Most bought healthcare stocks in Q4 2025
See which Healthcare stocks institutional investors increased the most in Q4 2025, measured as net growth in reported share positions from Q3 2025 into Q4 2025. Notable additions at the top of this list include APPLIED THERAPEUTICS INC (APLT), TENET HEALTHCARE CORP (THC), EDITAS MEDICINE INC (EDIT), ESPERION THERAPEUTICS INC (ESPR). These rankings are based on SEC 13F filings from the investors we track.
| Symbol | Name | Net shares | Net value | New | Added | Trimmed | Sold out | Holding now |
|---|---|---|---|---|---|---|---|---|
| APLT | APPLIED THERAPEUTICS INC | 2,706,156 | $270.62K | 1 | 0 | 0 | 0 | 1 |
| THC | TENET HEALTHCARE CORP | 1,778,517 | $353.39M | 1 | 0 | 0 | 2 | 1 |
| EDIT | EDITAS MEDICINE INC | 1,762,378 | $1.80M | 0 | 1 | 0 | 0 | 1 |
| ESPR | ESPERION THERAPEUTICS INC | 1,536,992 | $6.50M | 1 | 1 | 0 | 0 | 2 |
| WEAV | WEAVE COMMUNICATIONS INC | 1,429,255 | $13.19M | 0 | 2 | 0 | 1 | 2 |
| OCGN | OCUGEN INC | 1,410,200 | $1.82M | 0 | 1 | 0 | 0 | 1 |
| MGNX | MACROGENICS INC | 1,207,408 | $1.82M | 0 | 1 | 0 | 0 | 1 |
| FATE | FATE THERAPEUTICS INC | 1,098,366 | $729.03K | 0 | 1 | 0 | 0 | 1 |
| GUTS | FRACTYL HEALTH INC | 1,086,351 | $2.86M | 0 | 1 | 0 | 0 | 1 |
| KURA | KURA ONCOLOGY INC | 1,056,103 | $12.31M | 1 | 1 | 0 | 0 | 2 |
| CNC | CENTENE CORP | 1,031,355 | $42.62M | 1 | 1 | 0 | 1 | 2 |
| IVVD | INVIVYD INC | 1,026,620 | $2.54M | 1 | 0 | 0 | 0 | 1 |
| AIRS | AIRSCULPT TECHNOLOGIES INC | 1,005,464 | $1.99M | 1 | 0 | 0 | 0 | 1 |
| AGL | AGILON HEALTH INC | 883,808 | $101.09K | 0 | 1 | 0 | 1 | 1 |
| OPCH | OPTION CARE HEALTH INC | 878,765 | $63.24M | 0 | 1 | 1 | 0 | 2 |
| ADMA | ADMA BIOLOGICS INC | 864,233 | $25.68M | 1 | 0 | 1 | 0 | 2 |
| CRBU | CARIBOU BIOSCIENCES INC | 859,436 | $788.99K | 0 | 1 | 0 | 0 | 1 |
| MNKD | MANNKIND CORP | 857,856 | $5.13M | 0 | 1 | 0 | 1 | 1 |
| ISRG | INTUITIVE SURGICAL INC | 822,347 | $506.99M | 3 | 1 | 1 | 4 | 5 |
| OCUL | OCULAR THERAPEUTIX INC | 791,200 | $9.61M | 1 | 0 | 0 | 0 | 1 |
| BTSG | BRIGHTSPRING HEALTH SERVICES | 776,975 | $32.73M | 0 | 1 | 0 | 0 | 1 |
| CCCC | C4 THERAPEUTICS INC | 665,630 | $980.90K | 0 | 1 | 0 | 0 | 1 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 651,000 | $1.78M | 1 | 0 | 0 | 0 | 1 |
| GMAB | GENMAB A/S -SP ADR | 644,911 | $20.23M | 0 | 1 | 0 | 1 | 1 |
| GOVX | GEOVAX LABS INC | 606,528 | $103.72K | 1 | 0 | 0 | 0 | 1 |
| ALEC | ALECTOR INC | 594,500 | -$401.39K | 0 | 1 | 0 | 0 | 1 |
| MRNA | MODERNA INC | 568,400 | $16.76M | 1 | 0 | 0 | 0 | 1 |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 558,390 | $381.77K | 0 | 1 | 0 | 0 | 1 |
| MDXG | MIMEDX GROUP INC | 558,281 | $3.07M | 0 | 2 | 0 | 0 | 2 |
| ORIC | ORIC PHARMACEUTICALS INC | 558,215 | -$20.60M | 0 | 1 | 1 | 0 | 2 |
| NKTX | NKARTA INC | 556,945 | $778.43K | 0 | 1 | 0 | 0 | 1 |
| SPRY | ARS PHARMACEUTICALS INC | 556,237 | $6.48M | 1 | 0 | 0 | 0 | 1 |
| LUCD | LUCID DIAGNOSTICS INC | 532,894 | $604.35K | 0 | 1 | 0 | 0 | 1 |
| MEIP | MEI PHARMA INC | 522,741 | -$430.53K | 0 | 1 | 0 | 0 | 1 |
| ATOS | ATOSSA THERAPEUTICS INC | 514,175 | -$125.62K | 0 | 1 | 0 | 0 | 1 |
| LCTX | LINEAGE CELL THERAPEUTICS IN | 499,167 | $795.50K | 0 | 1 | 0 | 0 | 1 |
| TVTX | TRAVERE THERAPEUTICS INC | 494,665 | $43.97M | 0 | 1 | 0 | 0 | 1 |
| AGEN | AGENUS INC | 477,346 | $1.45M | 0 | 1 | 0 | 0 | 1 |
| STIM | NEURONETICS INC | 474,900 | $655.36K | 1 | 0 | 0 | 0 | 1 |
| BHC | BAUSCH HEALTH COS INC | 473,361 | $4.58M | 0 | 2 | 0 | 1 | 3 |
| DOCS | DOXIMITY INC-CLASS A | 467,656 | -$81.72M | 0 | 2 | 0 | 2 | 2 |
| MGX | METAGENOMI INC | 461,400 | $622.22K | 0 | 1 | 0 | 0 | 1 |
| COGT | COGENT BIOSCIENCES INC | 456,100 | $21.13M | 0 | 1 | 0 | 0 | 1 |
| KROS | KEROS THERAPEUTICS INC | 436,986 | $9.60M | 0 | 1 | 0 | 0 | 1 |
| CDXS | CODEXIS INC | 426,999 | $444.51K | 0 | 1 | 0 | 0 | 1 |
| SHC | SOTERA HEALTH CO | 426,778 | $7.53M | 1 | 0 | 0 | 0 | 1 |
| REPL | REPLIMUNE GROUP INC | 405,053 | $3.94M | 1 | 0 | 0 | 0 | 1 |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 399,608 | $5.78M | 0 | 1 | 0 | 0 | 1 |
| PBH | PRESTIGE CONSUMER HEALTHCARE | 366,341 | $19.88M | 0 | 1 | 1 | 1 | 3 |
| MYGN | MYRIAD GENETICS INC | 357,700 | $2.18M | 0 | 1 | 0 | 0 | 1 |
Frequently asked questions about Most bought healthcare stocks in Q4 2025
What are the most bought Healthcare stocks in Q4 2025?
The most bought healthcare stocks in Q4 2025 are those with the largest increase in reported share counts across tracked institutional investors compared to Q3 2025, based on SEC 13F filings.
Which healthcare stocks did institutional investors added to the most in Q4 2025?
Among the managers we track, net additions were largest in companies such as APPLIED THERAPEUTICS INC (APLT), TENET HEALTHCARE CORP (THC), EDITAS MEDICINE INC (EDIT), based on aggregated 13F data.
How is institutional buying calculated?
Buying is calculated by summing the net increase in shares reported by tracked investors between two consecutive quarterly 13F snapshots (compared to Q3 2025).
Does this include all institutional owners?
These rankings are based on a subset of tracked institutional investors who file SEC 13F reports. While not exhaustive, the dataset includes many of the largest and most influential funds.
Are these trades real-time?
No. 13F filings are reported quarterly and may be delayed by up to 45 days. The data reflects positions at the end of the reporting period, not real-time trading activity.