DYNE THERAPEUTICS INC (DYN) Institutional Shareholders
DYNE THERAPEUTICS INC (DYN) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $2.76B in DYN holdings during the latest filing period.
Janus Henderson Group Plc is currently the largest disclosed institutional shareholder of DYN tracked by InsiderSet, reporting ownership valued at approximately $247.43M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $343.64M, representing an estimated gain of +38.89% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 51% of the total disclosed DYN value among the investors covered in this analysis. Major shareholders include Janus Henderson Group Plc, Blackrock, Inc., Atlas Venture Life Science Advisors, Llc, and several other long-term asset managers with concentrated positions in DYNE THERAPEUTICS INC (DYN).
This page ranks the largest institutional DYN shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
230
Total Reported Value
$2.76B
Largest Holder
Janus Henderson Group Plc
Largest Position
$247.43M
Insider Transactions (90d)
40
Latest Filing Quarter
Q2 2026
New Institutional Positions
112
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Janus Henderson Group Plc | 0.12% | 13,647,376 | $247,426,927 | $343,640,928 | +$96,214,001 | +38.89% | |
| Blackrock, Inc. | 0.00% | 11,699,870 | $212,118,644 | $294,602,727 | +$82,484,083 | +38.89% | |
| Atlas Venture Life Science Advisors, Llc | 20.95% | 9,130,465 | $165,535,330 | $229,905,109 | +$64,369,779 | +38.89% | |
| Fmr Llc | 0.01% | 8,908,980 | $161,519,805 | $224,328,116 | +$62,808,311 | +38.89% | |
| Orbis Allan Gray Ltd | 0.52% | 6,762,231 | $122,599,248 | $170,272,977 | +$47,673,729 | +38.89% | |
| State Street Corp | 0.00% | 6,653,746 | $120,632,415 | $167,541,324 | +$46,908,909 | +38.89% | |
| Vanguard Capital Management Llc | 0.00% | 6,405,069 | $116,123,901 | $161,279,637 | +$45,155,736 | +38.89% | |
| Perceptive Advisors Llc | 1.67% | 4,668,839 | $84,646,051 | $117,561,366 | +$32,915,315 | +38.89% | |
| Fcpm Iii Services B.V. | 11.66% | 4,644,386 | $84,202,718 | $116,945,639 | +$32,742,921 | +38.89% | |
| Tcg Crossover Management, Llc | 2.39% | 4,615,144 | $83,672,561 | $116,209,326 | +$32,536,765 | +38.89% | |
| Vanguard Portfolio Management Llc | 0.00% | 4,162,041 | $75,457,803 | $104,800,192 | +$29,342,389 | +38.89% | |
| Vestal Point Capital, Lp | 2.03% | 4,000,000 | $72,520,000 | $100,720,000 | +$28,200,000 | +38.89% | |
| Geode Capital Management, Llc | 0.00% | 3,504,114 | $63,542,557 | $88,233,591 | +$24,691,034 | +38.86% | |
| Armistice Capital, Llc | 1.90% | 3,175,110 | $57,564,744 | $79,949,270 | +$22,384,526 | +38.89% | |
| Frazier Life Sciences Management, L.P. | 1.47% | 3,153,082 | $57,165,377 | $79,394,605 | +$22,229,228 | +38.89% | |
| Orbimed Advisors Llc | 1.15% | 2,917,884 | $52,901,237 | $73,472,319 | +$20,571,082 | +38.89% | |
| Siren, L.L.C. | 1.12% | 2,229,125 | $40,414,036 | $56,129,368 | +$15,715,332 | +38.89% | |
| Venrock Adviser, Llc | 1.47% | 2,173,913 | $39,413,043 | $54,739,129 | +$15,326,086 | +38.89% | |
| Franklin Resources Inc | 0.01% | 2,009,082 | $36,424,648 | $50,588,685 | +$14,164,037 | +38.89% | |
| Deep Track Capital, Lp | 0.75% | 2,000,000 | $36,260,000 | $50,360,000 | +$14,100,000 | +38.89% | |
| Samlyn Capital, Llc | 0.60% | 1,922,543 | $34,855,705 | $48,409,633 | +$13,553,928 | +38.89% | |
| Aberdeen Group Plc | 0.05% | 1,539,434 | $34,190,829 | $38,762,948 | +$4,572,119 | +13.37% | |
| Goldman Sachs Group Inc | 0.00% | 1,723,116 | $31,240,093 | $43,388,061 | +$12,147,968 | +38.89% | |
| Braidwell Lp | 1.02% | 1,681,998 | $30,494,624 | $42,352,710 | +$11,858,086 | +38.89% | |
| Palo Alto Investors Lp | 4.58% | 1,652,972 | $29,968,382 | $41,621,835 | +$11,653,453 | +38.89% | |
| Sofinnova Investments, Inc. | 1.48% | 1,633,897 | $29,622,553 | $41,141,526 | +$11,518,973 | +38.89% | |
| Vivo Capital, Llc | 2.36% | 1,557,466 | $28,236,859 | $39,216,994 | +$10,980,135 | +38.89% | |
| Bank Of America Corp | 0.00% | 1,443,313 | $26,167,264 | $36,342,621 | +$10,175,357 | +38.89% | |
| Mpm Bioimpact Llc | 1.97% | 1,408,152 | $25,529,796 | $35,457,267 | +$9,927,471 | +38.89% | |
| Logos Global Management Lp | 1.31% | 1,400,000 | $25,382,000 | $35,252,000 | +$9,870,000 | +38.89% | |
| Fiera Capital Corp | 0.09% | 1,380,620 | $25,030,641 | $34,764,012 | +$9,733,371 | +38.89% | |
| Polar Capital Holdings Plc | 0.11% | 1,359,169 | $24,641,734 | $34,223,875 | +$9,582,141 | +38.89% | |
| Northern Trust Corp | 0.00% | 1,198,838 | $21,734,932 | $30,186,741 | +$8,451,809 | +38.89% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,158,390 | $21,001,611 | $29,168,260 | +$8,166,649 | +38.89% | |
| Adage Capital Partners Gp, L.L.C. | 0.03% | 1,000,000 | $18,130,000 | $25,180,000 | +$7,050,000 | +38.89% | |
| Rock Springs Capital Management Lp | 1.04% | 972,198 | $17,625,950 | $24,479,946 | +$6,853,996 | +38.89% | |
| Saturn V Capital Management Lp | 3.17% | 966,609 | $17,524,621 | $24,339,215 | +$6,814,594 | +38.89% | |
| Dimensional Fund Advisors Lp | 0.00% | 951,589 | $17,244,372 | $23,961,011 | +$6,716,639 | +38.95% | |
| Vanguard Fiduciary Trust Co | 0.00% | 947,438 | $17,177,051 | $23,856,489 | +$6,679,438 | +38.89% | |
| Morgan Stanley | 0.00% | 929,003 | $16,842,827 | $23,392,296 | +$6,549,469 | +38.89% | |
| Squarepoint Ops Llc | 0.03% | 834,176 | $15,123,611 | $21,004,552 | +$5,880,941 | +38.89% | |
| Frontier Capital Management Co Llc | 0.15% | 821,849 | $14,900,122 | $20,694,158 | +$5,794,036 | +38.89% | |
| Baker Bros. Advisors Lp | 0.08% | 813,449 | $14,747,830 | $20,482,646 | +$5,734,816 | +38.89% | |
| Nuveen, Llc | 0.00% | 718,333 | $13,023,378 | $18,087,625 | +$5,064,247 | +38.89% | |
| Arrowmark Colorado Holdings Llc | 0.32% | 673,949 | $12,218,695 | $16,970,036 | +$4,751,341 | +38.89% | |
| Artisan Partners Limited Partnership | 0.02% | 619,457 | $11,230,755 | $15,597,927 | +$4,367,172 | +38.89% | |
| Wasatch Advisors Lp | 0.06% | 443,668 | $9,853,866 | $11,171,560 | +$1,317,694 | +13.37% | |
| Renaissance Technologies LLC | Jim Simons | 0.02% | 533,600 | $9,674,168 | $13,436,048 | +$3,761,880 | +38.89% |
| Td Asset Management Inc | 0.01% | 529,312 | $9,596,427 | $13,328,076 | +$3,731,649 | +38.89% | |
| Stempoint Capital Lp | 1.79% | 506,075 | $9,175,140 | $12,742,969 | +$3,567,829 | +38.89% |
Frequently asked questions about DYN
Who owns the most DYN stock?
The largest holders of DYN are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for DYNE THERAPEUTICS INC (DYN).
Is DYN widely held by superinvestors?
Many widely followed stocks like DYN appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly DYN is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.