Frazier Life Sciences Management, L.P. Portfolio Stock Holdings

Frazier Life Sciences Management, L.P. disclosed 38 stock positions valued at approximately $3.9 billion in its latest SEC 13F filing. The largest holdings include MIRUM PHARMACEUTICALS INC, NEWAMSTERDAM PHARMA COMPANY, and ERASCA INC. The filing reflects positions held as of March 31, 2026 and was filed on May 15, 2026.

Report Period
March 31, 2026
No. of Stocks
38
Portfolio Value
$3.9B
Holdings by Sector
Frazier Life Sciences Management, L.P. Portfolio Holdings in Q1 2026

31 holdings in the latest reporting period.

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CompanySymbolSectorPortfolio %SharesChange (Shares)Change %Value
MIRUM PHARMACEUTICALS INCMIRMHealthcare18.25%7,679,684+884,563+13.02%$709,449,208
NEWAMSTERDAM PHARMA COMPANYNAMSWOther13.96%16,943,774--$542,370,206
ERASCA INCERASHealthcare10.27%24,675,188+1,945,752+8.56%$399,244,542
BRIDGEBIO PHARMA INCBBIOHealthcare6.59%3,448,139-97,418-2.75%$256,058,802
ARCUTIS BIOTHERAPEUTICS INCARQTHealthcare5.99%9,874,511--$232,643,479
PHATHOM PHARMACEUTICALS INCPHATHealthcare3.56%12,466,489--$138,502,693
KRYSTAL BIOTECH INCKRYSHealthcare3.20%481,307-7,153-1.46%$124,331,224
TREVI THERAPEUTICS INCTRVIHealthcare3.05%9,939,547-319,862-3.12%$118,578,796
KALVISTA PHARMACEUTICALS INCKALVHealthcare2.57%4,961,108-78,759-1.56%$99,867,104
DISC MEDICINE INCIRONHealthcare2.23%1,354,852+94,852+7.53%$86,629,237
CYTOKINETICS INCCYTKHealthcare1.97%1,159,879+225,237+24.10%$76,447,625
REVOLUTION MEDICINES INCRVMDHealthcare1.69%675,686-121,769-15.27%$65,710,464
DYNE THERAPEUTICS INCDYNHealthcare1.47%3,153,082--$57,165,377
SAVARA INCSVRAHealthcare1.37%9,720,852-141,449-1.43%$53,075,852
TARSUS PHARMACEUTICALS INCTARSHealthcare1.32%728,644--$51,114,377
AGIOS PHARMACEUTICALS INCAGIOHealthcare1.09%1,256,080-23,674-1.85%$42,493,186
BIOCRYST PHARMACEUTICALS INCBCRXHealthcare0.98%4,009,240+4,009,240+100.00%$38,167,965
ZAI LAB LTDZLABHealthcare0.92%1,902,320--$35,782,639
AURA BIOSCIENCES INCAURAHealthcare0.88%5,100,000--$34,119,000
ACADIA PHARMACEUTICALS INCACADHealthcare0.82%1,438,198+141,000+10.87%$32,014,287
ASCENDIS PHARMA A/SASNDHealthcare0.78%133,333--$30,497,257
LEXEO THERAPEUTICS INCLXEOHealthcare0.65%4,424,725--$25,397,922
ALKERMES PLCG01767105Other0.64%700,647--$24,774,878
ACLARIS THERAPEUTICS INCACRSHealthcare0.48%4,925,374+4,925,374+100.00%$18,470,153
MONTE ROSA THERAPEUTICS INCGLUEHealthcare0.42%1,000,000+1,000,000+100.00%$16,450,000
IMMUNOCORE HLDGS PLCIMCRHealthcare0.38%484,782+100,000+25.99%$14,616,177
MANNKIND CORPMNKDHealthcare0.37%5,900,000+1,675,000+39.64%$14,455,000
EVOLUS INCEOLSHealthcare0.28%2,630,665--$10,812,033
ALLOGENE THERAPEUTICS INCALLOHealthcare0.24%3,796,668-72,082-1.86%$9,263,870
AUTOLUS THERAPEUTICS LTDAUTLHealthcare0.16%4,447,910-175,414-3.79%$6,138,116
IBIO INCIBIOHealthcare0.10%1,953,467--$3,711,587