Maze Therapeutics, Inc. (MAZE) Institutional Ownership Changes & 13F Activity
Maze Therapeutics, Inc. (MAZE). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Arch Venture Management, Llc, Janus Henderson Group Plc, A16Z Capital Management, L.L.C., Venrock Adviser, Llc, and General Catalyst Group Management, Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Cornerstone Financial Management Llc | Buy | +28 | — | 28 | $1.16K | Q4 2025 | Aug 28, 2026 |
| Ensign Peak Advisors, Inc | Buy | +115,129 | +162.9% | 185,794 | $7.70M | Q4 2025 | Aug 18, 2026 |
| Sunbelt Securities, Inc. | Buy | +12 | — | 12 | $497.00 | Q4 2025 | Feb 20, 2026 |
| Ikarian Capital, Llc | Buy | +644,680 | — | 644,680 | $26.71M | Q4 2025 | Feb 18, 2026 |
| Raymond James Financial Inc | Buy | +67,718 | — | 67,718 | $2.81M | Q4 2025 | Feb 18, 2026 |
| Arch Venture Management, Llc | Buy | +4,120,053 | — | 4,120,053 | $170.69M | Q4 2025 | Feb 17, 2026 |
| Janus Henderson Group Plc | Buy | +3,142,587 | — | 3,142,587 | $130.20M | Q4 2025 | Feb 17, 2026 |
| A16Z Capital Management, L.L.C. | Buy | +1,702,225 | — | 1,702,225 | $70.52M | Q4 2025 | Feb 17, 2026 |
| Venrock Adviser, Llc | Buy | +1,548,569 | — | 1,548,569 | $64.16M | Q4 2025 | Feb 17, 2026 |
| General Catalyst Group Management, Llc | Buy | +1,035,910 | — | 1,035,910 | $42.92M | Q4 2025 | Feb 17, 2026 |
| Woodline Partners Lp | Buy | +1,035,229 | — | 1,035,229 | $42.89M | Q4 2025 | Feb 17, 2026 |
| Logos Global Management Lp | Buy | +950,000 | — | 950,000 | $39.36M | Q4 2025 | Feb 17, 2026 |
| Bellevue Group Ag | Buy | +887,708 | — | 887,708 | $36.78M | Q4 2025 | Feb 17, 2026 |
| Arrowmark Colorado Holdings Llc | Buy | +767,383 | — | 767,383 | $31.79M | Q4 2025 | Feb 17, 2026 |
| Casdin Capital, Llc | Buy | +758,857 | — | 758,857 | $31.44M | Q4 2025 | Feb 17, 2026 |
| Fmr Llc | Buy | +728,605 | — | 728,605 | $30.19M | Q4 2025 | Feb 17, 2026 |
| Caligan Partners Lp | Buy | +550,191 | — | 550,191 | $22.79M | Q4 2025 | Feb 17, 2026 |
| Foresite Capital Management Iv, Llc | Buy | +522,657 | — | 522,657 | $21.65M | Q4 2025 | Feb 17, 2026 |
| Squadron Capital Management Llc | Buy | +490,000 | — | 490,000 | $20.30M | Q4 2025 | Feb 17, 2026 |
| Hhlr Advisors, Ltd. | Buy | +457,535 | — | 457,535 | $18.96M | Q4 2025 | Feb 17, 2026 |
| Citadel Advisors Llc | Buy | +448,217 | — | 448,217 | $18.57M | Q4 2025 | Feb 17, 2026 |
| Boothbay Fund Management, Llc | Buy | +409,372 | — | 409,372 | $16.96M | Q4 2025 | Feb 17, 2026 |
| Driehaus Capital Management Llc | Buy | +378,015 | — | 378,015 | $15.66M | Q4 2025 | Feb 17, 2026 |
| Parkman Healthcare Partners Llc | Buy | +209,266 | — | 209,266 | $8.67M | Q4 2025 | Feb 17, 2026 |
| Balyasny Asset Management L.P. | Buy | +199,212 | — | 199,212 | $8.25M | Q4 2025 | Feb 17, 2026 |
| Adar1 Capital Management, Llc | Buy | +179,532 | — | 179,532 | $7.44M | Q4 2025 | Feb 17, 2026 |
| Northern Trust Corp | Buy | +176,259 | — | 176,259 | $7.30M | Q4 2025 | Feb 17, 2026 |
| Tcg Crossover Management, Llc | Buy | +173,816 | — | 173,816 | $7.20M | Q4 2025 | Feb 17, 2026 |
| Highvista Strategies Llc | Buy | +170,353 | — | 170,353 | $7.06M | Q4 2025 | Feb 17, 2026 |
| Millennium Management Llc | Buy | +154,470 | — | 154,470 | $6.40M | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about MAZE activity
Which institutional owners are buying MAZE?
Institutional owners buying MAZE include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in MAZE activity?
"Buy" means an investor increased their reported position in MAZE compared to the prior reporting period. This reflects growing exposure to Maze Therapeutics, Inc. (MAZE) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in MAZE increasing?
Institutional interest in MAZE can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related MAZE Institutional Insights
- MAZE Overview
- MAZE 13F Institutional Holders
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- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
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- MAZE Insider Trading & SEC Form 4 Activity
- MAZE Articles
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