CYTOKINETICS INC (CYTK) Stock Institutional Trading Activity


CYTOKINETICS INC (CYTK) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC, Polen Capital Management, and Sequoia Financial Advisors. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Polen Capital ManagementBuy9,5849,584$608,967
Q4 2025Renaissance Technologies LLCSell-117,900172,067$10,933,137
Q3 2025Renaissance Technologies LLCBuy279,800289,967$15,936,586
Q2 2025Renaissance Technologies LLCSell-110,50010,167$335,918
Q1 2025Renaissance Technologies LLCSell-71,500120,667$4,849,607
Q4 2024Renaissance Technologies LLCSell-52,200192,167$9,039,536
Q3 2024Renaissance Technologies LLCSell-226,600244,367$12,902,578
Q2 2024Renaissance Technologies LLCBuy105,000470,967$25,516,992
Q1 2024Renaissance Technologies LLCBuy330,000365,967$25,658
Q4 2023Renaissance Technologies LLCSell-37,70035,967$3,003
Q4 2023Sequoia Financial AdvisorsBuy3,1473,147$262,744
Q4 2022Renaissance Technologies LLCSell-264,70073,667$3,375
Q3 2021Renaissance Technologies LLCBuy267,600338,367$12,093
Q2 2021Renaissance Technologies LLCSell-30070,767$1,400
Q2 2020Renaissance Technologies LLCSell-82,70071,067$1,675
Q4 2019Renaissance Technologies LLCBuy83,467153,767$1,631
Q3 2019Renaissance Technologies LLCSell-298,00070,300$800
Q2 2019Renaissance Technologies LLCBuy93,000368,300$4,143
Q1 2019Renaissance Technologies LLCBuy256,100275,300$2,227
Q4 2018Renaissance Technologies LLCSell-165,27919,200$121
Q1 2016Renaissance Technologies LLCSell-334,799184,479$1,301
Q4 2015Renaissance Technologies LLCBuy299,578519,278$5,432
Q3 2015Renaissance Technologies LLCBuy147,300219,700$1,470
Q2 2015Renaissance Technologies LLCBuy2,93372,400$487
Q1 2015Renaissance Technologies LLCSell-428,69469,467$471
Q3 2014Renaissance Technologies LLCBuy240,624498,161$1,754
Q2 2014Renaissance Technologies LLCBuy69,470257,537$1,231
Q1 2014Renaissance Technologies LLCSell-147,200188,067$1,787
Q4 2013Renaissance Technologies LLCBuy335,267335,267$2,179

Frequently asked questions about CYTK activity

  • Which institutional owners are buying CYTK?

    Institutional owners buying CYTK include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in CYTK activity?

    "Buy" means an investor increased their reported position in CYTK compared to the prior reporting period. This reflects growing exposure to CYTOKINETICS INC (CYTK) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in CYTK increasing?

    Institutional interest in CYTK can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.