SPRB Institutional Ownership & Shareholders
SPRUCE BIOSCIENCES INC (SPRB) is currently held by 68 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $106.82M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Aigh Capital Management Llc is currently the largest disclosed institutional shareholder of SPRB tracked by InsiderSet, reporting ownership valued at approximately $12.14M in its September 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $11.60M, representing an estimated loss of -4.51% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 65% of the total disclosed SPRB value among the investors covered in this analysis. Major shareholders include Aigh Capital Management Llc, Orbimed Advisors Llc, Blackrock, Inc., and several other long-term asset managers with concentrated positions in SPRUCE BIOSCIENCES INC (SPRB).
This page ranks the largest institutional SPRB shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
68
Total Reported Value
$106.82M
Largest Holder
Aigh Capital Management Llc
Largest Position
$12.14M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
79
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Aigh Capital Management Llc | 1.38% | 250,000 | $12,145,000 | $11,597,500 | -$547,500 | -4.51% | |
| Orbimed Advisors Llc | 0.20% | 200,000 | $10,800,000 | $9,278,000 | -$1,522,000 | -14.09% | |
| Blackrock, Inc. | 0.00% | 187,836 | $10,143,144 | $8,713,712 | -$1,429,432 | -14.09% | |
| Millennium Management Llc | 0.01% | 160,981 | $8,692,974 | $7,467,909 | -$1,225,065 | -14.09% | |
| Ikarian Capital, Llc | 1.07% | 121,356 | $6,553,224 | $5,629,705 | -$923,519 | -14.09% | |
| Vanguard Capital Management Llc | 0.00% | 119,331 | $6,443,874 | $5,535,765 | -$908,109 | -14.09% | |
| Alyeska Investment Group, L.P. | 0.01% | 81,671 | $4,410,234 | $3,788,718 | -$621,516 | -14.09% | |
| Geode Capital Management, Llc | 0.00% | 70,548 | $3,809,975 | $3,272,722 | -$537,253 | -14.10% | |
| Adar1 Capital Management, Llc | 0.17% | 67,717 | $3,656,718 | $3,141,392 | -$515,326 | -14.09% | |
| Cable Car Capital, Lp | 0.07% | 60,000 | $3,240,000 | $2,783,400 | -$456,600 | -14.09% | |
| Citadel Advisors Llc | 0.00% | 51,905 | $2,802,870 | $2,407,873 | -$394,997 | -14.09% | |
| State Street Corp | 0.00% | 50,450 | $2,724,300 | $2,340,376 | -$383,925 | -14.09% | |
| Boothbay Fund Management, Llc | 0.04% | 42,080 | $2,272,320 | $1,952,091 | -$320,229 | -14.09% | |
| Stempoint Capital Lp | 0.39% | 41,388 | $2,234,952 | $1,919,989 | -$314,963 | -14.09% | |
| Eversept Partners, Lp | 0.12% | 40,000 | $2,160,000 | $1,855,600 | -$304,400 | -14.09% | |
| Carlyle Group Inc. | 0.02% | 38,620 | $2,085,493 | $1,791,582 | -$293,911 | -14.09% | |
| Goldman Sachs Group Inc | 0.00% | 32,348 | $1,746,792 | $1,500,624 | -$246,168 | -14.09% | |
| Affinity Asset Advisors, Llc | 0.08% | 30,000 | $1,620,000 | $1,391,700 | -$228,300 | -14.09% | |
| Diadema Partners Lp | 0.57% | 30,000 | $1,620,000 | $1,391,700 | -$228,300 | -14.09% | |
| Stonepine Capital Management, Llc | 1.18% | 28,795 | $1,554,930 | $1,335,800 | -$219,130 | -14.09% | |
| Point72 Asset Management, L.P. | 0.00% | 28,278 | $1,527,012 | $1,311,816 | -$215,196 | -14.09% | |
| Quinn Opportunity Partners Llc | 0.07% | 26,810 | $1,447,740 | $1,243,716 | -$204,024 | -14.09% | |
| Ubs Group Ag | 0.00% | 23,381 | $1,262,574 | $1,084,645 | -$177,929 | -14.09% | |
| Exoduspoint Capital Management, Lp | 0.01% | 22,000 | $1,188,000 | $1,020,580 | -$167,420 | -14.09% | |
| Northern Trust Corp | 0.00% | 21,083 | $1,138,482 | $978,040 | -$160,442 | -14.09% | |
| Knott David M Jr | 0.57% | 20,000 | $1,080,000 | $927,800 | -$152,200 | -14.09% | |
| Rosalind Advisors, Inc. | 0.41% | 20,000 | $1,080,000 | $927,800 | -$152,200 | -14.09% | |
| Ameriprise Financial Inc | 0.00% | 18,834 | $1,017,036 | $873,709 | -$143,327 | -14.09% | |
| Vanguard Portfolio Management Llc | 0.00% | 18,496 | $998,784 | $858,029 | -$140,755 | -14.09% | |
| Vanguard Fiduciary Trust Co | 0.00% | 18,361 | $991,494 | $851,767 | -$139,727 | -14.09% | |
| Balyasny Asset Management L.P. | 0.00% | 12,138 | $655,452 | $563,082 | -$92,370 | -14.09% | |
| Dimensional Fund Advisors Lp | 0.00% | 8,813 | $476,650 | $408,835 | -$67,815 | -14.23% | |
| Persistent Asset Partners Ltd | 0.13% | 7,677 | $414,558 | $356,136 | -$58,422 | -14.09% | |
| State Board Of Administration Of Florida Retirement System | 0.00% | 7,182 | $387,828 | $333,173 | -$54,655 | -14.09% | |
| Bank Of New York Mellon Corp | 0.00% | 6,779 | $366,057 | $314,478 | -$51,579 | -14.09% | |
| Charles Schwab Investment Management Inc | 0.00% | 5,896 | $318,384 | $273,515 | -$44,869 | -14.09% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 4,700 | $253,800 | $218,033 | -$35,767 | -14.09% |
| Morgan Stanley | 0.00% | 4,411 | $238,194 | $204,626 | -$33,568 | -14.09% | |
| Pale Fire Capital Se | 0.01% | 3,818 | $206,172 | $177,117 | -$29,055 | -14.09% | |
| Rhumbline Advisers | 0.00% | 3,519 | $190,026 | $163,246 | -$26,780 | -14.09% | |
| Deutsche Bank Ag\ | 0.00% | 2,652 | $143,208 | $123,026 | -$20,182 | -14.09% | |
| Wells Fargo & Company/Mn | 0.00% | 2,329 | $125,766 | $108,042 | -$17,724 | -14.09% | |
| New York State Common Retirement Fund | 0.00% | 1,900 | $102,600 | $88,141 | -$14,459 | -14.09% | |
| Citigroup Inc | 0.00% | 1,265 | $68,310 | $58,683 | -$9,627 | -14.09% | |
| Mirae Asset Global Etfs Holdings Ltd. | 0.00% | 1,252 | $67,608 | $58,080 | -$9,528 | -14.09% | |
| Jpmorgan Chase & Co | 0.00% | 1,127 | $62,977 | $52,282 | -$10,695 | -16.98% | |
| Lion Point Capital, Lp | 0.26% | 1,000 | $54,000 | $46,390 | -$7,610 | -14.09% | |
| Police & Firemen'S Retirement System Of New Jersey | 0.00% | 864 | $46,656 | $40,081 | -$6,575 | -14.09% | |
| Barclays Plc | 0.00% | 674 | $36,396 | $31,267 | -$5,129 | -14.09% | |
| Bnp Paribas Financial Markets | 0.00% | 453 | $24,462 | $21,015 | -$3,447 | -14.09% |
Frequently asked questions about SPRB
Who are the largest institutional holders of SPRB?
The largest institutional holders of SPRB reported in the latest SEC Form 13F filings include Aigh Capital Management Llc, Orbimed Advisors Llc, Blackrock, Inc., Millennium Management Llc, and Ikarian Capital, Llc. InsiderSet ranks institutional holders by their latest reported SPRB position.
What is SPRB institutional ownership?
This page tracks SPRB positions reported by institutional investment managers through SEC Form 13F. SPRUCE BIOSCIENCES INC (SPRB) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own SPRB?
InsiderSet currently tracks 68 institutional managers reporting SPRB holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of SPRB shareholders.
How much SPRB stock do institutions own?
Institutional investment managers disclosed approximately $106.82M in SPRB holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was SPRB institutional ownership last updated?
The latest SPRB institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional SPRB holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its SPRB position after the reporting date.
Are institutions buying or selling SPRB?
Institutional buying and selling can be analyzed by comparing SPRB positions across consecutive 13F reporting periods. InsiderSet's SPRB Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View SPRB ownership changes.
How has SPRB institutional ownership changed over time?
InsiderSet tracks SPRB institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.