Maze Therapeutics, Inc. (MAZE) Institutional Shareholders
Maze Therapeutics, Inc. (MAZE) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $1.70B in MAZE holdings during the latest filing period.
Frazier Life Sciences Management, L.P. is currently the largest disclosed institutional shareholder of MAZE tracked by InsiderSet, reporting ownership valued at approximately $150.18M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $113.34M, representing an estimated loss of -24.53% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 56% of the total disclosed MAZE value among the investors covered in this analysis. Major shareholders include Frazier Life Sciences Management, L.P., Trv Gp Iv, Llc, Arch Venture Management, Llc, and several other long-term asset managers with concentrated positions in Maze Therapeutics, Inc. (MAZE).
This page ranks the largest institutional MAZE shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
156
Total Reported Value
$1.70B
Largest Holder
Frazier Life Sciences Management, L.P.
Largest Position
$150.18M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
103
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 3.27% | 5,032,915 | $150,182,184 | $113,341,246 | -$36,840,938 | -24.53% | |
| Trv Gp Iv, Llc | 52.63% | 4,473,958 | $133,502,907 | $100,753,534 | -$32,749,373 | -24.53% | |
| Arch Venture Management, Llc | 11.18% | 4,120,053 | $122,983,582 | $92,783,594 | -$30,199,988 | -24.56% | |
| Deep Track Capital, Lp | 1.64% | 3,732,569 | $111,379,859 | $84,057,454 | -$27,322,405 | -24.53% | |
| Blackrock, Inc. | 0.00% | 3,502,841 | $104,524,775 | $78,883,979 | -$25,640,796 | -24.53% | |
| Janus Henderson Group Plc | 0.04% | 2,858,876 | $85,280,271 | $64,381,888 | -$20,898,383 | -24.51% | |
| T. Rowe Price Investment Management, Inc. | 0.05% | 2,603,682 | $77,694,000 | $58,634,919 | -$19,059,081 | -24.53% | |
| Logos Global Management Lp | 2.49% | 1,935,000 | $57,740,400 | $43,576,200 | -$14,164,200 | -24.53% | |
| Vanguard Capital Management Llc | 0.00% | 1,778,222 | $53,062,144 | $40,045,559 | -$13,016,585 | -24.53% | |
| A16Z Capital Management, L.L.C. | 0.36% | 1,702,225 | $50,794,394 | $38,334,107 | -$12,460,287 | -24.53% | |
| Venrock Adviser, Llc | 1.45% | 1,602,034 | $47,804,695 | $36,077,806 | -$11,726,889 | -24.53% | |
| Alphabet Inc. | 0.04% | 1,388,583 | $41,435,317 | $31,270,889 | -$10,164,428 | -24.53% | |
| Braidwell Lp | 1.26% | 1,140,040 | $34,018,794 | $25,673,701 | -$8,345,093 | -24.53% | |
| Fmr Llc | 0.00% | 1,056,959 | $31,539,649 | $23,802,717 | -$7,736,932 | -24.53% | |
| General Catalyst Group Management, Llc | 16.40% | 1,035,910 | $30,911,554 | $23,328,693 | -$7,582,861 | -24.53% | |
| State Street Corp | 0.00% | 997,533 | $29,766,385 | $22,464,443 | -$7,301,942 | -24.53% | |
| Driehaus Capital Management Llc | 0.17% | 954,886 | $28,493,798 | $21,504,033 | -$6,989,765 | -24.53% | |
| Trv Gp V, Llc | 5.69% | 950,800 | $28,371,872 | $21,412,016 | -$6,959,856 | -24.53% | |
| Jpmorgan Chase & Co | 0.00% | 964,011 | $27,995,382 | $21,709,528 | -$6,285,854 | -22.45% | |
| Marshall Wace, Llp | 0.02% | 914,572 | $27,290,827 | $20,596,161 | -$6,694,666 | -24.53% | |
| Geode Capital Management, Llc | 0.00% | 858,054 | $25,608,436 | $19,323,376 | -$6,285,060 | -24.54% | |
| Citadel Advisors Llc | 0.01% | 852,676 | $25,443,852 | $19,202,264 | -$6,241,588 | -24.53% | |
| Casdin Capital, Llc | 1.26% | 843,857 | $25,180,693 | $19,003,660 | -$6,177,033 | -24.53% | |
| Arrowmark Colorado Holdings Llc | 0.95% | 767,383 | $22,898,709 | $17,281,465 | -$5,617,244 | -24.53% | |
| Woodline Partners Lp | 0.07% | 736,216 | $21,968,685 | $16,579,584 | -$5,389,101 | -24.53% | |
| Bessemer Group Inc | 0.02% | 481,790 | $14,377,000 | $10,849,911 | -$3,527,089 | -24.53% | |
| Sphera Funds Management Ltd. | 1.78% | 417,564 | $12,460,110 | $9,403,541 | -$3,056,569 | -24.53% | |
| Vanguard Portfolio Management Llc | 0.00% | 393,107 | $11,730,313 | $8,852,770 | -$2,877,543 | -24.53% | |
| Aberdeen Group Plc | 0.02% | 383,773 | $11,451,786 | $8,642,568 | -$2,809,218 | -24.53% | |
| Ikarian Capital, Llc | 1.85% | 378,999 | $11,309,331 | $8,535,057 | -$2,774,274 | -24.53% | |
| Hhlr Advisors, Ltd. | 1.31% | 366,028 | $10,922,276 | $8,242,951 | -$2,679,325 | -24.53% | |
| Adar1 Capital Management, Llc | 0.48% | 339,276 | $10,123,996 | $7,640,496 | -$2,483,500 | -24.53% | |
| Squadron Capital Management Llc | 3.42% | 335,000 | $9,996,400 | $7,544,200 | -$2,452,200 | -24.53% | |
| Bank Of America Corp | 0.00% | 321,227 | $9,585,414 | $7,234,032 | -$2,351,382 | -24.53% | |
| Northern Trust Corp | 0.00% | 294,742 | $8,795,101 | $6,637,590 | -$2,157,511 | -24.53% | |
| Goldman Sachs Group Inc | 0.00% | 293,144 | $8,747,417 | $6,601,603 | -$2,145,814 | -24.53% | |
| Candriam S.C.A. | 0.04% | 273,932 | $8,166,266 | $6,168,949 | -$1,997,317 | -24.46% | |
| Hudson Bay Capital Management Lp | 0.04% | 270,000 | $8,056,800 | $6,080,400 | -$1,976,400 | -24.53% | |
| Charles Schwab Investment Management Inc | 0.00% | 260,566 | $7,775,289 | $5,867,946 | -$1,907,343 | -24.53% | |
| Adage Capital Partners Gp, L.L.C. | 0.01% | 248,000 | $7,400,320 | $5,584,960 | -$1,815,360 | -24.53% | |
| Mass General Brigham, Inc | 1.98% | 239,994 | $7,161,421 | $5,404,665 | -$1,756,756 | -24.53% | |
| Ameriprise Financial Inc | 0.00% | 227,425 | $6,786,363 | $5,121,611 | -$1,664,752 | -24.53% | |
| Vanguard Fiduciary Trust Co | 0.00% | 219,938 | $6,562,950 | $4,953,004 | -$1,609,946 | -24.53% | |
| Rtw Investments, Lp | 0.05% | 212,000 | $6,326,080 | $4,774,240 | -$1,551,840 | -24.53% | |
| Schroder Investment Management Group | 0.00% | 199,872 | $5,796,288 | $4,501,117 | -$1,295,171 | -22.34% | |
| Two Sigma Investments, Lp | 0.00% | 192,952 | $5,757,688 | $4,345,279 | -$1,412,409 | -24.53% | |
| Boothbay Fund Management, Llc | 0.11% | 188,857 | $5,635,493 | $4,253,060 | -$1,382,433 | -24.53% | |
| Ensign Peak Advisors, Inc | 0.01% | 185,794 | $5,545,951 | $4,184,081 | -$1,361,870 | -24.56% | |
| Exoduspoint Capital Management, Lp | 0.05% | 183,264 | $5,468,598 | $4,127,105 | -$1,341,493 | -24.53% | |
| Summittx Capital, L.P. | 0.14% | 176,291 | $5,260,523 | $3,970,073 | -$1,290,450 | -24.53% |
Frequently asked questions about MAZE
Who owns the most MAZE stock?
The largest holders of MAZE are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for Maze Therapeutics, Inc. (MAZE).
Is MAZE widely held by superinvestors?
Many widely followed stocks like MAZE appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly MAZE is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.