XERIS BIOPHARMA HOLDINGS INC (XERS) Stock Institutional Trading Activity


XERIS BIOPHARMA HOLDINGS INC (XERS) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC, Polen Capital Management, and Fairfax Financial Holdings. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Polen Capital ManagementBuy225133,416$1,047,316
Q4 2025Renaissance Technologies LLCSell-1,003,180619,660$4,864,330
Q3 2025Polen Capital ManagementBuy197133,191$1,084,175
Q3 2025Renaissance Technologies LLCSell-432,5001,622,840$13,209,919
Q2 2025Polen Capital ManagementBuy132,994132,994$621,082
Q2 2025Renaissance Technologies LLCSell-107,3002,055,340$9,598,439
Q1 2025Renaissance Technologies LLCBuy63,8002,162,640$11,872,894
Q4 2024Fairfax Financial HoldingsSell-31,250139,687$472,142
Q4 2024Renaissance Technologies LLCBuy500,1202,098,840$7,115,067
Q3 2024Renaissance Technologies LLCBuy247,0801,598,720$4,556,353
Q2 2024Fairfax Financial HoldingsBuy19,542170,937$382,899
Q2 2024Renaissance Technologies LLCBuy342,3001,351,640$3,041,192
Q1 2024Renaissance Technologies LLCSell-372,3001,009,340$2,231
Q4 2023Renaissance Technologies LLCBuy359,6001,381,640$3,247
Q3 2023Renaissance Technologies LLCBuy163,3461,022,040$1,901
Q2 2023Renaissance Technologies LLCBuy254,800858,694$2,250
Q1 2023Renaissance Technologies LLCBuy105,400603,894$984
Q4 2022Renaissance Technologies LLCSell-51,200498,494$663
Q3 2022Renaissance Technologies LLCSell-94,000549,694$858
Q2 2022Renaissance Technologies LLCSell-49,300643,694$991
Q1 2022Renaissance Technologies LLCSell-187,200692,994$1,774
Q4 2021Fairfax Financial HoldingsBuy151,395151,395$441
Q4 2021Renaissance Technologies LLCBuy880,194880,194$2,579

Frequently asked questions about XERS activity

  • Which institutional owners are buying XERS?

    Institutional owners buying XERS include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in XERS activity?

    "Buy" means an investor increased their reported position in XERS compared to the prior reporting period. This reflects growing exposure to XERIS BIOPHARMA HOLDINGS INC (XERS) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in XERS increasing?

    Institutional interest in XERS can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.