INSM Institutional Ownership & Shareholders
INSMED INC (INSM) is currently held by 685 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $23.50B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Fmr Llc is currently the largest disclosed institutional shareholder of INSM tracked by InsiderSet, reporting ownership valued at approximately $1.72B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $1.82B, representing an estimated gain of +5.59% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 44% of the total disclosed INSM value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Vanguard Portfolio Management Llc, and several other long-term asset managers with concentrated positions in INSMED INC (INSM).
This page ranks the largest institutional INSM shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
685
Total Reported Value
$23.50B
Largest Holder
Fmr Llc
Largest Position
$1.72B
Insider Transactions (90d)
10
Latest Filing Quarter
Q2 2026
New Institutional Positions
61
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.07% | 16,143,583 | $1,721,228,828 | $1,817,444,574 | +$96,215,746 | +5.59% | |
| Blackrock, Inc. | 0.03% | 15,807,984 | $1,685,447,191 | $1,779,662,839 | +$94,215,648 | +5.59% | |
| Vanguard Portfolio Management Llc | 0.05% | 10,407,962 | $1,109,696,908 | $1,171,728,362 | +$62,031,454 | +5.59% | |
| Jpmorgan Chase & Co | 0.06% | 10,428,170 | $1,092,246,620 | $1,174,003,379 | +$81,756,759 | +7.49% | |
| Vanguard Capital Management Llc | 0.02% | 9,790,865 | $1,043,902,026 | $1,102,255,582 | +$58,353,556 | +5.59% | |
| Baker Bros. Advisors Lp | 4.70% | 8,796,111 | $937,841,355 | $990,266,176 | +$52,424,821 | +5.59% | |
| Capital International Investors | 0.18% | 8,238,124 | $878,338,960 | $927,448,000 | +$49,109,040 | +5.59% | |
| Darwin Global Management, Ltd. | 17.91% | 6,431,163 | $673,600,013 | $724,020,331 | +$50,420,318 | +7.49% | |
| Ameriprise Financial Inc | 0.13% | 6,179,571 | $658,878,001 | $695,696,103 | +$36,818,102 | +5.59% | |
| Orbis Allan Gray Ltd | 2.23% | 6,076,487 | $647,875,044 | $684,090,906 | +$36,215,862 | +5.59% | |
| State Street Corp | 0.02% | 6,052,174 | $645,282,792 | $681,353,749 | +$36,070,957 | +5.59% | |
| D. E. Shaw & Co., Inc. | 0.39% | 5,877,959 | $626,707,989 | $661,740,624 | +$35,032,635 | +5.59% | |
| Artisan Partners Limited Partnership | 0.95% | 5,441,718 | $580,195,955 | $612,628,612 | +$32,432,657 | +5.59% | |
| Rtw Investments, Lp | 4.41% | 4,842,880 | $516,347,866 | $545,211,430 | +$28,863,564 | +5.59% | |
| Geode Capital Management, Llc | 0.02% | 4,220,155 | $448,763,113 | $475,105,050 | +$26,341,937 | +5.87% | |
| Price T Rowe Associates Inc | 0.04% | 3,405,290 | $363,073,000 | $383,367,548 | +$20,294,548 | +5.59% | |
| Norges Bank | 0.04% | 3,377,641 | $360,124,083 | $380,254,824 | +$20,130,741 | +5.59% | |
| Ubs Group Ag | 0.04% | 2,584,446 | $275,553,633 | $290,956,931 | +$15,403,298 | +5.59% | |
| Citadel Advisors Llc | 0.16% | 2,556,973 | $272,624,461 | $287,864,020 | +$15,239,559 | +5.59% | |
| Maverick Capital Ltd | 2.07% | 2,150,762 | $229,314,244 | $242,132,786 | +$12,818,542 | +5.59% | |
| Millennium Management Llc | 0.15% | 2,048,005 | $218,358,293 | $230,564,403 | +$12,206,110 | +5.59% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.04% | 1,215,025 | $198,680,888 | $136,787,515 | -$61,893,374 | -31.15% | |
| Qube Research & Technologies Ltd | 0.20% | 1,682,334 | $179,370,451 | $189,397,162 | +$10,026,711 | +5.59% | |
| Westfield Capital Management Co Lp | 0.57% | 1,629,561 | $173,743,795 | $183,455,977 | +$9,712,182 | +5.59% | |
| T. Rowe Price Investment Management, Inc. | 0.11% | 1,622,675 | $173,010,000 | $182,680,752 | +$9,670,752 | +5.59% | |
| Integral Health Asset Management, Llc | 7.00% | 1,600,000 | $170,592,000 | $180,128,000 | +$9,536,000 | +5.59% | |
| Duquesne Family Office Llc | Stanley Druckenmiller | 3.49% | 1,424,690 | $151,900,000 | $160,391,600 | +$8,491,600 | +5.59% |
| Goldman Sachs Group Inc | 0.02% | 1,409,885 | $150,322,007 | $158,724,853 | +$8,402,846 | +5.59% | |
| Vanguard Fiduciary Trust Co | 0.03% | 1,401,552 | $149,433,474 | $157,786,724 | +$8,353,250 | +5.59% | |
| Bellevue Group Ag | 3.13% | 1,393,418 | $148,566,227 | $156,870,998 | +$8,304,771 | +5.59% | |
| Assenagon Asset Management S.A. | 0.14% | 1,266,788 | $144,591,182 | $142,614,993 | -$1,976,189 | -1.37% | |
| Balyasny Asset Management L.P. | 0.26% | 1,326,430 | $141,423,967 | $149,329,489 | +$7,905,522 | +5.59% | |
| Paradigm Biocapital Advisors Lp | 2.65% | 1,325,977 | $141,375,668 | $149,278,491 | +$7,902,823 | +5.59% | |
| Northern Trust Corp | 0.02% | 1,315,325 | $140,239,951 | $148,079,289 | +$7,839,338 | +5.59% | |
| Bank Of New York Mellon Corp | 0.02% | 1,312,756 | $139,965,961 | $147,790,070 | +$7,824,109 | +5.59% | |
| Two Sigma Investments, Lp | 0.10% | 1,242,222 | $132,445,710 | $139,849,353 | +$7,403,643 | +5.59% | |
| Morgan Stanley | 0.01% | 1,233,498 | $131,515,791 | $138,867,205 | +$7,351,414 | +5.59% | |
| Pictet Asset Management Holding Sa | 0.12% | 1,220,353 | $129,804,038 | $137,387,341 | +$7,583,303 | +5.84% | |
| Charles Schwab Investment Management Inc | 0.02% | 1,213,963 | $129,432,735 | $136,667,955 | +$7,235,220 | +5.59% | |
| Hood River Capital Management Llc | 0.82% | 1,056,871 | $112,683,586 | $118,982,537 | +$6,298,951 | +5.59% | |
| Bank Of America Corp | 0.01% | 1,023,114 | $109,084,466 | $115,182,174 | +$6,097,708 | +5.59% | |
| Sei Investments Co | 0.10% | 1,015,870 | $108,312,723 | $114,366,645 | +$6,053,922 | +5.59% | |
| Nwi Management Lp | 6.91% | 1,014,000 | $108,113,000 | $114,156,120 | +$6,043,120 | +5.59% | |
| Castle Hook Partners Lp | 1.13% | 993,310 | $105,906,712 | $111,826,840 | +$5,920,128 | +5.59% | |
| Jennison Associates Llc | 0.06% | 905,094 | $96,501,143 | $101,895,483 | +$5,394,340 | +5.59% | |
| Polar Capital Holdings Plc | 0.27% | 890,872 | $94,984,773 | $100,294,370 | +$5,309,597 | +5.59% | |
| Fil Ltd | 0.07% | 856,214 | $91,289,537 | $96,392,572 | +$5,103,035 | +5.59% | |
| Adage Capital Partners Gp, L.L.C. | 0.13% | 850,000 | $90,627,000 | $95,693,000 | +$5,066,000 | +5.59% | |
| Fiera Capital Corp | 0.33% | 843,042 | $89,885,138 | $94,909,668 | +$5,024,530 | +5.59% | |
| Legal & General Group Plc | 0.02% | 826,431 | $88,114,072 | $93,039,602 | +$4,925,530 | +5.59% |
Frequently asked questions about INSM
Who are the largest institutional holders of INSM?
The largest institutional holders of INSM reported in the latest SEC Form 13F filings include Fmr Llc, Blackrock, Inc., Vanguard Portfolio Management Llc, Jpmorgan Chase & Co, and Vanguard Capital Management Llc. InsiderSet ranks institutional holders by their latest reported INSM position.
What is INSM institutional ownership?
This page tracks INSM positions reported by institutional investment managers through SEC Form 13F. INSMED INC (INSM) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own INSM?
InsiderSet currently tracks 685 institutional managers reporting INSM holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of INSM shareholders.
How much INSM stock do institutions own?
Institutional investment managers disclosed approximately $23.50B in INSM holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was INSM institutional ownership last updated?
The latest INSM institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional INSM holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its INSM position after the reporting date.
Are institutions buying or selling INSM?
Institutional buying and selling can be analyzed by comparing INSM positions across consecutive 13F reporting periods. InsiderSet's INSM Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View INSM ownership changes.
How has INSM institutional ownership changed over time?
InsiderSet tracks INSM institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.