Perceptive Advisors Llc Portfolio Stock Holdings
According to the SEC 13F filed on August 14, 2026, Perceptive Advisors Llc disclosed 84 stock positions valued at approximately $6.44B as of quarter-end June 30, 2026. The largest holdings include PRAXIS PRECISION MEDICINES I, SPYRE THERAPEUTICS INC, and CELCUITY INC.
- Report Period
- June 30, 2026
- No. of Stocks
- 84
- Portfolio Value
- $6.44B
Holdings by Sector
Perceptive Advisors Llc Portfolio Holdings in Q2 2026
| Company | Symbol | Sector | Portfolio % | Shares | Change (Shares) | Change % | Value |
|---|---|---|---|---|---|---|---|
| PRAXIS PRECISION MEDICINES I | PRAX | Healthcare | 10.58% | 2,035,986 | - | - | $681,627,753 |
| SPYRE THERAPEUTICS INC | SYRE | Healthcare | 5.95% | 4,319,496 | +536,271 | +14.17% | $383,484,855 |
| CELCUITY INC | CELC | Healthcare | 5.19% | 3,197,200 | +70,000 | +2.24% | $334,491,064 |
| RHYTHM PHARMACEUTICALS INC | RYTM | Healthcare | 4.46% | 2,586,295 | +212,500 | +8.95% | $287,156,334 |
| ROIVANT SCIENCES LTD | ROIV | Healthcare | 4.44% | 8,085,461 | -200,000 | -2.41% | $286,144,465 |
| RELAY THERAPEUTICS INC | RLAY | Healthcare | 4.10% | 14,106,187 | +4,355,046 | +44.66% | $263,926,759 |
| TRAVERE THERAPEUTICS INC | TVTX | Healthcare | 3.31% | 3,752,574 | -389,977 | -9.41% | $213,183,729 |
| NUVALENT INC | NUVL | Healthcare | 3.03% | 1,580,505 | - | - | $195,192,368 |
| EDGEWISE THERAPEUTICS INC | EWTX | Healthcare | 2.76% | 4,373,974 | -50,000 | -1.13% | $177,714,564 |
| APOGEE THERAPEUTICS INC | APGE | Healthcare | 2.70% | 1,308,113 | -232,271 | -15.08% | $173,625,838 |
| AMYLYX PHARMACEUTICALS INC | AMLX | Healthcare | 2.32% | 8,334,882 | +50,000 | +0.60% | $149,694,481 |
| MEIRAGTX HLDGS PLC | MGTX | Other | 2.26% | 10,786,658 | +460,555 | +4.46% | $145,727,749 |
| INHIBRX BIOSCIENCES INC | INBX | Healthcare | 1.91% | 1,297,763 | -144,944 | -10.05% | $122,963,044 |
| PROTAGONIST THERAPEUTICS INC | PTGX | Healthcare | 1.87% | 981,879 | -249,000 | -20.23% | $120,358,728 |
| SOLID BIOSCIENCES INC | SLDB | Healthcare | 1.85% | 11,906,646 | - | - | $118,947,393 |
| ZYMEWORKS INC | ZYME | Healthcare | 1.70% | 4,182,953 | +672,875 | +19.17% | $109,342,391 |
| TANGO THERAPEUTICS INC | TNGX | Healthcare | 1.64% | 3,377,000 | +2,568,847 | +317.87% | $105,565,020 |
| IMMATICS N.V | IMTX | Other | 1.63% | 10,383,456 | - | - | $105,184,409 |
| NURIX THERAPEUTICS INC | NRIX | Healthcare | 1.63% | 4,320,422 | +609,545 | +16.43% | $104,813,438 |
| BIOCRYST PHARMACEUTICALS INC | BCRX | Healthcare | 1.60% | 10,308,888 | +2,874,855 | +38.67% | $103,088,880 |
| REVOLUTION MEDICINES INC | RVMD | Healthcare | 1.53% | 527,600 | +269,000 | +104.02% | $98,808,928 |
| AVALYN PHARMACEUTICALS INC | AVLN | Other | 1.37% | 2,675,296 | +2,675,296 | +100.00% | $88,070,744 |
| DYNE THERAPEUTICS INC | DYN | Healthcare | 0.93% | 2,689,235 | -1,979,604 | -42.40% | $59,727,909 |
| BIOGEN INC | BIIB | Healthcare | 0.93% | 276,173 | +152,173 | +122.72% | $59,669,938 |
| IMMUNOVANT INC | IMVT | Healthcare | 0.81% | 1,357,383 | -240,000 | -15.02% | $52,299,967 |
| UNITEDHEALTH GROUP INC | UNH | Healthcare | 0.75% | 116,806 | +116,806 | +100.00% | $48,548,078 |
| IONIS PHARMACEUTICALS INC | IONS | Healthcare | 0.70% | 566,000 | +62,000 | +12.30% | $44,878,140 |
| ALTO NEUROSCIENCE INC | ANRO | Healthcare | 0.66% | 1,609,893 | -400,000 | -19.90% | $42,485,076 |
| JAZZ PHARMACEUTICALS PLC | JAZZ | Other | 0.64% | 170,000 | - | - | $40,964,900 |
| CORVUS PHARMACEUTICALS INC | CRVS | Healthcare | 0.62% | 2,667,441 | +375,000 | +16.36% | $39,851,569 |
Showing 30 of 84 holdings in the latest reporting period.
Perceptive Advisors Llc Options Holdings in Q2 2026
| Quarter | Symbol | Company | Option | Contracts | Notional Value |
|---|---|---|---|---|---|
| Q2 2026 | MRNA | Moderna, Inc. | PUT | 1,000,000 | $70,030,000 |
| Q2 2026 | XBI | SPDR Series Trust SPDR S&P Bio | PUT | 300,000 | $47,475,000 |
| Q2 2026 | EYPT | EyePoint Pharmaceuticals, Inc. | PUT | 2,000,000 | $28,600,000 |
| Q2 2026 | CAPR | Capricor Therapeutics, Inc. | CALL | 1,000,000 | $24,080,000 |
| Q2 2026 | SLS | SELLAS Life Sciences Group, Inc | PUT | 1,500,000 | $22,140,000 |
| Q2 2026 | NAMSW | NewAmsterdam Pharma | PUT | 500,000 | $16,945,000 |
| Q2 2026 | CAPR | Capricor Therapeutics, Inc. | PUT | 500,000 | $12,040,000 |
Showing 7 of 7 options positions in the latest reporting period.
Notional value represents the total exposure of the options position.