XENON PHARMACEUTICALS INC (XENE) Institutional Ownership Changes & 13F Activity

XENON PHARMACEUTICALS INC (XENE) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q1 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q1 2026Renaissance Technologies LLCBuy295,300300,500$17,474,075
Q3 2025Renaissance Technologies LLCSell-3,4005,200$208,780
Q2 2025Renaissance Technologies LLCSell-146,1008,600$269,180
Q1 2025Renaissance Technologies LLCBuy141,000154,700$5,190,185
Q4 2024Renaissance Technologies LLCSell-30,30013,700$537,040
Q3 2024Renaissance Technologies LLCSell-48,90044,000$1,732,280
Q2 2024Renaissance Technologies LLCBuy36,50092,900$3,622,171
Q1 2024Renaissance Technologies LLCBuy23,80056,400$2,428
Q4 2023Renaissance Technologies LLCBuy10,70032,600$1,502
Q3 2023Renaissance Technologies LLCSell-128,87721,900$748
Q1 2022Renaissance Technologies LLCSell-230,100150,777$4,609
Q4 2021Renaissance Technologies LLCSell-238,200380,877$11,899
Q3 2021Renaissance Technologies LLCSell-38,900619,077$9,459
Q2 2021Renaissance Technologies LLCSell-35,000657,977$12,252
Q1 2021Renaissance Technologies LLCSell-77,000692,977$12,404
Q4 2020Renaissance Technologies LLCSell-133,300769,977$11,842
Q3 2020Renaissance Technologies LLCSell-132,000903,277$9,999
Q2 2020Renaissance Technologies LLCBuy247,2001,035,277$12,982
Q1 2020Renaissance Technologies LLCBuy192,400788,077$8,937
Q4 2019Renaissance Technologies LLCBuy107,077595,677$7,809
Q3 2019Renaissance Technologies LLCBuy13,100488,600$4,402
Q2 2019Renaissance Technologies LLCBuy3,200475,500$4,688
Q1 2019Renaissance Technologies LLCSell-93,400472,300$4,799
Q4 2018Renaissance Technologies LLCBuy38,363565,700$3,570
Q3 2018Renaissance Technologies LLCBuy239,337527,337$6,961
Q1 2018Renaissance Technologies LLCBuy39,000288,000$1,411
Q4 2017Renaissance Technologies LLCBuy92,600249,000$703
Q3 2017Renaissance Technologies LLCBuy26,100156,400$461
Q2 2017Renaissance Technologies LLCSell-86,790130,300$410
Q1 2017Renaissance Technologies LLCBuy102,890217,090$868

Frequently asked questions about XENE activity

  • Which institutional owners are buying XENE?

    Institutional owners buying XENE include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in XENE activity?

    "Buy" means an investor increased their reported position in XENE compared to the prior reporting period. This reflects growing exposure to XENON PHARMACEUTICALS INC (XENE) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in XENE increasing?

    Institutional interest in XENE can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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