LXEO Institutional Ownership & Shareholders
LEXEO THERAPEUTICS INC (LXEO) is currently held by 143 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $417.22M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Suvretta Capital Management, Llc is currently the largest disclosed institutional shareholder of LXEO tracked by InsiderSet, reporting ownership valued at approximately $29.72M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $19.54M, representing an estimated loss of -34.26% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed LXEO value among the investors covered in this analysis. Major shareholders include Suvretta Capital Management, Llc, Janus Henderson Group Plc, Affinity Asset Advisors, Llc, and several other long-term asset managers with concentrated positions in LEXEO THERAPEUTICS INC (LXEO).
This page ranks the largest institutional LXEO shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
143
Total Reported Value
$417.22M
Largest Holder
Suvretta Capital Management, Llc
Largest Position
$29.72M
Insider Transactions (90d)
6
Latest Filing Quarter
Q2 2026
New Institutional Positions
88
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Suvretta Capital Management, Llc | 0.62% | 6,384,200 | $29,718,451 | $19,535,652 | -$10,182,799 | -34.26% | |
| Janus Henderson Group Plc | 0.01% | 4,976,429 | $28,510,358 | $15,227,873 | -$13,282,485 | -46.59% | |
| Affinity Asset Advisors, Llc | 1.32% | 5,807,611 | $27,034,429 | $17,771,290 | -$9,263,139 | -34.26% | |
| Blackrock, Inc. | 0.00% | 5,739,455 | $26,717,165 | $17,562,732 | -$9,154,433 | -34.26% | |
| Ra Capital Management, L.P. | 0.20% | 5,000,000 | $23,275,000 | $15,300,000 | -$7,975,000 | -34.26% | |
| Frazier Life Sciences Management, L.P. | 0.49% | 4,824,725 | $22,459,095 | $14,763,659 | -$7,695,437 | -34.26% | |
| State Street Corp | 0.00% | 4,354,757 | $20,271,394 | $13,325,556 | -$6,945,838 | -34.26% | |
| Vestal Point Capital, Lp | 0.47% | 4,320,000 | $20,109,600 | $13,219,200 | -$6,890,400 | -34.26% | |
| Paradigm Biocapital Advisors Lp | 0.36% | 4,175,382 | $19,436,403 | $12,776,669 | -$6,659,734 | -34.26% | |
| Orbimed Advisors Llc | 0.35% | 3,947,850 | $18,377,242 | $12,080,421 | -$6,296,821 | -34.26% | |
| Citadel Advisors Llc | 0.01% | 3,898,570 | $18,147,843 | $11,929,624 | -$6,218,219 | -34.26% | |
| Vanguard Capital Management Llc | 0.00% | 3,125,893 | $14,551,032 | $9,565,233 | -$4,985,799 | -34.26% | |
| Millennium Management Llc | 0.01% | 2,833,622 | $13,190,510 | $8,670,883 | -$4,519,627 | -34.26% | |
| Woodline Partners Lp | 0.04% | 2,500,532 | $11,639,976 | $7,651,628 | -$3,988,348 | -34.26% | |
| Balyasny Asset Management L.P. | 0.02% | 2,412,742 | $11,231,314 | $7,382,991 | -$3,848,323 | -34.26% | |
| Goldman Sachs Group Inc | 0.00% | 2,149,612 | $10,006,444 | $6,577,813 | -$3,428,631 | -34.26% | |
| 683 Capital Management, Llc | 0.80% | 1,875,000 | $8,728,124 | $5,737,500 | -$2,990,624 | -34.26% | |
| Geode Capital Management, Llc | 0.00% | 1,747,959 | $8,138,547 | $5,348,755 | -$2,789,792 | -34.28% | |
| Adar1 Capital Management, Llc | 0.34% | 1,565,950 | $7,289,497 | $4,791,807 | -$2,497,690 | -34.26% | |
| Avoro Capital Advisors Llc | 0.06% | 1,489,189 | $6,932,175 | $4,556,918 | -$2,375,257 | -34.26% | |
| Qube Research & Technologies Ltd | 0.01% | 1,376,222 | $6,406,313 | $4,211,239 | -$2,195,074 | -34.26% | |
| Nantahala Capital Management, Llc | 0.37% | 1,300,000 | $6,051,500 | $3,978,000 | -$2,073,500 | -34.26% | |
| Dimensional Fund Advisors Lp | 0.00% | 1,287,185 | $5,992,745 | $3,938,786 | -$2,053,959 | -34.27% | |
| Spruce Street Capital Lp | 0.85% | 928,593 | $4,322,600 | $2,841,495 | -$1,481,105 | -34.26% | |
| Northern Trust Corp | 0.00% | 867,391 | $4,037,705 | $2,654,216 | -$1,383,489 | -34.26% | |
| Aberdeen Group Plc | 0.00% | 675,092 | $3,142,553 | $2,065,782 | -$1,076,771 | -34.26% | |
| Vanguard Portfolio Management Llc | 0.00% | 613,826 | $2,857,360 | $1,878,308 | -$979,052 | -34.26% | |
| Ikarian Capital, Llc | 0.39% | 513,011 | $2,388,066 | $1,569,814 | -$818,252 | -34.26% | |
| Bank Of America Corp | 0.00% | 490,331 | $2,282,490 | $1,500,413 | -$782,077 | -34.26% | |
| Vanguard Fiduciary Trust Co | 0.00% | 430,696 | $2,004,890 | $1,317,930 | -$686,960 | -34.26% | |
| Morgan Stanley | 0.00% | 395,102 | $1,839,200 | $1,209,012 | -$630,188 | -34.26% | |
| Bnp Paribas Financial Markets | 0.00% | 388,398 | $1,807,993 | $1,188,498 | -$619,495 | -34.26% | |
| Dafna Capital Management Llc | 0.33% | 377,059 | $1,755,210 | $1,153,801 | -$601,409 | -34.26% | |
| Ubs Group Ag | 0.00% | 354,044 | $1,648,074 | $1,083,375 | -$564,699 | -34.26% | |
| Trexquant Investment Lp | 0.01% | 314,891 | $1,465,818 | $963,566 | -$502,252 | -34.26% | |
| Squarepoint Ops Llc | 0.00% | 294,774 | $1,372,173 | $902,008 | -$470,165 | -34.26% | |
| Hennion & Walsh Asset Management, Inc. | 0.04% | 381,989 | $1,291,123 | $1,168,886 | -$122,237 | -9.47% | |
| Aqr Capital Management Llc | 0.00% | 256,661 | $1,194,757 | $785,383 | -$409,374 | -34.26% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 250,365 | $1,165,449 | $766,117 | -$399,332 | -34.26% |
| Wellington Management Group Llp | 0.00% | 202,383 | $942,093 | $619,292 | -$322,801 | -34.26% | |
| Nuveen, Llc | 0.00% | 200,417 | $932,941 | $613,276 | -$319,665 | -34.26% | |
| Bank Of New York Mellon Corp | 0.00% | 183,883 | $855,975 | $562,682 | -$293,293 | -34.26% | |
| Charles Schwab Investment Management Inc | 0.00% | 172,609 | $803,495 | $528,184 | -$275,311 | -34.26% | |
| Susquehanna Portfolio Strategies, Llc | 0.01% | 161,062 | $749,744 | $492,850 | -$256,894 | -34.26% | |
| Xtx Topco Ltd | 0.01% | 145,556 | $677,563 | $445,401 | -$232,162 | -34.26% | |
| Fmr Llc | 0.00% | 141,146 | $657,035 | $431,907 | -$225,128 | -34.26% | |
| Boothbay Fund Management, Llc | 0.01% | 136,377 | $634,835 | $417,314 | -$217,521 | -34.26% | |
| Creative Planning | 0.00% | 177,252 | $599,112 | $542,391 | -$56,721 | -9.47% | |
| Burkehill Global Management, Lp | 0.02% | 125,000 | $581,875 | $382,500 | -$199,375 | -34.26% | |
| Raymond James Financial Inc | 0.00% | 117,388 | $546,441 | $359,207 | -$187,234 | -34.26% |
Frequently asked questions about LXEO
Who are the largest institutional holders of LXEO?
The largest institutional holders of LXEO reported in the latest SEC Form 13F filings include Suvretta Capital Management, Llc, Janus Henderson Group Plc, Affinity Asset Advisors, Llc, Blackrock, Inc., and Ra Capital Management, L.P.. InsiderSet ranks institutional holders by their latest reported LXEO position.
What is LXEO institutional ownership?
This page tracks LXEO positions reported by institutional investment managers through SEC Form 13F. LEXEO THERAPEUTICS INC (LXEO) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own LXEO?
InsiderSet currently tracks 143 institutional managers reporting LXEO holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of LXEO shareholders.
How much LXEO stock do institutions own?
Institutional investment managers disclosed approximately $417.22M in LXEO holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was LXEO institutional ownership last updated?
The latest LXEO institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional LXEO holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its LXEO position after the reporting date.
Are institutions buying or selling LXEO?
Institutional buying and selling can be analyzed by comparing LXEO positions across consecutive 13F reporting periods. InsiderSet's LXEO Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View LXEO ownership changes.
How has LXEO institutional ownership changed over time?
InsiderSet tracks LXEO institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.