 | -$50,400 | -39.87% | |
| Citigroup Inc | 0.00% | 38,205 | $114,997 | $69,151 | -$45,846 | -39.87% | |
| Simplex Trading, Llc | 0.00% | 37,902 | $114,085 | $68,603 | -$45,482 | -39.87% | |
| Commonwealth Equity Services, Llc | 0.00% | 48,750 | $113,590 | $88,238 | -$25,353 | -22.32% | |
| Point72 Asset Management, L.P. | 0.00% | 37,092 | $111,647 | $67,137 | -$44,510 | -39.87% | |
| Walleye Capital Llc | 0.00% | 36,778 | $110,702 | $66,568 | -$44,134 | -39.87% | |
| Dimensional Fund Advisors Lp | 0.00% | 36,175 | $108,887 | $65,477 | -$43,410 | -39.87% | |
| Morgan Stanley | 0.00% | 33,448 | $100,679 | $60,541 | -$40,138 | -39.87% | |
| Cetera Investment Advisers | 0.00% | 25,000 | $75,250 | $45,250 | -$30,000 | -39.87% | |
| Graham Capital Management, L.P. | 0.00% | 22,708 | $68,351 | $41,101 | -$27,250 | -39.87% | |
| Vanguard Global Advisers, Llc | 0.00% | 21,242 | $63,938 | $38,448 | -$25,490 | -39.87% |
Frequently asked questions about PYXS
Who are the largest institutional holders of PYXS?
The largest institutional holders of PYXS reported in the latest SEC Form 13F filings include Gordonmd Global Investments Lp, Pfizer Inc, Laurion Capital Management Lp, Vanguard Capital Management Llc, and Atle Fund Management Ab. InsiderSet ranks institutional holders by their latest reported PYXS position.
What is PYXS institutional ownership?
This page tracks PYXS positions reported by institutional investment managers through SEC Form 13F. PYXIS ONCOLOGY INC (PYXS) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own PYXS?
InsiderSet currently tracks 81 institutional managers reporting PYXS holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of PYXS shareholders.
How much PYXS stock do institutions own?
Institutional investment managers disclosed approximately $98.22M in PYXS holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was PYXS institutional ownership last updated?
The latest PYXS institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional PYXS holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its PYXS position after the reporting date.
Are institutions buying or selling PYXS?
Institutional buying and selling can be analyzed by comparing PYXS positions across consecutive 13F reporting periods. InsiderSet's PYXS Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View PYXS ownership changes.
How has PYXS institutional ownership changed over time?
InsiderSet tracks PYXS institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.