LEXEO THERAPEUTICS INC (LXEO) Institutional Ownership Changes & 13F Activity
LEXEO THERAPEUTICS INC (LXEO). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Janus Henderson Group Plc, Ra Capital Management, L.P., Paradigm Biocapital Advisors Lp, Vestal Point Capital, Lp, and Citadel Advisors Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Sunbelt Securities, Inc. | Buy | +16 | — | 16 | $159.00 | Q4 2025 | Feb 20, 2026 |
| Ikarian Capital, Llc | Buy | +513,011 | — | 513,011 | $5.09M | Q4 2025 | Feb 18, 2026 |
| Raymond James Financial Inc | Buy | +12,538 | — | 12,538 | $124.50K | Q4 2025 | Feb 18, 2026 |
| Janus Henderson Group Plc | Buy | +5,509,635 | — | 5,509,635 | $54.67M | Q4 2025 | Feb 17, 2026 |
| Ra Capital Management, L.P. | Buy | +5,000,000 | — | 5,000,000 | $49.65M | Q4 2025 | Feb 17, 2026 |
| Paradigm Biocapital Advisors Lp | Buy | +4,763,198 | — | 4,763,198 | $47.30M | Q4 2025 | Feb 17, 2026 |
| Vestal Point Capital, Lp | Buy | +4,475,000 | — | 4,475,000 | $44.44M | Q4 2025 | Feb 17, 2026 |
| Citadel Advisors Llc | Buy | +3,774,317 | — | 3,774,317 | $37.48M | Q4 2025 | Feb 17, 2026 |
| Avoro Capital Advisors Llc | Buy | +3,300,000 | — | 3,300,000 | $32.77M | Q4 2025 | Feb 17, 2026 |
| Woodline Partners Lp | Buy | +3,197,760 | — | 3,197,760 | $31.75M | Q4 2025 | Feb 17, 2026 |
| Orbimed Advisors Llc | Buy | +2,125,000 | — | 2,125,000 | $21.10M | Q4 2025 | Feb 17, 2026 |
| Point72 Asset Management, L.P. | Buy | +1,894,722 | — | 1,894,722 | $18.81M | Q4 2025 | Feb 17, 2026 |
| Octagon Capital Advisors Lp | Buy | +1,725,000 | — | 1,725,000 | $17.13M | Q4 2025 | Feb 17, 2026 |
| Balyasny Asset Management L.P. | Buy | +1,635,026 | — | 1,635,026 | $16.24M | Q4 2025 | Feb 17, 2026 |
| Adar1 Capital Management, Llc | Buy | +1,393,161 | — | 1,393,161 | $13.83M | Q4 2025 | Feb 17, 2026 |
| Suvretta Capital Management, Llc | Buy | +1,250,000 | — | 1,250,000 | $12.41M | Q4 2025 | Feb 17, 2026 |
| 683 Capital Management, Llc | Buy | +1,120,000 | — | 1,120,000 | $11.12M | Q4 2025 | Feb 17, 2026 |
| Millennium Management Llc | Buy | +908,024 | — | 908,024 | $9.02M | Q4 2025 | Feb 17, 2026 |
| D. E. Shaw & Co., Inc. | Buy | +480,205 | — | 480,205 | $4.77M | Q4 2025 | Feb 17, 2026 |
| Northern Trust Corp | Buy | +457,052 | — | 457,052 | $4.54M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Investments, Lp | Buy | +400,567 | — | 400,567 | $3.98M | Q4 2025 | Feb 17, 2026 |
| Dafna Capital Management Llc | Buy | +340,859 | — | 340,859 | $3.38M | Q4 2025 | Feb 17, 2026 |
| Aqr Capital Management Llc | Buy | +337,386 | — | 337,386 | $3.35M | Q4 2025 | Feb 17, 2026 |
| Ameriprise Financial Inc | Buy | +243,294 | — | 243,294 | $2.42M | Q4 2025 | Feb 17, 2026 |
| Bank Of America Corp | Buy | +160,288 | — | 160,288 | $1.59M | Q4 2025 | Feb 17, 2026 |
| Perceptive Advisors Llc | Buy | +139,835 | — | 139,835 | $1.39M | Q4 2025 | Feb 17, 2026 |
| Boothbay Fund Management, Llc | Buy | +136,377 | — | 136,377 | $1.35M | Q4 2025 | Feb 17, 2026 |
| Qube Research & Technologies Ltd | Buy | +133,257 | — | 133,257 | $1.32M | Q4 2025 | Feb 17, 2026 |
| Burkehill Global Management, Lp | Buy | +125,000 | — | 125,000 | $1.24M | Q4 2025 | Feb 17, 2026 |
| Wellington Management Group Llp | Buy | +83,230 | — | 83,230 | $826.47K | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about LXEO activity
Which institutional owners are buying LXEO?
Institutional owners buying LXEO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in LXEO activity?
"Buy" means an investor increased their reported position in LXEO compared to the prior reporting period. This reflects growing exposure to LEXEO THERAPEUTICS INC (LXEO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in LXEO increasing?
Institutional interest in LXEO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related LXEO Institutional Insights
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- LXEO Insider Trading & SEC Form 4 Activity
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