XERIS BIOPHARMA HOLDINGS INC (XERS) Top Institutional Shareholders
XERIS BIOPHARMA HOLDINGS INC (XERS) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $530.99M in XERS holdings during the latest filing period.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of XERS tracked by InsiderSet, reporting ownership valued at approximately $75.09M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $89.33M, representing an estimated gain of +18.97% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 51% of the total disclosed XERS value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., D. E. Shaw & Co., Inc., State Street Corp, and several other long-term asset managers with concentrated positions in XERIS BIOPHARMA HOLDINGS INC (XERS).
This page ranks the largest institutional XERS shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
225
Total Reported Value
$530.99M
Largest Holder
Blackrock, Inc.
Largest Position
$75.09M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
146
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.00% | 12,945,785 | $75,085,553 | $89,325,917 | +$14,240,364 | +18.97% | |
| D. E. Shaw & Co., Inc. | 0.04% | 7,788,811 | $45,175,104 | $53,742,796 | +$8,567,692 | +18.97% | |
| State Street Corp | 0.00% | 4,658,174 | $27,017,409 | $32,141,401 | +$5,123,992 | +18.97% | |
| Geode Capital Management, Llc | 0.00% | 4,290,629 | $24,890,245 | $29,605,340 | +$4,715,095 | +18.94% | |
| Qube Research & Technologies Ltd | 0.03% | 4,114,425 | $23,863,665 | $28,389,533 | +$4,525,868 | +18.97% | |
| Rosalind Advisors, Inc. | 7.68% | 3,231,700 | $18,743,860 | $22,298,730 | +$3,554,870 | +18.97% | |
| Nuveen, Llc | 0.00% | 2,916,598 | $16,916,268 | $20,124,526 | +$3,208,258 | +18.97% | |
| Morgan Stanley | 0.00% | 2,572,654 | $14,921,395 | $17,751,313 | +$2,829,918 | +18.97% | |
| Millennium Management Llc | 0.01% | 2,265,974 | $13,142,649 | $15,635,221 | +$2,492,572 | +18.97% | |
| Wellington Management Group Llp | 0.00% | 2,171,354 | $12,593,854 | $14,982,343 | +$2,388,489 | +18.97% | |
| Two Sigma Investments, Lp | 0.01% | 1,924,202 | $11,160,372 | $13,276,994 | +$2,116,622 | +18.97% | |
| Armistice Capital, Llc | 0.37% | 1,909,838 | $11,077,060 | $13,177,882 | +$2,100,822 | +18.97% | |
| Legal & General Group Plc | 0.00% | 1,908,289 | $11,068,077 | $13,167,194 | +$2,099,117 | +18.97% | |
| Parkman Healthcare Partners Llc | 1.04% | 1,721,264 | $9,983,331 | $11,876,722 | +$1,893,391 | +18.97% | |
| Ubs Group Ag | 0.00% | 1,646,378 | $9,548,993 | $11,360,008 | +$1,811,015 | +18.97% | |
| Goldman Sachs Group Inc | 0.00% | 1,613,650 | $9,359,170 | $11,134,185 | +$1,775,015 | +18.97% | |
| Northern Trust Corp | 0.00% | 1,444,617 | $8,378,778 | $9,967,857 | +$1,589,079 | +18.97% | |
| Aqr Capital Management Llc | 0.00% | 1,394,376 | $8,087,382 | $9,621,194 | +$1,533,812 | +18.97% | |
| Voss Capital, Lp | 0.46% | 1,386,927 | $8,044,177 | $9,569,796 | +$1,525,619 | +18.97% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,359,657 | $7,886,011 | $9,381,633 | +$1,495,622 | +18.97% | |
| Centerbook Partners Lp | 0.39% | 1,248,621 | $7,242,002 | $8,615,485 | +$1,373,483 | +18.97% | |
| Kennedy Capital Management Llc | 0.15% | 1,240,692 | $7,196,014 | $8,560,775 | +$1,364,761 | +18.97% | |
| Knott David M Jr | 3.66% | 1,060,000 | $6,148,000 | $7,314,000 | +$1,166,000 | +18.97% | |
| Ishara Investments Lp | 6.00% | 1,025,000 | $5,945,000 | $7,072,500 | +$1,127,500 | +18.97% | |
| Granahan Investment Management, Llc | 0.26% | 921,854 | $5,346,753 | $6,360,793 | +$1,014,040 | +18.97% | |
| Driehaus Capital Management Llc | 0.04% | 902,740 | $5,235,892 | $6,228,906 | +$993,014 | +18.97% | |
| Bank Of America Corp | 0.00% | 874,397 | $5,071,502 | $6,033,339 | +$961,837 | +18.97% | |
| Federated Hermes, Inc. | 0.01% | 856,813 | $4,969,515 | $5,912,010 | +$942,495 | +18.97% | |
| Trexquant Investment Lp | 0.03% | 833,217 | $4,832,659 | $5,749,197 | +$916,538 | +18.97% | |
| Essex Investment Management Co Llc | 0.69% | 747,769 | $4,337,060 | $5,159,606 | +$822,546 | +18.97% | |
| Jane Street Group, Llc | 0.00% | 725,616 | $4,208,573 | $5,006,750 | +$798,177 | +18.97% | |
| Citadel Advisors Llc | 0.00% | 681,634 | $3,953,477 | $4,703,275 | +$749,798 | +18.97% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.00% | 668,074 | $3,874,829 | $4,609,711 | +$734,882 | +18.97% | |
| Voya Investment Management Llc | 0.00% | 625,310 | $3,626,798 | $4,314,639 | +$687,841 | +18.97% | |
| Deutsche Bank Ag\ | 0.00% | 623,012 | $3,613,470 | $4,298,783 | +$685,313 | +18.97% | |
| Squarepoint Ops Llc | 0.01% | 614,550 | $3,564,390 | $4,240,395 | +$676,005 | +18.97% | |
| Sei Investments Co | 0.00% | 579,210 | $3,359,432 | $3,996,549 | +$637,117 | +18.97% | |
| Fmr Llc | 0.00% | 513,076 | $2,975,841 | $3,540,224 | +$564,383 | +18.97% | |
| Healthcare Of Ontario Pension Plan Trust Fund | 0.00% | 464,084 | $2,691,687 | $3,202,180 | +$510,493 | +18.97% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 452,860 | $2,626,589 | $3,124,734 | +$498,145 | +18.97% |
| Bank Of New York Mellon Corp | 0.00% | 426,285 | $2,472,453 | $2,941,367 | +$468,914 | +18.97% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | 407,625 | $2,364,225 | $2,812,613 | +$448,388 | +18.97% | |
| Russell Investments Group, Ltd. | 0.00% | 384,195 | $2,228,331 | $2,650,946 | +$422,615 | +18.97% | |
| Iht Wealth Management, Llc | 0.05% | 376,476 | $2,183,561 | $2,597,684 | +$414,123 | +18.97% | |
| Canada Pension Plan Investment Board | 0.00% | 374,800 | $2,173,840 | $2,586,120 | +$412,280 | +18.97% | |
| Voloridge Investment Management, Llc | 0.01% | 370,116 | $2,146,673 | $2,553,800 | +$407,127 | +18.97% | |
| Swiss National Bank | 0.00% | 328,300 | $1,904,140 | $2,265,270 | +$361,130 | +18.97% | |
| State Of Wisconsin Investment Board | 0.00% | 308,546 | $1,789,567 | $2,128,967 | +$339,400 | +18.97% | |
| Schonfeld Strategic Advisors Llc | 0.01% | 296,431 | $1,719,299 | $2,045,374 | +$326,075 | +18.97% | |
| Janus Henderson Group Plc | 0.00% | 295,489 | $1,713,487 | $2,038,874 | +$325,387 | +18.99% |
Frequently asked questions about XERS
Who owns the most XERS stock?
The largest holders of XERS are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for XERIS BIOPHARMA HOLDINGS INC (XERS).
Is XERS widely held by superinvestors?
Many widely followed stocks like XERS appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly XERS is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.