PRIME MEDICINE INC (PRME) Institutional Ownership Changes & 13F Activity

PRIME MEDICINE INC (PRME). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings. This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include ARK Invest, Renaissance Technologies LLC, and Sequoia Financial Advisors.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q1 2026ARK InvestBuy878,3016,246,827$21,738,957
Q1 2026Renaissance Technologies LLCSell-408,120741,039$2,578,816
Q1 2026Sequoia Financial AdvisorsBuy11,67311,673$40,623
Q4 2025ARK InvestSell-109,3255,368,526$18,628,784
Q4 2025Renaissance Technologies LLCBuy14,4891,149,159$3,987,582
Q3 2025ARK InvestBuy3,155,1825,477,851$30,347,295
Q3 2025Renaissance Technologies LLCBuy911,2701,134,670$6,286,072
Q2 2025ARK InvestSell-772,5032,322,669$5,736,992
Q2 2025Renaissance Technologies LLCSell-224,200223,400$551,798
Q1 2025ARK InvestSell-2,055,0613,095,172$6,159,392
Q1 2025Renaissance Technologies LLCBuy427,600447,600$890,724
Q4 2024ARK InvestSell-510,4865,150,233$15,038,681
Q3 2024ARK InvestSell-466,0545,660,719$21,906,982
Q3 2024Renaissance Technologies LLCSell-342,40020,000$77,400
Q2 2024ARK InvestBuy133,4196,126,773$31,491,613
Q1 2024ARK InvestBuy2,855,0845,993,354$41,953,475
Q1 2024Renaissance Technologies LLCBuy309,108362,400$2,537
Q4 2023ARK InvestBuy515,8413,138,270$27,805,073
Q4 2023Renaissance Technologies LLCBuy53,29253,292$472
Q3 2023ARK InvestBuy173,2302,622,429$25,017,977
Q2 2023ARK InvestBuy526,9222,449,199$35,880,771
Q1 2023ARK InvestBuy282,2931,922,277$23,644,007
Q4 2022ARK InvestBuy1,639,9841,639,984$30,470,903

Frequently asked questions about PRME activity

  • Which institutional owners are buying PRME?

    Institutional owners buying PRME include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in PRME activity?

    "Buy" means an investor increased their reported position in PRME compared to the prior reporting period. This reflects growing exposure to PRIME MEDICINE INC (PRME) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in PRME increasing?

    Institutional interest in PRME can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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