PRIME MEDICINE INC (PRME) Institutional Ownership Changes & 13F Activity
PRIME MEDICINE INC (PRME). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Goldman Sachs Group Inc, ARK Invest, Citadel Advisors Llc, Farallon Capital Management Llc, and D. E. Shaw & Co., Inc..
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | Sell | -1,519 | -5.3% | 27,353 | $100.93K | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Buy | +1,718,185 | +510.8% | 2,054,543 | $7.58M | Q2 2026 | Sep 02, 2026 |
| Corient Private Wealth Llc | Sell | -2,143 | -5.2% | 39,078 | $144.20K | Q2 2026 | Aug 27, 2026 |
| California State Teachers Retirement System | Buy | +70,576 | +81.6% | 157,049 | $579.51K | Q2 2026 | Aug 24, 2026 |
| Kingsview Wealth Management, Llc | Sell | -25,000 | -71.4% | 10,000 | $36.90K | Q2 2026 | Aug 19, 2026 |
| Goldman Sachs Group Inc | Buy | +2,460,093 | +253.5% | 3,430,518 | $12.66M | Q2 2026 | Aug 14, 2026 |
| ARK Invest | Buy | +2,101,919 | +33.6% | 8,348,746 | $30.81M | Q2 2026 | Aug 14, 2026 |
| Farallon Capital Management Llc | Buy | +1,240,843 | — | 1,240,843 | $4.58M | Q2 2026 | Aug 14, 2026 |
| D. E. Shaw & Co., Inc. | Sell | -744,681 | -53.4% | 648,940 | $2.39M | Q2 2026 | Aug 14, 2026 |
| Point72 Asset Management, L.P. | Buy | +533,553 | — | 533,553 | $1.97M | Q2 2026 | Aug 14, 2026 |
| Hrt Financial Lp | Sell | -451,259 | -73.6% | 161,510 | $595.00K | Q2 2026 | Aug 14, 2026 |
| Aqr Capital Management Llc | Sell | -436,937 | -78.7% | 117,998 | $435.41K | Q2 2026 | Aug 14, 2026 |
| Millennium Management Llc | Buy | +427,097 | — | 427,097 | $1.58M | Q2 2026 | Aug 14, 2026 |
| Bank Of America Corp | Buy | +404,331 | +70.1% | 981,335 | $3.62M | Q2 2026 | Aug 14, 2026 |
| T. Rowe Price Investment Management, Inc. | Sell | -244,561 | -4.5% | 5,237,332 | $19.33M | Q2 2026 | Aug 14, 2026 |
| Jain Global Llc | Buy | +215,218 | — | 215,218 | $794.15K | Q2 2026 | Aug 14, 2026 |
| Redmile Group, Llc | Sell | -201,200 | -12.6% | 1,389,632 | $5.13M | Q2 2026 | Aug 14, 2026 |
| Balyasny Asset Management L.P. | Sell | -154,283 | -3.7% | 3,969,082 | $14.65M | Q2 2026 | Aug 14, 2026 |
| Invesco Ltd. | Buy | +140,308 | — | 140,308 | $517.74K | Q2 2026 | Aug 14, 2026 |
| Exoduspoint Capital Management, Lp | Buy | +118,464 | — | 118,464 | $437.13K | Q2 2026 | Aug 14, 2026 |
| Rafferty Asset Management, Llc | Sell | -70,307 | -32.6% | 145,275 | $536.07K | Q2 2026 | Aug 14, 2026 |
| Bridgeway Capital Management, Llc | Sell | -70,000 | -51.9% | 64,800 | $239.11K | Q2 2026 | Aug 14, 2026 |
| Wells Fargo & Company/Mn | Sell | -67,803 | -21.2% | 251,747 | $928.95K | Q2 2026 | Aug 14, 2026 |
| Susquehanna International Group, Llp | Sell | -67,350 | -9.4% | 648,479 | $2.39M | Q2 2026 | Aug 14, 2026 |
| Xtx Topco Ltd | Buy | +58,426 | +37.1% | 215,708 | $795.96K | Q2 2026 | Aug 14, 2026 |
| Engineers Gate Manager Lp | Sell | -51,215 | -46.4% | 59,133 | $218.20K | Q2 2026 | Aug 14, 2026 |
| Ameriprise Financial Inc | Buy | +49,941 | — | 49,941 | $184.28K | Q2 2026 | Aug 14, 2026 |
| Two Sigma Investments, Lp | Sell | -48,300 | -3.1% | 1,524,511 | $5.63M | Q2 2026 | Aug 14, 2026 |
| Mirae Asset Global Etfs Holdings Ltd. | Buy | +39,875 | +32.6% | 162,338 | $599.53K | Q2 2026 | Aug 14, 2026 |
| Price T Rowe Associates Inc | Buy | +28,570 | +21.4% | 162,325 | $599.00K | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about PRME activity
Which institutional owners are buying PRME?
Institutional owners buying PRME include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in PRME activity?
"Buy" means an investor increased their reported position in PRME compared to the prior reporting period. This reflects growing exposure to PRIME MEDICINE INC (PRME) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in PRME increasing?
Institutional interest in PRME can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related PRME Institutional Insights
- PRME Overview
- PRME 13F Institutional Holders
- PRME Top Institutional Shareholders
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- PRME Insider Trading & SEC Form 4 Activity
- PRME Articles
- Top Institutional Investor Stock Rankings