ALNYLAM PHARMACEUTICALS INC (ALNY) Institutional Shareholders
ALNYLAM PHARMACEUTICALS INC (ALNY) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $37.95B in ALNY holdings during the latest filing period.
Fmr Llc is currently the largest disclosed institutional shareholder of ALNY tracked by InsiderSet, reporting ownership valued at approximately $4.52B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $3.44B, representing an estimated loss of -24.04% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed ALNY value among the investors covered in this analysis. Major shareholders include Fmr Llc, Capital World Investors, Blackrock, Inc., and several other long-term asset managers with concentrated positions in ALNYLAM PHARMACEUTICALS INC (ALNY).
This page ranks the largest institutional ALNY shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
772
Total Reported Value
$37.95B
Largest Holder
Fmr Llc
Largest Position
$4.52B
Insider Transactions (90d)
15
Latest Filing Quarter
Q2 2026
New Institutional Positions
43
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.20% | 15,023,962 | $4,522,663,249 | $3,435,228,911 | -$1,087,434,338 | -24.04% | |
| Capital World Investors | 0.40% | 11,144,846 | $3,354,715,611 | $2,548,269,038 | -$806,446,573 | -24.04% | |
| Blackrock, Inc. | 0.05% | 10,907,675 | $3,283,537,489 | $2,494,039,889 | -$789,497,600 | -24.04% | |
| Capital Research Global Investors | 0.41% | 9,750,699 | $2,935,115,324 | $2,229,497,326 | -$705,617,998 | -24.04% | |
| Vanguard Portfolio Management Llc | 0.09% | 6,538,390 | $1,968,251,542 | $1,495,002,874 | -$473,248,669 | -24.04% | |
| Vanguard Capital Management Llc | 0.04% | 6,029,478 | $1,815,053,762 | $1,378,640,145 | -$436,413,617 | -24.04% | |
| Invesco Ltd. | 0.09% | 3,754,318 | $1,130,162,348 | $858,424,811 | -$271,737,537 | -24.04% | |
| State Street Corp | 0.03% | 3,555,689 | $1,070,369,060 | $813,008,290 | -$257,360,770 | -24.04% | |
| Geode Capital Management, Llc | 0.04% | 2,635,840 | $791,345,610 | $602,684,816 | -$188,660,794 | -23.84% | |
| Jpmorgan Chase & Co | 0.05% | 2,675,517 | $785,318,336 | $611,756,962 | -$173,561,374 | -22.10% | |
| Baillie Gifford & Co | 0.67% | 2,439,889 | $734,479,786 | $557,880,620 | -$176,599,166 | -24.04% | |
| Norges Bank | 0.07% | 2,271,813 | $683,883,867 | $519,450,042 | -$164,433,825 | -24.04% | |
| Wellington Management Group Llp | 0.11% | 2,110,407 | $635,295,819 | $482,544,561 | -$152,751,258 | -24.04% | |
| Orbis Allan Gray Ltd | 2.06% | 1,987,407 | $598,269,130 | $454,420,611 | -$143,848,519 | -24.04% | |
| Dodge & Cox Stock Fund | V. D. Dodge, E. M. Cox | 0.31% | 1,955,393 | $588,631,955 | $447,100,609 | -$141,531,346 | -24.04% |
| Two Sigma Investments, Lp | 0.42% | 1,875,937 | $564,713,315 | $428,932,995 | -$135,780,320 | -24.04% | |
| American Century Companies Inc | 0.25% | 1,853,956 | $558,098,292 | $423,907,039 | -$134,191,253 | -24.04% | |
| Clearbridge Investments, Llc | 0.31% | 1,259,483 | $379,142,285 | $287,980,788 | -$91,161,497 | -24.04% | |
| D. E. Shaw & Co., Inc. | 0.21% | 1,104,109 | $332,369,932 | $252,454,523 | -$79,915,409 | -24.04% | |
| Morgan Stanley | 0.02% | 1,032,150 | $310,709,115 | $236,001,098 | -$74,708,018 | -24.04% | |
| Bank Of America Corp | 0.02% | 994,476 | $299,367,191 | $227,386,937 | -$71,980,254 | -24.04% | |
| Legal & General Group Plc | 0.06% | 924,561 | $278,320,594 | $211,400,873 | -$66,919,721 | -24.04% | |
| Manufacturers Life Insurance Company, The | 0.21% | 893,795 | $269,059,154 | $204,366,227 | -$64,692,927 | -24.04% | |
| Northern Trust Corp | 0.03% | 886,900 | $266,983,506 | $202,789,685 | -$64,193,821 | -24.04% | |
| Royal Bank Of Canada | 0.04% | 875,859 | $263,661,000 | $200,265,160 | -$63,395,840 | -24.04% | |
| Vanguard Fiduciary Trust Co | 0.06% | 862,782 | $259,723,265 | $197,275,104 | -$62,448,161 | -24.04% | |
| Deep Track Capital, Lp | 3.66% | 825,000 | $248,349,750 | $188,636,250 | -$59,713,500 | -24.04% | |
| Deutsche Bank Ag\ | 0.07% | 815,400 | $245,459,862 | $186,441,210 | -$59,018,652 | -24.04% | |
| Qube Research & Technologies Ltd | 0.27% | 798,715 | $240,437,176 | $182,626,185 | -$57,810,991 | -24.04% | |
| Charles Schwab Investment Management Inc | 0.03% | 755,377 | $227,391,139 | $172,716,951 | -$54,674,188 | -24.04% | |
| Sixth Street Partners Management Company, L.P. | 0.03% | 755,377 | $227,391,139 | $172,716,951 | -$54,674,188 | -24.04% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.05% | 677,519 | $224,170,712 | $154,914,719 | -$69,255,993 | -30.89% | |
| Los Angeles Capital Management Llc | 0.81% | 729,635 | $219,642,021 | $166,831,043 | -$52,810,978 | -24.04% | |
| Aqr Capital Management Llc | 0.08% | 728,039 | $218,994,064 | $166,466,117 | -$52,527,947 | -23.99% | |
| Federated Hermes, Inc. | 0.31% | 719,905 | $216,713,003 | $164,606,278 | -$52,106,725 | -24.04% | |
| Ubs Group Ag | 0.03% | 627,004 | $188,747,013 | $143,364,465 | -$45,382,548 | -24.04% | |
| Amundi | 0.05% | 617,471 | $185,877,295 | $141,184,744 | -$44,692,551 | -24.04% | |
| Loomis Sayles & Co L P | 0.22% | 580,187 | $174,653,692 | $132,659,758 | -$41,993,934 | -24.04% | |
| Goldman Sachs Group Inc | 0.02% | 574,757 | $173,019,032 | $131,418,188 | -$41,600,844 | -24.04% | |
| Bank Of New York Mellon Corp | 0.02% | 492,071 | $148,128,276 | $112,512,034 | -$35,616,242 | -24.04% | |
| Polar Capital Holdings Plc | 0.41% | 482,751 | $145,322,534 | $110,381,016 | -$34,941,518 | -24.04% | |
| Paradigm Biocapital Advisors Lp | 2.71% | 480,000 | $144,494,400 | $109,752,000 | -$34,742,400 | -24.04% | |
| First Trust Advisors Lp | 0.07% | 421,534 | $126,894,361 | $96,383,749 | -$30,510,612 | -24.04% | |
| Raymond James Financial Inc | 0.03% | 392,799 | $118,244,275 | $89,813,491 | -$28,430,784 | -24.04% | |
| Dimensional Fund Advisors Lp | 0.02% | 392,022 | $117,970,419 | $89,635,830 | -$28,334,589 | -24.02% | |
| Swiss National Bank | 0.06% | 374,080 | $112,609,302 | $85,533,392 | -$27,075,910 | -24.04% | |
| Massachusetts Financial Services Co | 0.03% | 350,560 | $105,524,729 | $80,155,544 | -$25,369,185 | -24.04% | |
| Canada Pension Plan Investment Board | 0.06% | 334,246 | $100,618,073 | $76,425,348 | -$24,192,725 | -24.04% | |
| Sumitomo Mitsui Trust Group, Inc. | 0.06% | 325,379 | $97,948,840 | $74,397,908 | -$23,550,932 | -24.04% | |
| Millennium Management Llc | 0.06% | 316,001 | $95,125,781 | $72,253,629 | -$22,872,152 | -24.04% |
Frequently asked questions about ALNY
Who owns the most ALNY stock?
The largest holders of ALNY are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ALNYLAM PHARMACEUTICALS INC (ALNY).
Is ALNY widely held by superinvestors?
Many widely followed stocks like ALNY appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ALNY is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.