PYXIS ONCOLOGY INC (PYXS) Institutional Shareholders
PYXIS ONCOLOGY INC (PYXS) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $41.61M in PYXS holdings during the latest filing period.
Pfizer Inc is currently the largest disclosed institutional shareholder of PYXS tracked by InsiderSet, reporting ownership valued at approximately $9.21M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $18.36M, representing an estimated gain of +99.24% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 83% of the total disclosed PYXS value among the investors covered in this analysis. Major shareholders include Pfizer Inc, Laurion Capital Management Lp, Gordonmd Global Investments Lp, and several other long-term asset managers with concentrated positions in PYXIS ONCOLOGY INC (PYXS).
This page ranks the largest institutional PYXS shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
77
Total Reported Value
$41.61M
Largest Holder
Pfizer Inc
Largest Position
$9.21M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
94
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Pfizer Inc | 3.86% | 7,032,770 | $9,212,929 | $18,355,530 | +$9,142,601 | +99.24% | |
| Laurion Capital Management Lp | 0.68% | 4,997,333 | $7,296,106 | $13,043,039 | +$5,746,933 | +78.77% | |
| Gordonmd Global Investments Lp | 4.19% | 4,121,870 | $6,017,930 | $10,758,081 | +$4,740,151 | +78.77% | |
| Vanguard Capital Management Llc | 0.00% | 2,033,510 | $2,968,925 | $5,307,461 | +$2,338,536 | +78.77% | |
| Atle Fund Management Ab | 0.78% | 966,459 | $2,909,041 | $2,522,458 | -$386,583 | -13.29% | |
| Palo Alto Investors Lp | 0.23% | 1,010,510 | $1,475,345 | $2,637,431 | +$1,162,086 | +78.77% | |
| 683 Capital Management, Llc | 0.12% | 896,263 | $1,308,544 | $2,339,246 | +$1,030,702 | +78.77% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 888,680 | $1,297,473 | $2,319,455 | +$1,021,982 | +78.77% |
| Blackrock, Inc. | 0.00% | 788,839 | $1,151,705 | $2,058,870 | +$907,165 | +78.77% | |
| Geode Capital Management, Llc | 0.00% | 598,121 | $873,815 | $1,561,096 | +$687,281 | +78.65% | |
| Longaeva Partners L.P. | 0.04% | 503,214 | $734,692 | $1,313,389 | +$578,697 | +78.77% | |
| Jacobs Levy Equity Management, Inc | 0.00% | 460,997 | $673,056 | $1,203,202 | +$530,146 | +78.77% | |
| Millennium Management Llc | 0.00% | 397,625 | $580,533 | $1,037,801 | +$457,268 | +78.77% | |
| Marshall Wace, Llp | 0.00% | 354,417 | $517,448 | $925,028 | +$407,580 | +78.77% | |
| Decheng Capital Llc | 0.07% | 326,810 | $477,143 | $852,974 | +$375,831 | +78.77% | |
| Jane Street Group, Llc | 0.00% | 304,459 | $444,510 | $794,638 | +$350,128 | +78.77% | |
| Vanguard Fiduciary Trust Co | 0.00% | 300,897 | $439,310 | $785,341 | +$346,031 | +78.77% | |
| Ubs Group Ag | 0.00% | 254,124 | $371,021 | $663,264 | +$292,243 | +78.77% | |
| State Street Corp | 0.00% | 248,837 | $363,302 | $649,465 | +$286,163 | +78.77% | |
| Xtx Topco Ltd | 0.01% | 200,096 | $292,140 | $522,251 | +$230,111 | +78.77% | |
| Bank Of New York Mellon Corp | 0.00% | 133,996 | $195,634 | $349,730 | +$154,096 | +78.77% | |
| Newedge Wealth, Llc | 0.00% | 116,006 | $169,369 | $302,776 | +$133,407 | +78.77% | |
| Northern Trust Corp | 0.00% | 101,948 | $148,844 | $266,084 | +$117,240 | +78.77% | |
| Bridgeway Capital Management, Llc | 0.00% | 81,260 | $118,640 | $212,089 | +$93,449 | +78.77% | |
| Two Sigma Investments, Lp | 0.00% | 73,300 | $107,018 | $191,313 | +$84,295 | +78.77% | |
| Morgan Stanley | 0.00% | 69,688 | $101,744 | $181,886 | +$80,142 | +78.77% | |
| Panagora Asset Management Inc | 0.00% | 69,424 | $101,359 | $181,197 | +$79,838 | +78.77% | |
| Cable Car Capital, Lp | 0.03% | 61,606 | $89,945 | $160,792 | +$70,847 | +78.77% | |
| Citadel Advisors Llc | 0.00% | 61,249 | $89,424 | $159,860 | +$70,436 | +78.77% | |
| Stifel Financial Corp | 0.00% | 50,537 | $73,784 | $131,902 | +$58,118 | +78.77% | |
| Toronto Dominion Bank | 0.00% | 50,000 | $73,000 | $130,500 | +$57,500 | +78.77% | |
| Barclays Plc | 0.00% | 49,825 | $72,745 | $130,043 | +$57,298 | +78.77% | |
| University Of Chicago | 0.02% | 48,731 | $71,147 | $127,188 | +$56,041 | +78.77% | |
| Goldman Sachs Group Inc | 0.00% | 46,920 | $68,503 | $122,461 | +$53,958 | +78.77% | |
| J. Derek Lewis & Associates Inc. | 0.01% | 53,000 | $60,950 | $138,330 | +$77,380 | +126.96% | |
| Susquehanna International Group, Llp | 0.00% | 41,201 | $60,153 | $107,535 | +$47,382 | +78.77% | |
| Commonwealth Equity Services, Llc | 0.00% | 34,755 | $50,740 | $90,711 | +$39,971 | +78.78% | |
| Lpl Financial Llc | 0.00% | 33,554 | $48,989 | $87,576 | +$38,587 | +78.77% | |
| Point72 Asset Management, L.P. | 0.00% | 32,006 | $46,729 | $83,536 | +$36,807 | +78.77% | |
| Cetera Investment Advisers | 0.00% | 27,260 | $39,800 | $71,149 | +$31,349 | +78.77% | |
| Dimensional Fund Advisors Lp | 0.00% | 25,912 | $37,832 | $67,630 | +$29,798 | +78.76% | |
| Graham Capital Management, L.P. | 0.00% | 22,748 | $33,212 | $59,372 | +$26,160 | +78.77% | |
| Maia Wealth Llc | 0.01% | 21,277 | $31,064 | $55,533 | +$24,469 | +78.77% | |
| Vanguard Global Advisers, Llc | 0.00% | 21,242 | $31,013 | $55,442 | +$24,429 | +78.77% | |
| China Universal Asset Management Co., Ltd. | 0.00% | 10,083 | $30,350 | $26,317 | -$4,033 | -13.29% | |
| Catalyst Funds Management Pty Ltd | 0.01% | 20,400 | $29,784 | $53,244 | +$23,460 | +78.77% | |
| Squarepoint Ops Llc | 0.00% | 17,537 | $25,604 | $45,772 | +$20,168 | +78.77% | |
| Bank Of America Corp | 0.00% | 16,807 | $24,538 | $43,866 | +$19,328 | +78.77% | |
| Osaic Holdings, Inc. | 0.00% | 13,721 | $20,032 | $35,812 | +$15,780 | +78.77% | |
| Two Sigma Securities, Llc | 0.00% | 13,474 | $19,672 | $35,167 | +$15,495 | +78.77% |
Frequently asked questions about PYXS
Who owns the most PYXS stock?
The largest holders of PYXS are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for PYXIS ONCOLOGY INC (PYXS).
Is PYXS widely held by superinvestors?
Many widely followed stocks like PYXS appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly PYXS is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.