Affinity Asset Advisors, Llc Portfolio Stock Holdings

Affinity Asset Advisors, Llc disclosed 95 stock positions valued at approximately $1.7 billion in its latest SEC 13F filing. The largest holdings include APOGEE THERAPEUTICS INC, XENON PHARMACEUTICALS INC, and ERASCA INC. The filing reflects positions held as of March 31, 2026 and was filed on May 14, 2026.

Report Period
March 31, 2026
No. of Stocks
95
Portfolio Value
$1.7B
Holdings by Sector
Affinity Asset Advisors, Llc Portfolio Holdings in Q1 2026

65 holdings in the latest reporting period.

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CompanySymbolSectorPortfolio %SharesChange (Shares)Change %Value
APOGEE THERAPEUTICS INCAPGEHealthcare6.34%1,284,926+50,000+4.05%$108,152,221
XENON PHARMACEUTICALS INCXENEHealthcare5.71%1,675,000+425,000+34.00%$97,401,250
ERASCA INCERASHealthcare5.08%5,350,000+1,450,000+37.18%$86,563,000
INSMED INCINSMHealthcare4.60%480,000+30,000+6.67%$78,489,600
ROIVANT SCIENCES LTDG76279101Other4.55%2,800,000+1,100,000+64.71%$77,560,000
SPYRE THERAPEUTICS INCSYREHealthcare3.78%1,279,134-153,457-10.71%$64,519,519
CENTESSA PHARMACEUTICALS PLCCNTAHealthcare3.26%1,400,000+799,448+133.12%$55,608,000
PRAXIS PRECISION MEDICINES IPRAXHealthcare3.21%170,000-15,000-8.11%$54,772,300
ANAPTYSBIO INCANABHealthcare3.06%940,000+495,308+111.38%$52,132,400
ALKERMES PLCG01767105Other2.80%1,350,000+350,000+35.00%$47,736,000
CYTOKINETICS INCCYTKHealthcare2.71%700,483-99,517-12.44%$46,168,835
ABIVAX SAABVXHealthcare2.64%405,000-100,000-19.80%$45,096,750
TEVA PHARMACEUTICAL INDS LTDTEVAHealthcare2.47%1,400,000--$42,168,000
ARCELLX INCACLXHealthcare2.44%362,764-160,961-30.73%$41,652,562
NUVALENT INCNUVLHealthcare1.80%300,000-22,633-7.02%$30,735,000
TERNS PHARMACEUTICALS INCTERNHealthcare1.74%562,631+12,631+2.30%$29,661,906
DIANTHUS THERAPEUTICS INCDNTHHealthcare1.72%350,000+235,000+204.35%$29,372,000
LEXEO THERAPEUTICS INCLXEOHealthcare1.70%5,050,211+1,850,211+57.82%$28,988,211
COGENT BIOSCIENCES INCCOGTHealthcare1.69%750,000+400,000+114.29%$28,867,500
MADRIGAL PHARMACEUTICALS INCMDGLHealthcare1.69%55,000+23,869+76.67%$28,790,850
TREVI THERAPEUTICS INCTRVIHealthcare1.40%2,000,172-150,000-6.98%$23,862,052
OVID THERAPEUTICS INCOVIDHealthcare1.38%10,636,318+3,486,318+48.76%$23,612,626
ENLIVEN THERAPEUTICS INCELVNHealthcare1.35%586,904+586,904+100.00%$23,006,637
ASCENDIS PHARMA A/SASNDHealthcare1.27%95,000+65,000+216.67%$21,729,350
MINERALYS THERAPEUTICS INCMLYSHealthcare1.19%750,000+20,000+2.74%$20,317,500
AVALO THERAPEUTICS INCAVTXHealthcare1.17%1,340,840+289,786+27.57%$20,018,741
PROTAGONIST THERAPEUTICS INCPTGXHealthcare1.06%172,125--$18,141,975
CELLDEX THERAPEUTICS INC NEWCLDXHealthcare0.93%500,000+150,000+42.86%$15,860,000
NURIX THERAPEUTICS INCNRIXHealthcare0.88%967,620--$14,998,110
SAVARA INCSVRAHealthcare0.80%2,512,153-285,000-10.19%$13,716,355
PERSPECTIVE THERAPEUTICS INCCATXHealthcare0.77%3,164,582+2,864,582+954.86%$13,196,307
ARROWHEAD PHARMACEUTICALS INARWRHealthcare0.74%200,000+130,000+185.71%$12,540,000
ALTO NEUROSCIENCE INCANROHealthcare0.66%500,000+500,000+100.00%$11,240,000
BRIDGEBIO PHARMA INCBBIOHealthcare0.65%150,000-170,000-53.13%$11,139,000
CULLINAN THERAPEUTICS INCCGEMHealthcare0.65%781,260-1,150,846-59.56%$11,101,705
BELITE BIO INCBLTEHealthcare0.61%65,000+45,000+225.00%$10,363,600
VERA THERAPEUTICS INCVERAHealthcare0.59%250,000--$10,057,500
TYRA BIOSCIENCES INCTYRAHealthcare0.58%257,512+257,512+100.00%$9,862,710
REVOLUTION MEDICINES INCRVMDHealthcare0.57%100,000--$9,725,000
TRAVERE THERAPEUTICS INCTVTXHealthcare0.52%300,000--$8,913,000
NEWAMSTERDAM PHARMA COMPANYNAMSWOther0.52%275,000--$8,802,750
KORRO BIO INCKRROHealthcare0.47%706,904+706,904+100.00%$8,002,153
COMPASS PATHWAYS PLCCMPSHealthcare0.36%1,108,483+908,483+454.24%$6,129,911
IBIO INCIBIOHealthcare0.35%3,107,200+1,050,000+51.04%$5,903,680
ESTABLISHMENT LABS HLDGS INCESTAOther0.33%100,000-100,000-50.00%$5,678,000
VIRIDIAN THERAPEUTICS INCVRDNHealthcare0.29%250,000--$4,890,000
CLIMB BIO INCELYMOther0.28%700,000-600,000-46.15%$4,795,000
REZOLUTE INCRZLTHealthcare0.28%1,547,641-803,503-34.17%$4,720,305
SAGIMET BIOSCIENCES INCSGMTHealthcare0.27%868,020-280,225-24.40%$4,535,405
TAYSHA GENE THERAPIES INCTSHAHealthcare0.26%1,000,000-2,300,000-69.70%$4,470,000
ENGENE HOLDINGS INCENGNHealthcare0.24%610,370-33,000-5.13%$4,156,620
ARRIVENT BIOPHARMA INCAVBPHealthcare0.24%175,000+25,000+16.67%$4,037,250
RELAY THERAPEUTICS INCRLAYHealthcare0.23%400,000+400,000+100.00%$3,980,000
PRECISION BIOSCIENCES INCDTILHealthcare0.19%597,946+597,946+100.00%$3,288,703
CRINETICS PHARMACEUTICALS INCRNXHealthcare0.16%75,000--$2,724,000
IMMUNOVANT INCIMVTHealthcare0.15%100,000-100,000-50.00%$2,484,000
EQUILLIUM INCEQHealthcare0.14%1,226,310+1,226,310+100.00%$2,452,620
SAB BIOTHERAPEUTICS INCSABSHealthcare0.13%575,000+575,000+100.00%$2,202,250
CORCEPT THERAPEUTICS INCCORTHealthcare0.12%50,000+50,000+100.00%$2,015,500
ORCHESTRA BIOMED HLDGS INCOBIOHealthcare0.10%402,550-170,254-29.72%$1,710,838
MACROGENICS INCMGNXHealthcare0.08%500,000+15,692+3.24%$1,445,000
ALECTOR INCALECHealthcare0.06%500,000+500,000+100.00%$1,075,000
LENZ THERAPEUTICS INCLENZHealthcare0.05%100,000+100,000+100.00%$915,000
Q32 BIO INCQTTBHealthcare0.01%27,777--$178,328
ROCKET PHARMACEUTICALS INCRCKTWOther0.00%75,000--$1,178
Affinity Asset Advisors, Llc Options Holdings in Q1 2026

8 options positions in the latest reporting period.

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QuarterSymbolCompanyOptionContractsNotional Value
Q1 2026SPYSPDR S&P 500PUT200,000$130,068,000
Q1 2026MRNAModerna, Inc.CALL800,000$40,640,000
Q1 2026BMYBristol-Myers Squibb CompanyCALL300,000$18,195,000
Q1 2026IBRXImmunityBio, Inc.PUT1,250,000$9,587,500
Q1 2026NVONovo Nordisk A/SCALL175,000$6,431,250
Q1 2026DNTHDianthus Therapeutics, Inc.CALL50,000$4,196,000
Q1 2026CGONCG Oncology, Inc.CALL60,000$4,060,800
Q1 2026CELCCelcuity Inc.CALL30,000$3,424,200

Notional value represents the total exposure of the options position.