Ikarian Capital, Llc Portfolio Stock Holdings

Ikarian Capital, Llc disclosed 127 stock positions valued at approximately $699.0 million in its latest SEC 13F filing. The largest holdings include TERNS PHARMACEUTICALS INC, KODIAK SCIENCES INC, and ALUMIS INC. The filing reflects positions held as of March 31, 2026 and was filed on May 15, 2026.

Report Period
March 31, 2026
No. of Stocks
127
Portfolio Value
$699.0M
Holdings by Sector
Ikarian Capital, Llc Portfolio Holdings in Q1 2026

74 holdings in the latest reporting period.

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CompanySymbolSectorPortfolio %SharesChange (Shares)Change %Value
TERNS PHARMACEUTICALS INCTERNHealthcare10.98%1,456,378-140,000-8.77%$76,780,248
KODIAK SCIENCES INCKODHealthcare6.90%1,265,795+546,008+75.86%$48,252,106
ALUMIS INCALMSHealthcare3.82%1,213,548+1,213,548+100.00%$26,734,462
VAXCYTE INCPCVXHealthcare3.56%428,682+50,000+13.20%$24,910,711
PRAXIS PRECISION MEDICINES IPRAXHealthcare3.30%71,581-15,000-17.32%$23,062,682
HARROW INCHROWHealthcare2.74%543,047+359,700+196.19%$19,147,837
RELMADA THERAPEUTICS INCRLMDHealthcare2.68%2,688,359-380,000-12.38%$18,710,978
CYTOKINETICS INCCYTKHealthcare2.67%283,572+110,900+64.23%$18,690,231
TENAX THERAPEUTICS INCTENXHealthcare2.33%1,017,600+50,000+5.17%$16,271,424
CAPRICOR THERAPEUTICS INCCAPRHealthcare2.30%528,015-50,000-8.65%$16,051,656
REVOLUTION MEDICINES INCRVMDHealthcare2.27%163,142+25,000+18.10%$15,865,561
CELLDEX THERAPEUTICS INC NEWCLDXHealthcare2.09%461,247+461,247+100.00%$14,630,755
PHARVARIS N VPHVSOther1.97%486,856--$13,753,683
BRIDGEBIO PHARMA INCBBIOHealthcare1.70%160,120+160,120+100.00%$11,890,511
ALTO NEUROSCIENCE INCANROHealthcare1.66%515,000--$11,577,200
SOLENO THERAPEUTICS INCSLNOHealthcare1.65%344,123+275,300+400.01%$11,521,238
ANI PHARMACEUTICALS INCANIPHealthcare1.62%147,085+147,085+100.00%$11,310,837
CONTINEUM THERAPEUTICS INCCTNMHealthcare1.51%807,874+525,000+185.59%$10,550,835
ULTRAGENYX PHARMACEUTICAL INRAREHealthcare1.45%482,571+469,900+3708.47%$10,109,863
IONIS PHARMACEUTICALS INCIONSHealthcare1.36%127,038-75,000-37.12%$9,539,284
OLEMA PHARMACEUTICALS INCOLMAHealthcare1.28%598,281-160,373-21.14%$8,920,370
FULCRUM THERAPEUTICS INCFULCHealthcare1.15%1,049,161-326,311-23.72%$8,047,065
VERA THERAPEUTICS INCVERAHealthcare1.15%200,000+200,000+100.00%$8,045,999
OCUGEN INCOCGNHealthcare1.03%3,962,972+3,962,972+100.00%$7,172,979
OVID THERAPEUTICS INCOVIDHealthcare0.92%2,894,704+2,647,146+1069.30%$6,426,242
ABIVAX SAABVXHealthcare0.89%57,635-148,350-72.02%$6,232,692
ELI LILLY & COLLYHealthcare0.86%6,547-7,268-52.61%$6,021,734
SURROZEN INCSRZNHealthcare0.72%173,107+107,319+163.13%$5,042,607
TECTONIC THERAPEUTIC INCTECXHealthcare0.70%157,537+157,537+100.00%$4,869,469
ALECTOR INCALECHealthcare0.64%2,082,606--$4,477,603
LEGEND BIOTECH CORPLEGNHealthcare0.59%226,888--$4,104,404
LIPOCINE INC NEWLPCNHealthcare0.58%508,556+309,014+154.86%$4,063,362
DELCATH SYS INCDCTHHealthcare0.57%431,251--$4,002,009
ARVINAS INCARVNHealthcare0.54%358,257--$3,797,524
COMPASS PATHWAYS PLCCMPSHealthcare0.53%675,000+275,000+68.75%$3,732,750
CARDIOL THERAPEUTICS INCCRDLHealthcare0.53%2,725,000+2,725,000+100.00%$3,678,750
INVIVYD INCIVVDHealthcare0.49%2,656,570--$3,453,542
ANNEXON INCANNXHealthcare0.46%580,244+350,000+152.01%$3,214,551
LEXEO THERAPEUTICS INCLXEOHealthcare0.42%513,011--$2,944,683
VIR BIOTECHNOLOGY INCVIRHealthcare0.38%293,258-282,454-49.06%$2,627,591
NEUMORA THERAPEUTICS INC.NMRAHealthcare0.36%1,278,408--$2,492,896
ACUMEN PHARMACEUTICALS INCABOSHealthcare0.36%1,053,797+799,485+314.37%$2,486,960
CABALETTA BIO INCCABAHealthcare0.35%900,000--$2,421,000
NUVALENT INCNUVLHealthcare0.35%23,594-36,000-60.41%$2,417,206
TARSUS PHARMACEUTICALS INCTARSHealthcare0.31%31,166--$2,186,295
SOLID BIOSCIENCES INCSLDBHealthcare0.27%264,409+104,000+64.83%$1,903,744
IBIO INCIBIOHealthcare0.26%957,062--$1,818,418
CUMBERLAND PHARMACEUTICALS ICPIXHealthcare0.26%553,153-2,779-0.50%$1,797,748
SILENCE THERAPEUTICS PLCSLNHealthcare0.25%865,784--$1,731,568
JOURNEY MED CORPDERMHealthcare0.17%251,436--$1,179,235
VERASTEM INCVSTMHealthcare0.16%213,865--$1,133,484
NEURONETICS INCSTIMHealthcare0.15%701,182--$1,016,714
PEPGEN INCPEPGHealthcare0.11%447,165--$791,482
IMMUNIC INCIMUXHealthcare0.11%674,662--$748,876
CENTESSA PHARMACEUTICALS PLCCNTAHealthcare0.10%18,113+18,113+100.00%$719,448
KALVISTA PHARMACEUTICALS INCKALVHealthcare0.10%35,119--$706,946
INSMED INCINSMHealthcare0.10%4,214-5,123-54.87%$689,074
ACADIA PHARMACEUTICALS INCACADHealthcare0.09%28,099+28,099+100.00%$625,484
EQUILLIUM INCEQHealthcare0.09%303,555--$607,110
FRACTYL HEALTH INCGUTSHealthcare0.07%1,100,000--$503,580
VIKING THERAPEUTICS INCVKTXHealthcare0.05%9,717--$316,191
SANGAMO THERAPEUTICS INCSGMOHealthcare0.04%1,218,671--$300,890
VISTAGEN THERAPEUTICS INCVTGNHealthcare0.04%519,077--$296,654
LEXICON PHARMACEUTICALS INCLXRXHealthcare0.04%164,674--$256,892
MACROGENICS INCMGNXHealthcare0.03%74,893--$216,441
VOYAGER THERAPEUTICS INCVYGRHealthcare0.03%53,063--$204,823
VYNE THERAPEUTICS INCVYNEHealthcare0.02%264,912--$158,284
CARTESIAN THERAPEUTICS INCRNACHealthcare0.02%20,807--$127,963
PMV PHARMACEUTICALS INCPMVPHealthcare0.02%89,136--$110,529
COMPASS THERAPEUTICS INCCMPXHealthcare0.01%18,000-782,000-97.75%$95,220
IO BIOTECH INCIOBTHealthcare0.01%1,386,565--$81,391
REZOLUTE INCRZLTHealthcare0.01%16,479--$50,261
AIRSCULPT TECHNOLOGIES INCAIRSHealthcare0.01%16,398--$46,405
JASPER THERAPEUTICS INCJSPRHealthcare0.00%24,093--$21,110
Ikarian Capital, Llc Options Holdings in Q1 2026

28 options positions in the latest reporting period.

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QuarterSymbolCompanyOptionContractsNotional Value
Q1 2026XBISPDR Series Trust SPDR S&P BioPUT800,000$102,184,000
Q1 2026TERNTerns Pharmaceuticals, Inc.PUT1,200,000$63,264,000
Q1 2026QQQInvesco QQQ Trust, Series 1PUT100,000$57,718,000
Q1 2026IWMiShares Russell 2000 ETFPUT200,000$49,600,000
Q1 2026CYTKCytokinetics, IncorporatedPUT550,500$36,283,455
Q1 2026ABVXAbivax SACALL293,300$32,658,955
Q1 2026BMYBristol-Myers Squibb CompanyPUT500,000$30,325,000
Q1 2026CYTKCytokinetics, IncorporatedCALL408,400$26,917,644
Q1 2026NVONovo Nordisk A/SCALL400,000$14,700,000
Q1 2026ANIPANI Pharmaceuticals, Inc.CALL150,000$11,535,000
Q1 2026CAPRCapricor Therapeutics, Inc.CALL350,000$10,640,000
Q1 2026RVMDRevolution Medicines, Inc.PUT95,000$9,238,750
Q1 2026IONSIonis Pharmaceuticals, Inc.CALL112,100$8,417,589
Q1 2026OLMAOlema Pharmaceuticals, Inc.CALL549,800$8,197,518
Q1 2026AVTXAvalo Therapeutics, Inc.CALL401,500$5,994,395
Q1 2026ALMSAlumis Inc.CALL264,600$5,829,138
Q1 2026EYPTEyePoint Pharmaceuticals, Inc.CALL370,400$4,774,456
Q1 2026BBIOBridgeBio Pharma, Inc.CALL58,500$4,344,210
Q1 2026KYMRKymera Therapeutics, Inc.PUT50,400$4,197,816
Q1 2026KODKodiak Sciences IncCALL100,000$3,812,000
Q1 2026CLDXCelldex Therapeutics, Inc.PUT114,000$3,616,080
Q1 2026ARWRArrowhead Pharmaceuticals, Inc.PUT57,500$3,605,250
Q1 2026ELVNEnliven Therapeutics, Inc.PUT83,700$3,281,040
Q1 2026VERAVera Therapeutics, Inc.CALL71,700$2,884,491
Q1 2026AVTXAvalo Therapeutics, Inc.PUT158,500$2,366,405
Q1 2026REPLReplimune Group, Inc.PUT300,000$2,295,000
Q1 2026TENXTenax Therapeutics, Inc.CALL114,300$1,827,657
Q1 2026PEPGPepGen Inc.CALL300,000$531,000

Notional value represents the total exposure of the options position.