IOVANCE BIOTHERAPEUTICS INC (IOVA) Stock Institutional Trading Activity


IOVANCE BIOTHERAPEUTICS INC (IOVA) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC and ARK Invest. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Renaissance Technologies LLCSell-4,236,200651,000$1,777,230
Q2 2025Renaissance Technologies LLCBuy1,375,8004,887,200$8,405,984
Q1 2025Renaissance Technologies LLCBuy2,285,0003,511,400$11,692,962
Q3 2023Renaissance Technologies LLCSell-506,3001,226,400$5,580
Q2 2023ARK InvestSell-33,179775,787$5,461,542
Q2 2023Renaissance Technologies LLCSell-142,8001,732,700$12,198
Q1 2023ARK InvestSell-10,898808,966$4,942,782
Q1 2023Renaissance Technologies LLCSell-1,325,4001,875,500$11,459
Q4 2022ARK InvestSell-1,497,353819,864$5,238,931
Q4 2022Renaissance Technologies LLCBuy2,392,3003,200,900$20,454
Q3 2022ARK InvestSell-618,4622,317,217$22,199
Q3 2022Renaissance Technologies LLCBuy538,600808,600$7,746
Q2 2022ARK InvestSell-101,7642,935,679$19,816
Q1 2022ARK InvestSell-4,164,0753,037,443$50,573
Q4 2021ARK InvestSell-4,448,3197,201,518$137,477
Q4 2021Renaissance Technologies LLCBuy129,400270,000$5,154
Q3 2021ARK InvestSell-6,800,87611,649,837$287,285
Q2 2021ARK InvestSell-1,275,93718,450,713$480,088
Q1 2021ARK InvestBuy4,428,82819,726,650$624,546
Q1 2021Renaissance Technologies LLCBuy79,200140,600$4,451
Q4 2020ARK InvestBuy7,394,51415,297,822$709,819
Q3 2020ARK InvestBuy3,668,0357,903,308$260,177
Q2 2020ARK InvestBuy3,348,0944,235,273$116,258
Q1 2020ARK InvestBuy63,835887,179$26,558
Q4 2019ARK InvestBuy8,548823,344$22,790
Q3 2019ARK InvestBuy7,108814,796$14,829
Q3 2019Renaissance Technologies LLCBuy61,40061,400$1,117
Q2 2019ARK InvestBuy116,194807,688$19,805
Q1 2019ARK InvestSell-34,866691,494$6,576
Q4 2018ARK InvestBuy301,540726,360$6,428

Frequently asked questions about IOVA activity

  • Which institutional owners are buying IOVA?

    Institutional owners buying IOVA include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in IOVA activity?

    "Buy" means an investor increased their reported position in IOVA compared to the prior reporting period. This reflects growing exposure to IOVANCE BIOTHERAPEUTICS INC (IOVA) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in IOVA increasing?

    Institutional interest in IOVA can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.