CASTLE BIOSCIENCES INC (CSTL) Institutional Ownership Changes & 13F Activity

CASTLE BIOSCIENCES INC (CSTL). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Portolan Capital Management, Llc, Jefferies Financial Group Inc., Point72 Asset Management, L.P., Kennedy Capital Management Llc, and Palisade Capital Management, Lp.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Envestnet Asset Management IncSell-6,708-10.8%55,157$1.32MQ2 2026Sep 23, 2026
State Street CorpBuy+53,000+6.9%822,079$19.63MQ2 2026Sep 22, 2026
Manufacturers Life Insurance Company, TheBuy+105+0.8%12,543$299.15KQ2 2026Sep 09, 2026
Citadel Advisors LlcBuy+144,376+119.3%265,353$6.33MQ2 2026Sep 02, 2026
Allianz Asset Management GmbhBuy+67,934+8.4%879,258$20.97MQ2 2026Sep 02, 2026
California State Teachers Retirement SystemBuy+10,289+37.4%37,802$901.58KQ2 2026Aug 24, 2026
Jefferies Financial Group Inc.Buy+647,391—647,391$15.44MQ2 2026Aug 17, 2026
Empowered Funds, LlcBuy+10,154+7.7%142,338$3.39MQ2 2026Aug 17, 2026
Portolan Capital Management, LlcSell-1,021,465-75.6%328,818$7.84MQ2 2026Aug 14, 2026
Point72 Asset Management, L.P.Buy+357,317—357,317$8.52MQ2 2026Aug 14, 2026
Kennedy Capital Management LlcBuy+348,371—348,371$8.31MQ2 2026Aug 14, 2026
Palisade Capital Management, LpSell-303,953-56.7%231,931$5.53MQ2 2026Aug 14, 2026
Tudor Investment Corp Et AlSell-208,520-93.5%14,462$344.92KQ2 2026Aug 14, 2026
Two Sigma Investments, LpSell-148,466-59.7%100,374$2.39MQ2 2026Aug 14, 2026
Millennium Management LlcSell-147,950-41.9%205,369$4.90MQ2 2026Aug 14, 2026
Summit Partners Public Asset Management, LlcSell-115,813-12.3%824,872$19.67MQ2 2026Aug 14, 2026
Aqr Capital Management LlcBuy+101,687+156.7%166,567$3.97MQ2 2026Aug 14, 2026
Hrt Financial LpBuy+99,995+630.6%115,853$2.76MQ2 2026Aug 14, 2026
D. E. Shaw & Co., Inc.Sell-99,177-46.8%112,789$2.69MQ2 2026Aug 14, 2026
Trexquant Investment LpBuy+75,677+58.0%206,111$4.92MQ2 2026Aug 14, 2026
Man Group PlcBuy+61,623+130.7%108,761$2.59MQ2 2026Aug 14, 2026
Invesco Ltd.Buy+54,888—54,888$1.31MQ2 2026Aug 14, 2026
Sei Investments CoBuy+39,387+112.4%74,433$1.78MQ2 2026Aug 14, 2026
Bridgeway Capital Management, LlcSell-33,846-13.3%221,338$5.28MQ2 2026Aug 14, 2026
Bank Of America CorpBuy+30,935+45.6%98,745$2.36MQ2 2026Aug 14, 2026
Qube Research & Technologies LtdBuy+29,717+5.3%589,300$14.05MQ2 2026Aug 14, 2026
Schonfeld Strategic Advisors LlcSell-22,483-53.0%19,930$475.33KQ2 2026Aug 14, 2026
Rtw Investments, LpBuy+20,000+0.7%2,778,335$66.26MQ2 2026Aug 14, 2026
Xtx Topco LtdBuy+19,640+96.8%39,923$952.16KQ2 2026Aug 14, 2026
Parkman Healthcare Partners LlcBuy+18,641+14.8%144,791$3.45MQ2 2026Aug 14, 2026
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Frequently asked questions about CSTL activity

  • Which institutional owners are buying CSTL?

    Institutional owners buying CSTL include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in CSTL activity?

    "Buy" means an investor increased their reported position in CSTL compared to the prior reporting period. This reflects growing exposure to CASTLE BIOSCIENCES INC (CSTL) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in CSTL increasing?

    Institutional interest in CSTL can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.