LEXEO THERAPEUTICS INC (LXEO) Institutional Ownership Changes & 13F Activity

LEXEO THERAPEUTICS INC (LXEO). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Janus Henderson Group Plc, Ra Capital Management, L.P., Paradigm Biocapital Advisors Lp, Vestal Point Capital, Lp, and Citadel Advisors Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Sunbelt Securities, Inc.Buy+16—16$159.00Q4 2025Feb 20, 2026
Ikarian Capital, LlcBuy+513,011—513,011$5.09MQ4 2025Feb 18, 2026
Raymond James Financial IncBuy+12,538—12,538$124.50KQ4 2025Feb 18, 2026
Janus Henderson Group PlcBuy+5,509,635—5,509,635$54.67MQ4 2025Feb 17, 2026
Ra Capital Management, L.P.Buy+5,000,000—5,000,000$49.65MQ4 2025Feb 17, 2026
Paradigm Biocapital Advisors LpBuy+4,763,198—4,763,198$47.30MQ4 2025Feb 17, 2026
Vestal Point Capital, LpBuy+4,475,000—4,475,000$44.44MQ4 2025Feb 17, 2026
Citadel Advisors LlcBuy+3,774,317—3,774,317$37.48MQ4 2025Feb 17, 2026
Avoro Capital Advisors LlcBuy+3,300,000—3,300,000$32.77MQ4 2025Feb 17, 2026
Woodline Partners LpBuy+3,197,760—3,197,760$31.75MQ4 2025Feb 17, 2026
Orbimed Advisors LlcBuy+2,125,000—2,125,000$21.10MQ4 2025Feb 17, 2026
Point72 Asset Management, L.P.Buy+1,894,722—1,894,722$18.81MQ4 2025Feb 17, 2026
Octagon Capital Advisors LpBuy+1,725,000—1,725,000$17.13MQ4 2025Feb 17, 2026
Balyasny Asset Management L.P.Buy+1,635,026—1,635,026$16.24MQ4 2025Feb 17, 2026
Adar1 Capital Management, LlcBuy+1,393,161—1,393,161$13.83MQ4 2025Feb 17, 2026
Suvretta Capital Management, LlcBuy+1,250,000—1,250,000$12.41MQ4 2025Feb 17, 2026
683 Capital Management, LlcBuy+1,120,000—1,120,000$11.12MQ4 2025Feb 17, 2026
Millennium Management LlcBuy+908,024—908,024$9.02MQ4 2025Feb 17, 2026
D. E. Shaw & Co., Inc.Buy+480,205—480,205$4.77MQ4 2025Feb 17, 2026
Northern Trust CorpBuy+457,052—457,052$4.54MQ4 2025Feb 17, 2026
Two Sigma Investments, LpBuy+400,567—400,567$3.98MQ4 2025Feb 17, 2026
Dafna Capital Management LlcBuy+340,859—340,859$3.38MQ4 2025Feb 17, 2026
Aqr Capital Management LlcBuy+337,386—337,386$3.35MQ4 2025Feb 17, 2026
Ameriprise Financial IncBuy+243,294—243,294$2.42MQ4 2025Feb 17, 2026
Bank Of America CorpBuy+160,288—160,288$1.59MQ4 2025Feb 17, 2026
Perceptive Advisors LlcBuy+139,835—139,835$1.39MQ4 2025Feb 17, 2026
Boothbay Fund Management, LlcBuy+136,377—136,377$1.35MQ4 2025Feb 17, 2026
Qube Research & Technologies LtdBuy+133,257—133,257$1.32MQ4 2025Feb 17, 2026
Burkehill Global Management, LpBuy+125,000—125,000$1.24MQ4 2025Feb 17, 2026
Wellington Management Group LlpBuy+83,230—83,230$826.47KQ4 2025Feb 17, 2026
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Frequently asked questions about LXEO activity

  • Which institutional owners are buying LXEO?

    Institutional owners buying LXEO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in LXEO activity?

    "Buy" means an investor increased their reported position in LXEO compared to the prior reporting period. This reflects growing exposure to LEXEO THERAPEUTICS INC (LXEO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in LXEO increasing?

    Institutional interest in LXEO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.