PRAX Institutional Ownership & Shareholders
PRAXIS PRECISION MEDICINES I (PRAX) is currently held by 318 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $10.05B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Fmr Llc is currently the largest disclosed institutional shareholder of PRAX tracked by InsiderSet, reporting ownership valued at approximately $775.68M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $662.47M, representing an estimated loss of -14.59% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 52% of the total disclosed PRAX value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Perceptive Advisors Llc, and several other long-term asset managers with concentrated positions in PRAXIS PRECISION MEDICINES I (PRAX).
This page ranks the largest institutional PRAX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
318
Total Reported Value
$10.05B
Largest Holder
Fmr Llc
Largest Position
$775.68M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
67
Funds Exiting Positions
1
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.03% | 2,316,907 | $775,677,279 | $662,473,219 | -$113,204,060 | -14.59% | |
| Blackrock, Inc. | 0.01% | 2,292,585 | $767,534,532 | $655,518,829 | -$112,015,703 | -14.59% | |
| Perceptive Advisors Llc | 10.58% | 2,035,986 | $681,627,753 | $582,149,477 | -$99,478,276 | -14.59% | |
| Baker Bros. Advisors Lp | 2.94% | 1,753,198 | $586,953,158 | $501,291,904 | -$85,661,254 | -14.59% | |
| Orbis Allan Gray Ltd | 1.76% | 1,529,788 | $512,157,724 | $437,412,283 | -$74,745,441 | -14.59% | |
| Vanguard Portfolio Management Llc | 0.02% | 1,335,185 | $447,006,586 | $381,769,447 | -$65,237,139 | -14.59% | |
| Vanguard Capital Management Llc | 0.01% | 1,235,299 | $413,565,752 | $353,209,043 | -$60,356,709 | -14.59% | |
| State Street Corp | 0.01% | 1,026,443 | $343,656,004 | $293,490,847 | -$50,165,157 | -14.60% | |
| Adage Capital Partners Gp, L.L.C. | 0.48% | 1,015,480 | $339,972,549 | $290,356,196 | -$49,616,353 | -14.59% | |
| Deerfield Management Company, L.P. | 3.36% | 963,351 | $322,520,281 | $275,450,951 | -$47,069,330 | -14.59% | |
| Driehaus Capital Management Llc | 1.86% | 959,048 | $321,079,680 | $274,220,595 | -$46,859,085 | -14.59% | |
| Price T Rowe Associates Inc | 0.03% | 942,999 | $315,707,000 | $269,631,704 | -$46,075,296 | -14.59% | |
| Morgan Stanley | 0.02% | 854,112 | $285,948,294 | $244,216,244 | -$41,732,050 | -14.59% | |
| Geode Capital Management, Llc | 0.01% | 748,039 | $250,477,901 | $213,886,791 | -$36,591,110 | -14.61% | |
| Cormorant Asset Management, Lp | 10.98% | 640,000 | $214,265,600 | $182,995,200 | -$31,270,400 | -14.59% | |
| Goldman Sachs Group Inc | 0.02% | 548,830 | $183,742,796 | $156,926,962 | -$26,815,834 | -14.59% | |
| Bank Of America Corp | 0.01% | 546,930 | $183,106,695 | $156,383,695 | -$26,723,000 | -14.59% | |
| Invesco Ltd. | 0.01% | 537,548 | $179,965,694 | $153,701,100 | -$26,264,594 | -14.59% | |
| Hood River Capital Management Llc | 1.03% | 425,167 | $142,341,660 | $121,568,000 | -$20,773,660 | -14.59% | |
| Norges Bank | 0.01% | 346,969 | $116,161,752 | $99,208,846 | -$16,952,906 | -14.59% | |
| Pictet Asset Management Holding Sa | 0.09% | 291,689 | $98,035,469 | $83,402,636 | -$14,632,833 | -14.93% | |
| Polar Capital Holdings Plc | 0.26% | 279,131 | $93,450,267 | $79,811,927 | -$13,638,340 | -14.59% | |
| Vivo Capital, Llc | 8.29% | 271,116 | $90,766,926 | $77,520,198 | -$13,246,728 | -14.59% | |
| Logos Global Management Lp | 3.75% | 260,000 | $87,045,400 | $74,341,800 | -$12,703,600 | -14.59% | |
| Northern Trust Corp | 0.01% | 240,887 | $80,646,559 | $68,876,820 | -$11,769,739 | -14.59% | |
| American Century Companies Inc | 0.04% | 237,315 | $79,451,539 | $67,855,478 | -$11,596,061 | -14.60% | |
| Orbimed Advisors Llc | 1.46% | 230,100 | $77,035,179 | $65,792,493 | -$11,242,686 | -14.59% | |
| Charles Schwab Investment Management Inc | 0.01% | 220,008 | $73,656,478 | $62,906,887 | -$10,749,591 | -14.59% | |
| Westfield Capital Management Co Lp | 0.24% | 218,898 | $73,284,861 | $62,589,505 | -$10,695,356 | -14.59% | |
| Woodline Partners Lp | 0.21% | 200,013 | $66,962,352 | $57,189,717 | -$9,772,635 | -14.59% | |
| Bnp Paribas Financial Markets | 0.03% | 188,409 | $63,077,449 | $53,871,785 | -$9,205,664 | -14.59% | |
| Vanguard Fiduciary Trust Co | 0.01% | 188,161 | $62,994,421 | $53,800,875 | -$9,193,546 | -14.59% | |
| Affinity Asset Advisors, Llc | 3.03% | 185,000 | $61,936,150 | $52,897,050 | -$9,039,100 | -14.59% | |
| Soleus Capital Management, L.P. | 2.05% | 177,517 | $59,430,916 | $50,757,436 | -$8,673,480 | -14.59% | |
| Aberdeen Group Plc | 0.08% | 166,399 | $55,708,721 | $47,578,466 | -$8,130,255 | -14.59% | |
| T. Rowe Price Investment Management, Inc. | 0.04% | 160,477 | $53,727,000 | $45,885,189 | -$7,841,811 | -14.60% | |
| Qube Research & Technologies Ltd | 0.06% | 152,475 | $51,047,105 | $43,597,177 | -$7,449,928 | -14.59% | |
| Marshall Wace, Llp | 0.04% | 137,008 | $45,868,907 | $39,174,697 | -$6,694,210 | -14.59% | |
| Ubs Group Ag | 0.01% | 131,046 | $43,872,891 | $37,469,983 | -$6,402,908 | -14.59% | |
| Wellington Management Group Llp | 0.01% | 125,867 | $42,139,013 | $35,989,151 | -$6,149,862 | -14.59% | |
| Voya Investment Management Llc | 0.04% | 122,227 | $40,920,377 | $34,948,366 | -$5,972,011 | -14.59% | |
| Nuveen, Llc | 0.01% | 108,032 | $36,168,033 | $30,889,590 | -$5,278,443 | -14.59% | |
| Massachusetts Financial Services Co | 0.01% | 107,409 | $35,959,459 | $30,711,455 | -$5,248,004 | -14.59% | |
| Metlife Investment Management, Llc | 0.14% | 90,543 | $30,312,891 | $25,888,960 | -$4,423,931 | -14.59% | |
| Velan Capital Investment Management Lp | 18.21% | 88,781 | $29,722,991 | $25,385,151 | -$4,337,840 | -14.59% | |
| Bank Of New York Mellon Corp | 0.00% | 85,376 | $28,583,031 | $24,411,560 | -$4,171,471 | -14.59% | |
| First Turn Management, Llc | 2.99% | 83,528 | $27,964,339 | $23,883,161 | -$4,081,178 | -14.59% | |
| Acuta Capital Partners, Llc | 19.32% | 82,796 | $27,719,273 | $23,673,860 | -$4,045,413 | -14.59% | |
| Janus Henderson Group Plc | 0.01% | 84,947 | $27,358,992 | $24,288,896 | -$3,070,096 | -11.22% | |
| Alyeska Investment Group, L.P. | 0.07% | 80,846 | $27,066,432 | $23,116,297 | -$3,950,135 | -14.59% |
Frequently asked questions about PRAX
Who are the largest institutional holders of PRAX?
The largest institutional holders of PRAX reported in the latest SEC Form 13F filings include Fmr Llc, Blackrock, Inc., Perceptive Advisors Llc, Baker Bros. Advisors Lp, and Orbis Allan Gray Ltd. InsiderSet ranks institutional holders by their latest reported PRAX position.
What is PRAX institutional ownership?
This page tracks PRAX positions reported by institutional investment managers through SEC Form 13F. PRAXIS PRECISION MEDICINES I (PRAX) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own PRAX?
InsiderSet currently tracks 318 institutional managers reporting PRAX holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of PRAX shareholders.
How much PRAX stock do institutions own?
Institutional investment managers disclosed approximately $10.05B in PRAX holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was PRAX institutional ownership last updated?
The latest PRAX institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional PRAX holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its PRAX position after the reporting date.
Are institutions buying or selling PRAX?
Institutional buying and selling can be analyzed by comparing PRAX positions across consecutive 13F reporting periods. InsiderSet's PRAX Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View PRAX ownership changes.
How has PRAX institutional ownership changed over time?
InsiderSet tracks PRAX institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.