PRAXIS PRECISION MEDICINES I (PRAX) Institutional Shareholders
PRAXIS PRECISION MEDICINES I (PRAX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $10.05B in PRAX holdings during the latest filing period.
Fmr Llc is currently the largest disclosed institutional shareholder of PRAX tracked by InsiderSet, reporting ownership valued at approximately $775.68M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $715.90M, representing an estimated loss of -7.71% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 52% of the total disclosed PRAX value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Perceptive Advisors Llc, and several other long-term asset managers with concentrated positions in PRAXIS PRECISION MEDICINES I (PRAX).
This page ranks the largest institutional PRAX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
296
Total Reported Value
$10.05B
Largest Holder
Fmr Llc
Largest Position
$775.68M
Insider Transactions (90d)
16
Latest Filing Quarter
Q2 2026
New Institutional Positions
64
Funds Exiting Positions
2
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.03% | 2,316,907 | $775,677,279 | $715,901,094 | -$59,776,185 | -7.71% | |
| Blackrock, Inc. | 0.01% | 2,292,585 | $767,534,532 | $708,385,839 | -$59,148,693 | -7.71% | |
| Perceptive Advisors Llc | 10.58% | 2,035,986 | $681,627,753 | $629,099,314 | -$52,528,439 | -7.71% | |
| Baker Bros. Advisors Lp | 2.94% | 1,753,198 | $586,953,158 | $541,720,650 | -$45,232,508 | -7.71% | |
| Orbis Allan Gray Ltd | 1.76% | 1,529,788 | $512,157,724 | $472,689,194 | -$39,468,530 | -7.71% | |
| Vanguard Portfolio Management Llc | 0.02% | 1,335,185 | $447,006,586 | $412,558,813 | -$34,447,773 | -7.71% | |
| Vanguard Capital Management Llc | 0.01% | 1,235,299 | $413,565,752 | $381,695,038 | -$31,870,714 | -7.71% | |
| State Street Corp | 0.01% | 1,026,443 | $343,656,004 | $317,160,623 | -$26,495,381 | -7.71% | |
| Adage Capital Partners Gp, L.L.C. | 0.48% | 1,015,480 | $339,972,549 | $313,773,165 | -$26,199,384 | -7.71% | |
| Deerfield Management Company, L.P. | 3.36% | 963,351 | $322,520,281 | $297,665,825 | -$24,854,456 | -7.71% | |
| Driehaus Capital Management Llc | 1.86% | 959,048 | $321,079,680 | $296,336,242 | -$24,743,438 | -7.71% | |
| Price T Rowe Associates Inc | 0.03% | 942,999 | $315,707,000 | $291,377,261 | -$24,329,739 | -7.71% | |
| Morgan Stanley | 0.02% | 854,112 | $285,948,294 | $263,912,067 | -$22,036,227 | -7.71% | |
| Geode Capital Management, Llc | 0.01% | 748,039 | $250,477,901 | $231,136,571 | -$19,341,330 | -7.72% | |
| Cormorant Asset Management, Lp | 10.98% | 640,000 | $214,265,600 | $197,753,600 | -$16,512,000 | -7.71% | |
| Goldman Sachs Group Inc | 0.02% | 548,830 | $183,742,796 | $169,582,982 | -$14,159,814 | -7.71% | |
| Bank Of America Corp | 0.01% | 546,930 | $183,106,695 | $168,995,901 | -$14,110,794 | -7.71% | |
| Invesco Ltd. | 0.01% | 537,548 | $179,965,694 | $166,096,957 | -$13,868,737 | -7.71% | |
| Hood River Capital Management Llc | 1.03% | 425,167 | $142,341,660 | $131,372,351 | -$10,969,309 | -7.71% | |
| Norges Bank | 0.01% | 346,969 | $116,161,752 | $107,209,951 | -$8,951,801 | -7.71% | |
| Pictet Asset Management Holding Sa | 0.09% | 291,689 | $98,035,469 | $90,128,984 | -$7,906,485 | -8.06% | |
| Polar Capital Holdings Plc | 0.26% | 279,131 | $93,450,267 | $86,248,688 | -$7,201,579 | -7.71% | |
| Vivo Capital, Llc | 8.29% | 271,116 | $90,766,926 | $83,772,133 | -$6,994,793 | -7.71% | |
| Logos Global Management Lp | 3.75% | 260,000 | $87,045,400 | $80,337,400 | -$6,708,000 | -7.71% | |
| Northern Trust Corp | 0.01% | 240,887 | $80,646,559 | $74,431,674 | -$6,214,885 | -7.71% | |
| American Century Companies Inc | 0.04% | 237,315 | $79,451,539 | $73,327,962 | -$6,123,577 | -7.71% | |
| Orbimed Advisors Llc | 1.46% | 230,100 | $77,035,179 | $71,098,599 | -$5,936,580 | -7.71% | |
| Charles Schwab Investment Management Inc | 0.01% | 220,008 | $73,656,478 | $67,980,272 | -$5,676,206 | -7.71% | |
| Westfield Capital Management Co Lp | 0.24% | 218,898 | $73,284,861 | $67,637,293 | -$5,647,568 | -7.71% | |
| Woodline Partners Lp | 0.21% | 200,013 | $66,962,352 | $61,802,017 | -$5,160,335 | -7.71% | |
| Bnp Paribas Financial Markets | 0.03% | 188,409 | $63,077,449 | $58,216,497 | -$4,860,952 | -7.71% | |
| Vanguard Fiduciary Trust Co | 0.01% | 188,161 | $62,994,421 | $58,139,867 | -$4,854,554 | -7.71% | |
| Affinity Asset Advisors, Llc | 3.03% | 185,000 | $61,936,150 | $57,163,150 | -$4,773,000 | -7.71% | |
| Soleus Capital Management, L.P. | 2.05% | 177,517 | $59,430,916 | $54,850,978 | -$4,579,938 | -7.71% | |
| Aberdeen Group Plc | 0.08% | 166,399 | $55,708,721 | $51,415,627 | -$4,293,094 | -7.71% | |
| T. Rowe Price Investment Management, Inc. | 0.04% | 160,477 | $53,727,000 | $49,585,788 | -$4,141,212 | -7.71% | |
| Qube Research & Technologies Ltd | 0.06% | 152,475 | $51,047,105 | $47,113,250 | -$3,933,855 | -7.71% | |
| Marshall Wace, Llp | 0.04% | 137,008 | $45,868,907 | $42,334,102 | -$3,534,805 | -7.71% | |
| Ubs Group Ag | 0.01% | 131,046 | $43,872,891 | $40,491,904 | -$3,380,987 | -7.71% | |
| Wellington Management Group Llp | 0.01% | 125,867 | $42,139,013 | $38,891,644 | -$3,247,369 | -7.71% | |
| Voya Investment Management Llc | 0.04% | 122,227 | $40,920,377 | $37,766,921 | -$3,153,456 | -7.71% | |
| Nuveen, Llc | 0.01% | 108,032 | $36,168,033 | $33,380,808 | -$2,787,225 | -7.71% | |
| Massachusetts Financial Services Co | 0.01% | 107,409 | $35,959,459 | $33,188,307 | -$2,771,152 | -7.71% | |
| Metlife Investment Management, Llc | 0.14% | 90,543 | $30,312,891 | $27,976,882 | -$2,336,009 | -7.71% | |
| Neuberger Berman Group Llc | 0.02% | 89,468 | $29,952,992 | $27,644,717 | -$2,308,275 | -7.71% | |
| Velan Capital Investment Management Lp | 18.21% | 88,781 | $29,722,991 | $27,432,441 | -$2,290,550 | -7.71% | |
| Bank Of New York Mellon Corp | 0.00% | 85,376 | $28,583,031 | $26,380,330 | -$2,202,701 | -7.71% | |
| First Turn Management, Llc | 2.99% | 83,528 | $27,964,339 | $25,809,317 | -$2,155,022 | -7.71% | |
| Acuta Capital Partners, Llc | 19.32% | 82,796 | $27,719,273 | $25,583,136 | -$2,136,137 | -7.71% | |
| Janus Henderson Group Plc | 0.01% | 84,947 | $27,358,992 | $26,247,774 | -$1,111,218 | -4.06% |
Frequently asked questions about PRAX
Who owns the most PRAX stock?
The largest holders of PRAX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for PRAXIS PRECISION MEDICINES I (PRAX).
Is PRAX widely held by superinvestors?
Many widely followed stocks like PRAX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly PRAX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.