SMMT Institutional Ownership & Shareholders
SUMMIT THERAPEUTICS INC (SMMT) is currently held by 250 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $1.99B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of SMMT tracked by InsiderSet, reporting ownership valued at approximately $477.70M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $525.57M, representing an estimated gain of +10.02% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 66% of the total disclosed SMMT value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Fmr Llc, State Street Corp, and several other long-term asset managers with concentrated positions in SUMMIT THERAPEUTICS INC (SMMT).
This page ranks the largest institutional SMMT shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
250
Total Reported Value
$1.99B
Largest Holder
Baker Bros. Advisors Lp
Largest Position
$477.70M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
76
Funds Exiting Positions
2
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors Lp | 2.39% | 32,786,348 | $477,697,090 | $525,565,158 | +$47,868,068 | +10.02% | |
| Fmr Llc | 0.01% | 10,043,947 | $146,340,308 | $161,004,470 | +$14,664,162 | +10.02% | |
| State Street Corp | 0.00% | 9,536,796 | $138,951,118 | $152,874,840 | +$13,923,722 | +10.02% | |
| Blackrock, Inc. | 0.00% | 9,529,041 | $138,838,127 | $152,750,527 | +$13,912,400 | +10.02% | |
| Vanguard Capital Management Llc | 0.00% | 5,734,484 | $83,551,432 | $91,923,779 | +$8,372,347 | +10.02% | |
| Ubs Group Ag | 0.01% | 5,233,798 | $76,256,437 | $83,897,782 | +$7,641,345 | +10.02% | |
| Vanguard Portfolio Management Llc | 0.00% | 5,042,190 | $73,464,708 | $80,826,306 | +$7,361,598 | +10.02% | |
| Goldman Sachs Group Inc | 0.01% | 4,513,399 | $65,760,228 | $72,349,786 | +$6,589,558 | +10.02% | |
| Price T Rowe Associates Inc | 0.01% | 3,893,820 | $56,734,000 | $62,417,935 | +$5,683,935 | +10.02% | |
| Point72 Asset Management, L.P. | 0.08% | 3,697,803 | $53,876,990 | $59,275,782 | +$5,398,792 | +10.02% | |
| Geode Capital Management, Llc | 0.00% | 3,427,263 | $49,950,115 | $54,939,026 | +$4,988,911 | +9.99% | |
| Millennium Management Llc | 0.02% | 2,349,081 | $34,226,110 | $37,655,768 | +$3,429,658 | +10.02% | |
| Adage Capital Partners Gp, L.L.C. | 0.04% | 1,989,591 | $28,988,341 | $31,893,144 | +$2,904,803 | +10.02% | |
| Balyasny Asset Management L.P. | 0.05% | 1,904,254 | $27,744,981 | $30,525,192 | +$2,780,211 | +10.02% | |
| Citadel Advisors Llc | 0.01% | 1,725,716 | $25,143,682 | $27,663,227 | +$2,519,545 | +10.02% | |
| Aberdeen Group Plc | 0.03% | 1,693,626 | $24,676,131 | $27,148,825 | +$2,472,694 | +10.02% | |
| Squarepoint Ops Llc | 0.04% | 1,590,736 | $23,177,024 | $25,499,498 | +$2,322,474 | +10.02% | |
| Morgan Stanley | 0.00% | 1,450,019 | $21,126,777 | $23,243,805 | +$2,117,028 | +10.02% | |
| Norges Bank | 0.00% | 1,382,519 | $20,143,302 | $22,161,780 | +$2,018,478 | +10.02% | |
| Logos Global Management Lp | 0.85% | 1,350,000 | $19,669,500 | $21,640,500 | +$1,971,000 | +10.02% | |
| Octagon Capital Advisors Lp | 1.67% | 1,250,000 | $18,212,500 | $20,037,500 | +$1,825,000 | +10.02% | |
| D. E. Shaw & Co., Inc. | 0.01% | 1,243,556 | $18,118,611 | $19,934,203 | +$1,815,592 | +10.02% | |
| Kynam Capital Management, Lp | 0.97% | 1,200,000 | $17,484,000 | $19,236,000 | +$1,752,000 | +10.02% | |
| Pictet Asset Management Holding Sa | 0.02% | 1,134,299 | $16,434,565 | $18,182,813 | +$1,748,248 | +10.64% | |
| Charles Schwab Investment Management Inc | 0.00% | 976,851 | $14,232,719 | $15,658,922 | +$1,426,203 | +10.02% | |
| Vanguard Fiduciary Trust Co | 0.00% | 966,585 | $14,083,143 | $15,494,358 | +$1,411,215 | +10.02% | |
| Apeiron Capital Ltd | 9.00% | 961,866 | $14,014,388 | $15,418,712 | +$1,404,324 | +10.02% | |
| Bank Of America Corp | 0.00% | 864,983 | $12,602,803 | $13,865,677 | +$1,262,874 | +10.02% | |
| Schroder Investment Management Group | 0.01% | 835,963 | $11,970,990 | $13,400,487 | +$1,429,497 | +11.94% | |
| Rock Springs Capital Management Lp | 0.51% | 715,000 | $10,417,550 | $11,461,450 | +$1,043,900 | +10.02% | |
| Citigroup Inc | 0.00% | 714,000 | $10,402,980 | $11,445,420 | +$1,042,440 | +10.02% | |
| Two Sigma Investments, Lp | 0.01% | 696,714 | $10,151,123 | $11,168,325 | +$1,017,202 | +10.02% | |
| Northern Trust Corp | 0.00% | 633,794 | $9,234,379 | $10,159,718 | +$925,339 | +10.02% | |
| Simplify Asset Management Inc. | 0.15% | 510,106 | $8,625,892 | $8,176,999 | -$448,893 | -5.20% | |
| Marshall Wace, Llp | 0.01% | 577,190 | $8,409,659 | $9,252,356 | +$842,697 | +10.02% | |
| Aqr Capital Management Llc | 0.00% | 542,178 | $7,899,533 | $8,691,113 | +$791,580 | +10.02% | |
| Candriam S.C.A. | 0.03% | 532,432 | $7,750,071 | $8,534,885 | +$784,814 | +10.13% | |
| Susquehanna International Group, Llp | 0.01% | 521,339 | $7,595,909 | $8,357,064 | +$761,155 | +10.02% | |
| Elmind Capital, Lp | 1.81% | 493,820 | $7,194,957 | $7,915,935 | +$720,978 | +10.02% | |
| Wellington Management Group Llp | 0.00% | 441,934 | $6,438,979 | $7,084,202 | +$645,223 | +10.02% | |
| Bank Of New York Mellon Corp | 0.00% | 431,299 | $6,284,022 | $6,913,723 | +$629,701 | +10.02% | |
| Worldquant Millennium Advisors Llc | 0.02% | 431,028 | $6,280,078 | $6,909,379 | +$629,301 | +10.02% | |
| Td Asset Management Inc | 0.01% | 426,084 | $6,208,044 | $6,830,127 | +$622,083 | +10.02% | |
| Invesco Ltd. | 0.00% | 416,847 | $6,073,461 | $6,682,057 | +$608,596 | +10.02% | |
| Jump Financial, Llc | 0.05% | 389,618 | $5,676,734 | $6,245,577 | +$568,843 | +10.02% | |
| Griffin Asset Management, Inc. | 0.59% | 324,017 | $5,479,127 | $5,193,993 | -$285,134 | -5.20% | |
| Qvt Financial Lp | 0.34% | 360,524 | $5,252,835 | $5,779,200 | +$526,365 | +10.02% | |
| Ghisallo Capital Management Llc | 0.10% | 350,000 | $5,099,500 | $5,610,500 | +$511,000 | +10.02% | |
| Manufacturers Life Insurance Company, The | 0.00% | 298,000 | $4,341,860 | $4,776,940 | +$435,080 | +10.02% | |
| Nuveen, Llc | 0.00% | 294,867 | $4,296,212 | $4,726,718 | +$430,506 | +10.02% |
Frequently asked questions about SMMT
Who are the largest institutional holders of SMMT?
The largest institutional holders of SMMT reported in the latest SEC Form 13F filings include Baker Bros. Advisors Lp, Fmr Llc, State Street Corp, Blackrock, Inc., and Vanguard Capital Management Llc. InsiderSet ranks institutional holders by their latest reported SMMT position.
What is SMMT institutional ownership?
This page tracks SMMT positions reported by institutional investment managers through SEC Form 13F. SUMMIT THERAPEUTICS INC (SMMT) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own SMMT?
InsiderSet currently tracks 250 institutional managers reporting SMMT holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of SMMT shareholders.
How much SMMT stock do institutions own?
Institutional investment managers disclosed approximately $1.99B in SMMT holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was SMMT institutional ownership last updated?
The latest SMMT institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional SMMT holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its SMMT position after the reporting date.
Are institutions buying or selling SMMT?
Institutional buying and selling can be analyzed by comparing SMMT positions across consecutive 13F reporting periods. InsiderSet's SMMT Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View SMMT ownership changes.
How has SMMT institutional ownership changed over time?
InsiderSet tracks SMMT institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.