MINERALYS THERAPEUTICS INC (MLYS) Institutional Ownership Changes & 13F Activity
MINERALYS THERAPEUTICS INC (MLYS). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Ra Capital Management, L.P., Samsara Biocapital, Llc, Fmr Llc, Caligan Partners Lp, and Holocene Advisors, Lp.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Catalio Capital Management, Lp | Buy | +331,849 | — | 331,849 | $12.04M | Q4 2025 | Sep 02, 2026 |
| Ensign Peak Advisors, Inc | Buy | +4,550 | +4.2% | 112,190 | $4.07M | Q4 2025 | Aug 18, 2026 |
| Seven Fleet Capital Management Lp | Buy | +15,243 | — | 15,243 | $553.17K | Q4 2025 | Feb 26, 2026 |
| Ikarian Capital, Llc | Buy | +200,000 | — | 200,000 | $7.26M | Q4 2025 | Feb 18, 2026 |
| Raymond James Financial Inc | Buy | +24,974 | — | 24,974 | $906.31K | Q4 2025 | Feb 18, 2026 |
| Ra Capital Management, L.P. | Buy | +7,323,750 | — | 7,323,750 | $265.78M | Q4 2025 | Feb 17, 2026 |
| Samsara Biocapital, Llc | Buy | +5,871,018 | — | 5,871,018 | $213.06M | Q4 2025 | Feb 17, 2026 |
| Fmr Llc | Buy | +5,057,509 | — | 5,057,509 | $183.54M | Q4 2025 | Feb 17, 2026 |
| Caligan Partners Lp | Buy | +2,772,654 | — | 2,772,654 | $100.62M | Q4 2025 | Feb 17, 2026 |
| Holocene Advisors, Lp | Buy | +1,602,035 | — | 1,602,035 | $58.14M | Q4 2025 | Feb 17, 2026 |
| Andera Partners | Buy | +1,591,917 | — | 1,591,917 | $57.77M | Q4 2025 | Feb 17, 2026 |
| Suvretta Capital Management, Llc | Buy | +1,538,662 | — | 1,538,662 | $55.84M | Q4 2025 | Feb 17, 2026 |
| Polar Capital Holdings Plc | Buy | +1,401,141 | — | 1,401,141 | $50.85M | Q4 2025 | Feb 17, 2026 |
| Price T Rowe Associates Inc | Buy | +1,325,120 | — | 1,325,120 | $48.09M | Q4 2025 | Feb 17, 2026 |
| Samlyn Capital, Llc | Buy | +1,304,932 | — | 1,304,932 | $47.36M | Q4 2025 | Feb 17, 2026 |
| Janus Henderson Group Plc | Buy | +1,213,265 | — | 1,213,265 | $44.01M | Q4 2025 | Feb 17, 2026 |
| Point72 Asset Management, L.P. | Buy | +1,207,220 | — | 1,207,220 | $43.81M | Q4 2025 | Feb 17, 2026 |
| D. E. Shaw & Co., Inc. | Buy | +1,150,670 | — | 1,150,670 | $41.76M | Q4 2025 | Feb 17, 2026 |
| Boothbay Fund Management, Llc | Buy | +992,082 | — | 992,082 | $36.00M | Q4 2025 | Feb 17, 2026 |
| Bank Of America Corp | Buy | +987,280 | — | 987,280 | $35.83M | Q4 2025 | Feb 17, 2026 |
| Orbimed Advisors Llc | Buy | +980,400 | — | 980,400 | $35.58M | Q4 2025 | Feb 17, 2026 |
| Alliancebernstein L.P. | Buy | +922,516 | — | 922,516 | $33.48M | Q4 2025 | Feb 17, 2026 |
| Wellington Management Group Llp | Buy | +784,267 | — | 784,267 | $28.46M | Q4 2025 | Feb 17, 2026 |
| Integral Health Asset Management, Llc | Buy | +750,000 | — | 750,000 | $27.22M | Q4 2025 | Feb 17, 2026 |
| Armistice Capital, Llc | Buy | +676,035 | — | 676,035 | $24.53M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Investments, Lp | Buy | +610,403 | — | 610,403 | $22.15M | Q4 2025 | Feb 17, 2026 |
| Qube Research & Technologies Ltd | Buy | +496,549 | — | 496,549 | $18.02M | Q4 2025 | Feb 17, 2026 |
| Sphera Funds Management Ltd. | Buy | +449,003 | — | 449,003 | $16.29M | Q4 2025 | Feb 17, 2026 |
| Rock Springs Capital Management Lp | Buy | +427,596 | — | 427,596 | $15.52M | Q4 2025 | Feb 17, 2026 |
| Parkman Healthcare Partners Llc | Buy | +410,249 | — | 410,249 | $14.89M | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about MLYS activity
Which institutional owners are buying MLYS?
Institutional owners buying MLYS include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in MLYS activity?
"Buy" means an investor increased their reported position in MLYS compared to the prior reporting period. This reflects growing exposure to MINERALYS THERAPEUTICS INC (MLYS) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in MLYS increasing?
Institutional interest in MLYS can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related MLYS Institutional Insights
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