MLYS Institutional Ownership & Shareholders
MINERALYS THERAPEUTICS INC (MLYS) is currently held by 216 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $2.63B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Catalys Pacific, Llc is currently the largest disclosed institutional shareholder of MLYS tracked by InsiderSet, reporting ownership valued at approximately $213.25M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $184.71M, representing an estimated loss of -13.38% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 49% of the total disclosed MLYS value among the investors covered in this analysis. Major shareholders include Catalys Pacific, Llc, Ra Capital Management, L.P., Blackrock, Inc., and several other long-term asset managers with concentrated positions in MINERALYS THERAPEUTICS INC (MLYS).
This page ranks the largest institutional MLYS shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
216
Total Reported Value
$2.63B
Largest Holder
Catalys Pacific, Llc
Largest Position
$213.25M
Insider Transactions (90d)
10
Latest Filing Quarter
Q2 2026
New Institutional Positions
50
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Catalys Pacific, Llc | 92.94% | 7,903,838 | $213,245,549 | $184,712,694 | -$28,532,855 | -13.38% | |
| Ra Capital Management, L.P. | 1.80% | 7,692,750 | $207,550,395 | $179,779,568 | -$27,770,828 | -13.38% | |
| Blackrock, Inc. | 0.00% | 5,887,038 | $158,832,288 | $137,580,078 | -$21,252,210 | -13.38% | |
| Samsara Biocapital, Llc | 13.01% | 5,871,018 | $158,400,066 | $137,205,691 | -$21,194,375 | -13.38% | |
| Fmr Llc | 0.01% | 4,511,689 | $121,725,382 | $105,438,172 | -$16,287,210 | -13.38% | |
| State Street Corp | 0.00% | 4,141,636 | $111,741,339 | $96,790,033 | -$14,951,306 | -13.38% | |
| Deerfield Management Company, L.P. | 1.11% | 3,958,000 | $106,786,840 | $92,498,460 | -$14,288,380 | -13.38% | |
| Vanguard Capital Management Llc | 0.00% | 2,756,770 | $74,377,655 | $64,425,715 | -$9,951,940 | -13.38% | |
| Laurion Capital Management Lp | 4.90% | 2,506,152 | $67,615,981 | $58,568,772 | -$9,047,209 | -13.38% | |
| Price T Rowe Associates Inc | 0.01% | 2,262,476 | $61,042,000 | $52,874,064 | -$8,167,936 | -13.38% | |
| Orbimed Advisors Llc | 1.08% | 2,110,300 | $56,935,894 | $49,317,711 | -$7,618,183 | -13.38% | |
| Capital World Investors | 0.01% | 1,997,607 | $53,895,437 | $46,684,076 | -$7,211,361 | -13.38% | |
| Armistice Capital, Llc | 1.30% | 1,736,000 | $46,837,280 | $40,570,320 | -$6,266,960 | -13.38% | |
| Troluce Capital Advisors Llc | 17.47% | 1,728,753 | $46,641,756 | $40,400,958 | -$6,240,798 | -13.38% | |
| Andera Partners | 20.80% | 1,591,917 | $42,949,921 | $37,203,100 | -$5,746,821 | -13.38% | |
| Geode Capital Management, Llc | 0.00% | 1,584,326 | $42,753,193 | $37,025,699 | -$5,727,494 | -13.40% | |
| Sr One Capital Management, Lp | 4.06% | 1,563,966 | $42,195,803 | $36,549,885 | -$5,645,918 | -13.38% | |
| Bank Of America Corp | 0.00% | 1,505,547 | $40,619,658 | $35,184,633 | -$5,435,025 | -13.38% | |
| Sphera Funds Management Ltd. | 5.68% | 1,469,971 | $39,659,818 | $34,353,222 | -$5,306,596 | -13.38% | |
| Goldman Sachs Group Inc | 0.00% | 1,458,676 | $39,355,079 | $34,089,258 | -$5,265,821 | -13.38% | |
| Pictet Asset Management Holding Sa | 0.04% | 1,430,649 | $38,598,910 | $33,434,267 | -$5,164,643 | -13.38% | |
| Polar Capital Holdings Plc | 0.11% | 1,420,854 | $38,334,641 | $33,205,358 | -$5,129,283 | -13.38% | |
| Millennium Management Llc | 0.02% | 1,221,758 | $32,963,031 | $28,552,484 | -$4,410,547 | -13.38% | |
| Ghisallo Capital Management Llc | 0.60% | 1,125,000 | $30,352,500 | $26,291,250 | -$4,061,250 | -13.38% | |
| Invesco Ltd. | 0.00% | 1,091,180 | $29,440,036 | $25,500,877 | -$3,939,159 | -13.38% | |
| Alliancebernstein L.P. | 0.01% | 1,067,541 | $28,919,686 | $24,948,433 | -$3,971,253 | -13.73% | |
| Logos Global Management Lp | 1.22% | 1,050,000 | $28,329,000 | $24,538,500 | -$3,790,500 | -13.38% | |
| American Century Companies Inc | 0.01% | 1,036,767 | $27,972,049 | $24,229,245 | -$3,742,804 | -13.38% | |
| Morgan Stanley | 0.00% | 917,213 | $24,746,440 | $21,435,268 | -$3,311,172 | -13.38% | |
| Davern Capital Partners, Lp | 3.95% | 858,753 | $23,169,156 | $20,069,058 | -$3,100,098 | -13.38% | |
| Candriam S.C.A. | 0.10% | 857,037 | $23,100,611 | $20,028,955 | -$3,071,656 | -13.30% | |
| Nantahala Capital Management, Llc | 1.34% | 820,481 | $22,136,577 | $19,174,641 | -$2,961,936 | -13.38% | |
| Wellington Management Group Llp | 0.00% | 806,716 | $21,765,199 | $18,852,953 | -$2,912,246 | -13.38% | |
| Affinity Asset Advisors, Llc | 0.99% | 750,000 | $20,235,000 | $17,527,500 | -$2,707,500 | -13.38% | |
| Vanguard Portfolio Management Llc | 0.00% | 747,657 | $20,171,786 | $17,472,744 | -$2,699,042 | -13.38% | |
| Tudor Investment Corp Et Al | 0.08% | 738,370 | $19,921,223 | $17,255,707 | -$2,665,516 | -13.38% | |
| Aberdeen Group Plc | 0.03% | 689,235 | $18,595,560 | $16,107,422 | -$2,488,138 | -13.38% | |
| Algert Global Llc | 0.21% | 649,027 | $17,510,748 | $15,167,761 | -$2,342,987 | -13.38% | |
| Pale Fire Capital Se | 1.18% | 614,284 | $16,573,382 | $14,355,817 | -$2,217,565 | -13.38% | |
| Stempoint Capital Lp | 2.81% | 602,686 | $16,260,468 | $14,084,772 | -$2,175,696 | -13.38% | |
| Northern Trust Corp | 0.00% | 551,491 | $14,879,227 | $12,888,345 | -$1,990,882 | -13.38% | |
| Charles Schwab Investment Management Inc | 0.00% | 521,216 | $14,062,408 | $12,180,818 | -$1,881,590 | -13.38% | |
| Rock Springs Capital Management Lp | 0.64% | 484,951 | $13,083,978 | $11,333,305 | -$1,750,673 | -13.38% | |
| Citadel Advisors Llc | 0.01% | 467,598 | $12,615,794 | $10,927,765 | -$1,688,029 | -13.38% | |
| Dimensional Fund Advisors Lp | 0.00% | 463,387 | $12,501,914 | $10,829,354 | -$1,672,560 | -13.38% | |
| Vanguard Fiduciary Trust Co | 0.00% | 450,370 | $12,150,983 | $10,525,147 | -$1,625,836 | -13.38% | |
| Integral Health Asset Management, Llc | 0.50% | 450,000 | $12,141,000 | $10,516,500 | -$1,624,500 | -13.38% | |
| Prosight Management, Lp | 2.09% | 449,795 | $12,135,469 | $10,511,709 | -$1,623,760 | -13.38% | |
| Catalio Capital Management, Lp | 2.13% | 331,849 | $12,042,800 | $7,755,311 | -$4,287,489 | -35.60% | |
| Rhenman & Partners Asset Management Ab | 1.06% | 416,371 | $11,233,690 | $9,730,590 | -$1,503,100 | -13.38% |
Frequently asked questions about MLYS
Who are the largest institutional holders of MLYS?
The largest institutional holders of MLYS reported in the latest SEC Form 13F filings include Catalys Pacific, Llc, Ra Capital Management, L.P., Blackrock, Inc., Samsara Biocapital, Llc, and Fmr Llc. InsiderSet ranks institutional holders by their latest reported MLYS position.
What is MLYS institutional ownership?
This page tracks MLYS positions reported by institutional investment managers through SEC Form 13F. MINERALYS THERAPEUTICS INC (MLYS) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own MLYS?
InsiderSet currently tracks 216 institutional managers reporting MLYS holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of MLYS shareholders.
How much MLYS stock do institutions own?
Institutional investment managers disclosed approximately $2.63B in MLYS holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was MLYS institutional ownership last updated?
The latest MLYS institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional MLYS holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its MLYS position after the reporting date.
Are institutions buying or selling MLYS?
Institutional buying and selling can be analyzed by comparing MLYS positions across consecutive 13F reporting periods. InsiderSet's MLYS Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View MLYS ownership changes.
How has MLYS institutional ownership changed over time?
InsiderSet tracks MLYS institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.