SUMMIT THERAPEUTICS INC (SMMT) Top Institutional Shareholders
SUMMIT THERAPEUTICS INC (SMMT) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $2.10B in SMMT holdings during the latest filing period.
Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of SMMT tracked by InsiderSet, reporting ownership valued at approximately $689.97M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $512.02M, representing an estimated loss of -25.79% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 78% of the total disclosed SMMT value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Fmr Llc, Blackrock, Inc., and several other long-term asset managers with concentrated positions in SUMMIT THERAPEUTICS INC (SMMT).
This page ranks the largest institutional SMMT shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
221
Total Reported Value
$2.10B
Largest Holder
Baker Bros. Advisors Lp
Largest Position
$689.97M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
166
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors Lp | 3.96% | 36,391,063 | $689,974,554 | $512,022,256 | -$177,952,298 | -25.79% | |
| Fmr Llc | 0.01% | 10,853,199 | $205,776,661 | $152,704,510 | -$53,072,151 | -25.79% | |
| Blackrock, Inc. | 0.00% | 9,653,758 | $183,035,250 | $135,828,375 | -$47,206,875 | -25.79% | |
| State Street Corp | 0.00% | 7,028,160 | $133,253,914 | $98,886,211 | -$34,367,703 | -25.79% | |
| Vanguard Capital Management Llc | 0.00% | 5,711,802 | $108,295,766 | $80,365,054 | -$27,930,712 | -25.79% | |
| Vanguard Portfolio Management Llc | 0.01% | 5,233,252 | $99,222,458 | $73,631,856 | -$25,590,602 | -25.79% | |
| Ubs Group Ag | 0.01% | 3,680,315 | $69,778,773 | $51,782,032 | -$17,996,741 | -25.79% | |
| Geode Capital Management, Llc | 0.00% | 3,315,854 | $62,886,714 | $46,654,066 | -$16,232,648 | -25.81% | |
| D. E. Shaw & Co., Inc. | 0.03% | 2,242,229 | $42,512,661 | $31,548,162 | -$10,964,499 | -25.79% | |
| Morgan Stanley | 0.00% | 1,650,591 | $31,295,209 | $23,223,815 | -$8,071,394 | -25.79% | |
| Apeiron Capital Ltd | 23.22% | 1,309,141 | $24,821,313 | $18,419,614 | -$6,401,699 | -25.79% | |
| Pictet Asset Management Holding Sa | 0.03% | 1,323,179 | $23,962,648 | $18,617,129 | -$5,345,519 | -22.31% | |
| Two Sigma Investments, Lp | 0.02% | 981,185 | $18,603,268 | $13,805,273 | -$4,797,995 | -25.79% | |
| Charles Schwab Investment Management Inc | 0.00% | 960,867 | $18,218,038 | $13,519,399 | -$4,698,639 | -25.79% | |
| Td Asset Management Inc | 0.01% | 956,894 | $18,142,710 | $13,463,499 | -$4,679,211 | -25.79% | |
| Vanguard Fiduciary Trust Co | 0.00% | 934,394 | $17,716,110 | $13,146,924 | -$4,569,186 | -25.79% | |
| Superstring Capital Management Lp | 12.09% | 892,873 | $16,928,872 | $12,562,723 | -$4,366,149 | -25.79% | |
| Point72 Asset Management, L.P. | 0.03% | 784,186 | $14,868,167 | $11,033,497 | -$3,834,670 | -25.79% | |
| Rock Springs Capital Management Lp | 0.79% | 710,000 | $13,461,600 | $9,989,700 | -$3,471,900 | -25.79% | |
| Aberdeen Group Plc | 0.02% | 665,364 | $12,615,301 | $9,361,671 | -$3,253,630 | -25.79% | |
| Squarepoint Ops Llc | 0.03% | 613,877 | $11,639,108 | $8,637,249 | -$3,001,859 | -25.79% | |
| Susquehanna International Group, Llp | 0.01% | 603,933 | $11,450,570 | $8,497,337 | -$2,953,233 | -25.79% | |
| Bank Of America Corp | 0.00% | 598,692 | $11,351,200 | $8,423,596 | -$2,927,604 | -25.79% | |
| Manufacturers Life Insurance Company, The | 0.01% | 592,810 | $11,239,678 | $8,340,837 | -$2,898,841 | -25.79% | |
| Northern Trust Corp | 0.00% | 581,600 | $11,027,135 | $8,183,112 | -$2,844,023 | -25.79% | |
| Balyasny Asset Management L.P. | 0.02% | 548,335 | $10,396,432 | $7,715,073 | -$2,681,359 | -25.79% | |
| Candriam S.C.A. | 0.05% | 540,662 | $10,250,952 | $7,607,114 | -$2,643,838 | -25.79% | |
| Invesco Ltd. | 0.00% | 526,103 | $9,974,913 | $7,402,269 | -$2,572,644 | -25.79% | |
| Marshall Wace, Llp | 0.01% | 475,241 | $9,010,570 | $6,686,641 | -$2,323,929 | -25.79% | |
| Citadel Advisors Llc | 0.01% | 441,743 | $8,375,447 | $6,215,324 | -$2,160,123 | -25.79% | |
| Aqr Capital Management Llc | 0.00% | 443,757 | $8,111,878 | $6,243,661 | -$1,868,217 | -23.03% | |
| Bank Of New York Mellon Corp | 0.00% | 404,679 | $7,672,719 | $5,693,834 | -$1,978,885 | -25.79% | |
| Tudor Investment Corp Et Al | 0.04% | 384,988 | $7,299,372 | $5,416,781 | -$1,882,591 | -25.79% | |
| Wellington Management Group Llp | 0.00% | 362,858 | $6,879,788 | $5,105,412 | -$1,774,376 | -25.79% | |
| Qvt Financial Lp | 0.54% | 360,524 | $6,835,535 | $5,072,573 | -$1,762,962 | -25.79% | |
| Nomura Holdings Inc | 0.05% | 313,981 | $5,953,080 | $4,417,713 | -$1,535,367 | -25.79% | |
| E Fund Management Co., Ltd. | 0.18% | 311,825 | $5,912,202 | $4,387,378 | -$1,524,824 | -25.79% | |
| Goldman Sachs Group Inc | 0.00% | 310,728 | $5,891,403 | $4,371,943 | -$1,519,460 | -25.79% | |
| Rafferty Asset Management, Llc | 0.02% | 259,074 | $4,912,043 | $3,645,171 | -$1,266,872 | -25.79% | |
| Exoduspoint Capital Management, Lp | 0.05% | 256,255 | $4,858,595 | $3,605,508 | -$1,253,087 | -25.79% | |
| Nuveen, Llc | 0.00% | 243,992 | $4,626,089 | $3,432,967 | -$1,193,122 | -25.79% | |
| Deutsche Bank Ag\ | 0.00% | 237,788 | $4,508,460 | $3,345,677 | -$1,162,783 | -25.79% | |
| Schroder Investment Management Group | 0.00% | 251,391 | $4,268,619 | $3,537,071 | -$731,548 | -17.14% | |
| Eversource Wealth Advisors, Llc | 0.13% | 25,069 | $4,224,352 | $352,721 | -$3,871,631 | -91.65% | |
| Woodline Partners Lp | 0.02% | 214,507 | $4,067,053 | $3,018,113 | -$1,048,940 | -25.79% | |
| Citigroup Inc | 0.00% | 199,133 | $3,775,562 | $2,801,801 | -$973,761 | -25.79% | |
| Griffin Asset Management, Inc. | 0.41% | 191,872 | $3,637,893 | $2,699,639 | -$938,254 | -25.79% | |
| China Universal Asset Management Co., Ltd. | 0.20% | 137,596 | $2,608,820 | $1,935,976 | -$672,844 | -25.79% | |
| Polymer Capital Management (Hk) Ltd | 0.35% | 133,034 | $2,522,325 | $1,871,788 | -$650,537 | -25.79% | |
| Voya Investment Management Llc | 0.00% | 130,237 | $2,469,293 | $1,832,435 | -$636,858 | -25.79% |
Frequently asked questions about SMMT
Who owns the most SMMT stock?
The largest holders of SMMT are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for SUMMIT THERAPEUTICS INC (SMMT).
Is SMMT widely held by superinvestors?
Many widely followed stocks like SMMT appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly SMMT is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.