LEXEO THERAPEUTICS INC (LXEO) Institutional Shareholders
LEXEO THERAPEUTICS INC (LXEO) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $420.74M in LXEO holdings during the latest filing period.
Suvretta Capital Management, Llc is currently the largest disclosed institutional shareholder of LXEO tracked by InsiderSet, reporting ownership valued at approximately $29.72M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $26.81M, representing an estimated loss of -9.77% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 56% of the total disclosed LXEO value among the investors covered in this analysis. Major shareholders include Suvretta Capital Management, Llc, Janus Henderson Group Plc, Affinity Asset Advisors, Llc, and several other long-term asset managers with concentrated positions in LEXEO THERAPEUTICS INC (LXEO).
This page ranks the largest institutional LXEO shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
141
Total Reported Value
$420.74M
Largest Holder
Suvretta Capital Management, Llc
Largest Position
$29.72M
Insider Transactions (90d)
11
Latest Filing Quarter
Q2 2026
New Institutional Positions
105
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Suvretta Capital Management, Llc | 0.62% | 6,384,200 | $29,718,451 | $26,813,640 | -$2,904,811 | -9.77% | |
| Janus Henderson Group Plc | 0.01% | 4,976,429 | $28,510,358 | $20,901,002 | -$7,609,356 | -26.69% | |
| Affinity Asset Advisors, Llc | 1.32% | 5,807,611 | $27,034,429 | $24,391,966 | -$2,642,463 | -9.77% | |
| Blackrock, Inc. | 0.00% | 5,739,455 | $26,717,165 | $24,105,711 | -$2,611,454 | -9.77% | |
| Ra Capital Management, L.P. | 0.20% | 5,000,000 | $23,275,000 | $21,000,000 | -$2,275,000 | -9.77% | |
| Frazier Life Sciences Management, L.P. | 0.49% | 4,824,725 | $22,459,095 | $20,263,845 | -$2,195,250 | -9.77% | |
| State Street Corp | 0.00% | 4,354,757 | $20,271,394 | $18,289,979 | -$1,981,415 | -9.77% | |
| Vestal Point Capital, Lp | 0.47% | 4,320,000 | $20,109,600 | $18,144,000 | -$1,965,600 | -9.77% | |
| Paradigm Biocapital Advisors Lp | 0.36% | 4,175,382 | $19,436,403 | $17,536,604 | -$1,899,799 | -9.77% | |
| Orbimed Advisors Llc | 0.35% | 3,947,850 | $18,377,242 | $16,580,970 | -$1,796,272 | -9.77% | |
| Citadel Advisors Llc | 0.01% | 3,898,570 | $18,147,843 | $16,373,994 | -$1,773,849 | -9.77% | |
| Vanguard Capital Management Llc | 0.00% | 3,125,893 | $14,551,032 | $13,128,751 | -$1,422,281 | -9.77% | |
| Millennium Management Llc | 0.01% | 2,833,622 | $13,190,510 | $11,901,212 | -$1,289,298 | -9.77% | |
| Woodline Partners Lp | 0.04% | 2,500,532 | $11,639,976 | $10,502,234 | -$1,137,742 | -9.77% | |
| Balyasny Asset Management L.P. | 0.02% | 2,412,742 | $11,231,314 | $10,133,516 | -$1,097,798 | -9.77% | |
| Goldman Sachs Group Inc | 0.00% | 2,149,612 | $10,006,444 | $9,028,370 | -$978,074 | -9.77% | |
| 683 Capital Management, Llc | 0.80% | 1,875,000 | $8,728,124 | $7,875,000 | -$853,124 | -9.77% | |
| Geode Capital Management, Llc | 0.00% | 1,747,959 | $8,138,547 | $7,341,428 | -$797,119 | -9.79% | |
| Adar1 Capital Management, Llc | 0.34% | 1,565,950 | $7,289,497 | $6,576,990 | -$712,507 | -9.77% | |
| Avoro Capital Advisors Llc | 0.06% | 1,489,189 | $6,932,175 | $6,254,594 | -$677,581 | -9.77% | |
| Qube Research & Technologies Ltd | 0.01% | 1,376,222 | $6,406,313 | $5,780,132 | -$626,181 | -9.77% | |
| Nantahala Capital Management, Llc | 0.37% | 1,300,000 | $6,051,500 | $5,460,000 | -$591,500 | -9.77% | |
| Dimensional Fund Advisors Lp | 0.00% | 1,287,185 | $5,992,745 | $5,406,177 | -$586,568 | -9.79% | |
| Spruce Street Capital Lp | 0.85% | 928,593 | $4,322,600 | $3,900,091 | -$422,509 | -9.77% | |
| Blackstone Inc. | 0.01% | 904,959 | $4,217,109 | $3,800,828 | -$416,281 | -9.87% | |
| Northern Trust Corp | 0.00% | 867,391 | $4,037,705 | $3,643,042 | -$394,663 | -9.77% | |
| Aberdeen Group Plc | 0.00% | 675,092 | $3,142,553 | $2,835,386 | -$307,167 | -9.77% | |
| Vanguard Portfolio Management Llc | 0.00% | 613,826 | $2,857,360 | $2,578,069 | -$279,291 | -9.77% | |
| Ikarian Capital, Llc | 0.39% | 513,011 | $2,388,066 | $2,154,646 | -$233,420 | -9.77% | |
| Bank Of America Corp | 0.00% | 490,331 | $2,282,490 | $2,059,390 | -$223,100 | -9.77% | |
| Vanguard Fiduciary Trust Co | 0.00% | 430,696 | $2,004,890 | $1,808,923 | -$195,967 | -9.77% | |
| Morgan Stanley | 0.00% | 395,102 | $1,839,200 | $1,659,428 | -$179,772 | -9.77% | |
| Bnp Paribas Financial Markets | 0.00% | 388,398 | $1,807,993 | $1,631,272 | -$176,721 | -9.77% | |
| Dafna Capital Management Llc | 0.33% | 377,059 | $1,755,210 | $1,583,648 | -$171,562 | -9.77% | |
| Ubs Group Ag | 0.00% | 354,044 | $1,648,074 | $1,486,985 | -$161,089 | -9.77% | |
| Trexquant Investment Lp | 0.01% | 314,891 | $1,465,818 | $1,322,542 | -$143,276 | -9.77% | |
| Squarepoint Ops Llc | 0.00% | 294,774 | $1,372,173 | $1,238,051 | -$134,122 | -9.77% | |
| Hennion & Walsh Asset Management, Inc. | 0.04% | 265,697 | $1,236,820 | $1,115,927 | -$120,893 | -9.77% | |
| Aqr Capital Management Llc | 0.00% | 256,661 | $1,194,757 | $1,077,976 | -$116,781 | -9.77% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 250,365 | $1,165,449 | $1,051,533 | -$113,916 | -9.77% |
| Wellington Management Group Llp | 0.00% | 202,383 | $942,093 | $850,009 | -$92,084 | -9.77% | |
| Nuveen, Llc | 0.00% | 200,417 | $932,941 | $841,751 | -$91,190 | -9.77% | |
| Bank Of New York Mellon Corp | 0.00% | 183,883 | $855,975 | $772,309 | -$83,666 | -9.77% | |
| Charles Schwab Investment Management Inc | 0.00% | 172,609 | $803,495 | $724,958 | -$78,537 | -9.77% | |
| Susquehanna Portfolio Strategies, Llc | 0.01% | 161,062 | $749,744 | $676,460 | -$73,284 | -9.77% | |
| Privium Fund Management B.V. | 0.13% | 155,000 | $722,300 | $651,000 | -$71,300 | -9.87% | |
| Xtx Topco Ltd | 0.01% | 145,556 | $677,563 | $611,335 | -$66,228 | -9.77% | |
| Fmr Llc | 0.00% | 141,146 | $657,035 | $592,813 | -$64,222 | -9.77% | |
| Boothbay Fund Management, Llc | 0.01% | 136,377 | $634,835 | $572,783 | -$62,052 | -9.77% | |
| Burkehill Global Management, Lp | 0.02% | 125,000 | $581,875 | $525,000 | -$56,875 | -9.77% |
Frequently asked questions about LXEO
Who owns the most LXEO stock?
The largest holders of LXEO are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for LEXEO THERAPEUTICS INC (LXEO).
Is LXEO widely held by superinvestors?
Many widely followed stocks like LXEO appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly LXEO is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.