Stonepine Capital Management, Llc Portfolio Stock Holdings

Stonepine Capital Management, Llc disclosed 65 stock positions valued at approximately $112.8 million in its latest SEC 13F filing. The largest holdings include VERASTEM INC, TENAX THERAPEUTICS INC, and EVOLUS INC. The filing reflects positions held as of March 31, 2026 and was filed on May 14, 2026.

Report Period
March 31, 2026
No. of Stocks
65
Portfolio Value
$112.8M
Holdings by Sector
Stonepine Capital Management, Llc Portfolio Holdings in Q1 2026

41 holdings in the latest reporting period.

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CompanySymbolSectorPortfolio %SharesChange (Shares)Change %Value
VERASTEM INCVSTMHealthcare15.52%3,302,300+570,221+20.87%$17,502,190
TENAX THERAPEUTICS INCTENXHealthcare13.83%975,200+963,316+8105.99%$15,593,448
EVOLUS INCEOLSHealthcare6.41%1,759,091+127,503+7.81%$7,229,864
ADMA BIOLOGICS INCADMAHealthcare5.91%740,000--$6,667,400
ZEVRA THERAPEUTICS INCZVRAHealthcare3.97%480,000-89,088-15.65%$4,473,600
CORBUS PHARMACEUTICALS HLDGSCRBPHealthcare3.19%383,462-6,454-1.66%$3,600,708
ABEONA THERAPEUTICS INCABEOHealthcare2.97%746,587+37,082+5.23%$3,344,710
AN2 THERAPEUTICS INCANTXHealthcare2.17%713,845+86,177+13.73%$2,441,350
XOMA ROYALTY CORPORATIONXOMAHealthcare1.93%69,500-45,500-39.57%$2,180,215
AYTU BIOPHARMA INCAYTUHealthcare1.92%792,289-21,415-2.63%$2,162,949
CURIS INCCRISHealthcare1.81%3,726,406+3,667,057+6178.80%$2,039,462
TELA BIO INCTELAHealthcare1.44%2,617,252+265,220+11.28%$1,622,696
INHIBIKASE THERAPEUTICS INCIKTHealthcare1.43%957,202-1,390,945-59.24%$1,608,099
HERON THERAPEUTICS INCHRTXHealthcare1.00%1,402,191+164,389+13.28%$1,121,893
PULMONX CORPLUNGHealthcare0.88%768,288+281,888+57.95%$991,092
SURROZEN INCSRZNHealthcare0.85%33,005-80,626-70.95%$961,436
PMV PHARMACEUTICALS INCPMVPHealthcare0.78%708,102-442,657-38.47%$878,046
MAXCYTE INCMXCTHealthcare0.63%1,004,673+535,655+114.21%$705,783
CODEXIS INCCDXSHealthcare0.60%417,994+161,888+63.21%$681,330
BOUNDLESS BIO INCBOLDHealthcare0.58%597,682-112,389-15.83%$657,450
ZENTALIS PHARMACEUTICALS INCZNTLHealthcare0.56%269,100-194,600-41.97%$629,694
PHATHOM PHARMACEUTICALS INCPHATHealthcare0.49%50,010+50,010+100.00%$555,611
CANDEL THERAPEUTICS INCCADLHealthcare0.45%102,500+102,500+100.00%$502,250
PRECISION OPTICS CORP INC MAPOCIHealthcare0.39%100,000+100,000+100.00%$439,000
ESTABLISHMENT LABS HLDGS INCESTAOther0.30%6,000+6,000+100.00%$340,680
OPUS GENETICS INCOCUPOther0.28%68,688+68,688+100.00%$312,530
ARVINAS INCARVNHealthcare0.26%27,500+27,500+100.00%$291,500
PLIANT THERAPEUTICS INCPLRXHealthcare0.25%224,650-5,400-2.35%$283,059
JANUX THERAPEUTICS INCJANXHealthcare0.25%20,000--$278,000
OMNIAB INCOABIHealthcare0.23%164,045-536,955-76.60%$257,551
XERIS BIOPHARMA HOLDINGS INCXERSHealthcare0.21%40,030+40,030+100.00%$232,174
COMPUGEN LTDCGENOther0.20%104,300-201,100-65.85%$222,159
NEUMORA THERAPEUTICS INC.NMRAHealthcare0.17%100,000+100,000+100.00%$195,000
SAB BIOTHERAPEUTICS INCSABSHealthcare0.17%50,000+50,000+100.00%$191,500
SI BONE INCSIBNHealthcare0.17%14,964+14,964+100.00%$188,995
EDESA BIOTECH INCEDSAHealthcare0.14%30,000-657,500-95.64%$156,900
CABALETTA BIO INCCABAHealthcare0.12%50,000-121,100-70.78%$134,500
ELEDON PHARMACEUTICALS INCELDNHealthcare0.10%35,000-858,100-96.08%$107,800
OVID THERAPEUTICS INCOVIDHealthcare0.08%40,000-62,367-60.92%$88,800
MANNKIND CORPMNKDHealthcare0.04%16,300-70,059-81.13%$39,935
BIOATLA INCBCABHealthcare0.01%65,387+65,387+100.00%$10,527
Stonepine Capital Management, Llc Options Holdings in Q1 2026

16 options positions in the latest reporting period.

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QuarterSymbolCompanyOptionContractsNotional Value
Q1 2026XBISPDR Series Trust SPDR S&P BioPUT400,000$51,092,000
Q1 2026ADMAADMA Biologics IncCALL1,150,000$10,361,500
Q1 2026TERNTerns Pharmaceuticals, Inc.CALL100,000$5,272,000
Q1 2026ESTAEstablishment LabsCALL50,000$2,839,000
Q1 2026AREAlexandria Real Estate EquitiesCALL50,000$2,321,000
Q1 2026ACADACADIA Pharmaceuticals Inc.CALL100,000$2,226,000
Q1 2026EOLSEvolus, Inc. Common StockCALL420,000$1,726,200
Q1 2026XERSXeris Biopharma Holdings, Inc.CALL280,000$1,624,000
Q1 2026SIBNSI-BONE, Inc.CALL100,000$1,263,000
Q1 2026MNKDMannKind CorporationCALL500,000$1,225,000
Q1 2026NMRANeumora Therapeutics, Inc.CALL500,000$975,000
Q1 2026CTMXCytomX Therapeutics, Inc.CALL200,000$940,000
Q1 2026DCTHDelcath Systems, Inc.CALL100,000$928,000
Q1 2026ARDXArdelyx, Inc.CALL150,000$898,500
Q1 2026HRTXHeron Therapeutics, Inc.CALL1,000,000$800,100
Q1 2026ABEOAbeona Therapeutics Inc.CALL100,000$448,000

Notional value represents the total exposure of the options position.