AYTU BIOPHARMA INC (AYTU) Top Institutional Shareholders
AYTU BIOPHARMA INC (AYTU) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $14.22M in AYTU holdings during the latest filing period.
Arete Wealth Advisors, Llc is currently the largest disclosed institutional shareholder of AYTU tracked by InsiderSet, reporting ownership valued at approximately $3.99M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $104,300.645, representing an estimated loss of -97.39% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 96% of the total disclosed AYTU value among the investors covered in this analysis. Major shareholders include Arete Wealth Advisors, Llc, Nantahala Capital Management, Llc, Stonepine Capital Management, Llc, and several other long-term asset managers with concentrated positions in AYTU BIOPHARMA INC (AYTU).
This page ranks the largest institutional AYTU shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
33
Total Reported Value
$14.22M
Largest Holder
Arete Wealth Advisors, Llc
Largest Position
$3.99M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
41
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Arete Wealth Advisors, Llc | 0.30% | 49,549 | $3,990,316 | $104,301 | -$3,886,015 | -97.39% | |
| Nantahala Capital Management, Llc | 0.19% | 1,086,812 | $2,966,997 | $2,287,739 | -$679,258 | -22.89% | |
| Stonepine Capital Management, Llc | 1.92% | 792,289 | $2,162,949 | $1,667,768 | -$495,181 | -22.89% | |
| Awm Investment Company, Inc. | 0.19% | 619,574 | $1,691,437 | $1,304,203 | -$387,234 | -22.89% | |
| Diadema Partners Lp | 0.40% | 353,077 | $963,900 | $743,227 | -$220,673 | -22.89% | |
| Vanguard Capital Management Llc | 0.00% | 261,146 | $712,929 | $549,712 | -$163,217 | -22.89% | |
| Two Sigma Investments, Lp | 0.00% | 121,973 | $332,986 | $256,753 | -$76,233 | -22.89% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 93,723 | $255,864 | $197,287 | -$58,577 | -22.89% |
| Persistent Asset Partners Ltd | 0.10% | 92,897 | $253,609 | $195,548 | -$58,061 | -22.89% | |
| Geode Capital Management, Llc | 0.00% | 92,636 | $252,933 | $194,999 | -$57,934 | -22.90% | |
| Vanguard Fiduciary Trust Co | 0.00% | 47,048 | $128,441 | $99,036 | -$29,405 | -22.89% | |
| Dimensional Fund Advisors Lp | 0.00% | 43,585 | $118,987 | $91,746 | -$27,241 | -22.89% | |
| Citadel Advisors Llc | 0.00% | 36,841 | $100,576 | $77,550 | -$23,026 | -22.89% | |
| Bellevue Asset Management, Llc | 0.03% | 25,013 | $68,285 | $52,652 | -$15,633 | -22.89% | |
| Blackrock, Inc. | 0.00% | 22,793 | $62,225 | $47,979 | -$14,246 | -22.89% | |
| Xtx Topco Ltd | 0.00% | 21,582 | $58,919 | $45,430 | -$13,489 | -22.89% | |
| Northern Trust Corp | 0.00% | 19,169 | $52,331 | $40,351 | -$11,980 | -22.89% | |
| Daytona Street Capital Llc | 0.02% | 10,000 | $26,800 | $21,050 | -$5,750 | -21.46% | |
| Mai Capital Management | 0.00% | 3,575 | $9,760 | $7,525 | -$2,235 | -22.90% | |
| Ubs Group Ag | 0.00% | 1,661 | $4,534 | $3,496 | -$1,038 | -22.88% | |
| Tower Research Capital Llc (Trc) | 0.00% | 1,564 | $4,270 | $3,292 | -$978 | -22.90% | |
| Osaic Holdings, Inc. | 0.00% | 462 | $1,259 | $973 | -$286 | -22.76% | |
| Crown Advisors Management, Inc. | 0.26% | 145,000 | $395 | $305,225 | +$304,830 | +77172.15% | |
| Wells Fargo & Company/Mn | 0.00% | 127 | $347 | $267 | -$80 | -22.96% | |
| Morgan Stanley | 0.00% | 125 | $341 | $263 | -$78 | -22.84% | |
| Group One Trading Llc | 0.00% | 37 | $101 | $78 | -$23 | -22.89% | |
| Bnp Paribas Financial Markets | 0.00% | 23 | $63 | $48 | -$15 | -23.15% | |
| Sbi Securities Co., Ltd. | 0.00% | 11 | $30 | $23 | -$7 | -22.82% | |
| Acadian Asset Management Llc | 0.00% | 10,237 | $27 | $21,549 | +$21,522 | +79710.69% | |
| Rockefeller Capital Management L.P. | 0.00% | 10 | $27 | $21 | -$6 | -22.04% | |
| Vision Financial Markets Llc | 0.00% | 2 | $6 | $4 | -$2 | -29.83% | |
| Caitong International Asset Management Co., Ltd | 0.00% | 2 | $5 | $4 | -$1 | -15.80% | |
| Jones Financial Companies Lllp | 0.00% | 1 | $3 | $2 | -$1 | -29.83% |
Frequently asked questions about AYTU
Who owns the most AYTU stock?
The largest holders of AYTU are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for AYTU BIOPHARMA INC (AYTU).
Is AYTU widely held by superinvestors?
Many widely followed stocks like AYTU appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly AYTU is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.